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Currently, a large number of stored tissue samples are unavailable for spectroscopic study without the time consuming and destructive process of paraffin removal. Instead, a structurally sensitive technique, sum frequency generation, and a…

Medical Physics · Physics 2023-10-03 Bryan Semon , Michael Jaffe , Haifeng Wang , Lauren Priddy , Gombojav Ariunbold

Body composition analysis provides valuable insights into aging, disease progression, and overall health conditions. Due to concerns of radiation exposure, two-dimensional (2D) single-slice computed tomography (CT) imaging has been used…

Computer Vision and Pattern Recognition · Computer Science 2025-01-23 Lianrui Zuo , Xin Yu , Dingjie Su , Kaiwen Xu , Aravind R. Krishnan , Yihao Liu , Shunxing Bao , Fabien Maldonado , Luigi Ferrucci , Bennett A. Landman

Imaging mass spectrometry (IMS) is a powerful tool for untargeted, highly multiplexed molecular mapping of tissue in biomedical research. IMS offers a means of mapping the spatial distributions of molecular species in biological tissue with…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Yijie Zhang , Luzhe Huang , Nir Pillar , Yuzhu Li , Lukasz G. Migas , Raf Van de Plas , Jeffrey M. Spraggins , Aydogan Ozcan

Many spectral CT applications require accurate material decomposition. Existing material decomposition algorithms are often susceptible to significant noise magnification or, in the case of one-step model-based approaches, hampered by slow…

Medical Physics · Physics 2025-07-22 Xiao Jiang , Grace J. Gang , J. Webster Stayman

Representation learning offers a conduit to elucidate distinctive features within the latent space and interpret the deep models. However, the randomness of lesion distribution and the complexity of low-quality factors in medical images…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Qingshan Hou , Shuai Cheng , Peng Cao , Jinzhu Yang , Xiaoli Liu , Osmar R. Zaiane , Yih Chung Tham

Spectral imaging is a method in medical x-ray imaging to extract information about the object constituents by the material-specific energy dependence of x-ray attenuation. Contrast-enhanced spectral imaging has been thoroughly investigated,…

Medical Physics · Physics 2021-01-26 Erik Fredenberg , Magnus Aslund , Bjorn Cederstrom , Mats Lundqvist , Mats Danielsson

In this paper, we propose generating synthetic multiple sclerosis (MS) lesions on MRI images with the final aim to improve the performance of supervised machine learning algorithms, therefore avoiding the problem of the lack of available…

Computer Vision and Pattern Recognition · Computer Science 2019-01-18 Mostafa Salem , Sergi Valverde , Mariano Cabezas , Deborah Pareto , Arnau Oliver , Joaquim Salvi , Àlex Rovira , Xavier Lladó

Lesion synthesis methods have made significant progress in generating large-scale synthetic datasets. However, existing approaches predominantly focus on texture synthesis and often fail to accurately model masks for anatomically complex…

Image and Video Processing · Electrical Eng. & Systems 2025-03-11 Weidong Guo , Hantao Zhang , Shouhong Wan , Bingbing Zou , Wanqin Wang , Chenyang Qiu , Peiquan Jin

kin cancer is considered one of the most common type of cancer in several countries. Due to the difficulty and subjectivity in the clinical diagnosis of skin lesions, Computer-Aided Diagnosis systems are being developed for assist experts…

Computer Vision and Pattern Recognition · Computer Science 2022-01-27 José G. M. Esgario , Renato A. Krohling

Existing studies for automated melanoma diagnosis are based on single-time point images of lesions. However, melanocytic lesions de facto are progressively evolving and, moreover, benign lesions can progress into malignant melanoma.…

Computer Vision and Pattern Recognition · Computer Science 2020-06-22 Zhen Yu , Jennifer Nguyen , Xiaojun Chang , John Kelly , Catriona Mclean , Lei Zhang , Victoria Mar , Zongyuan Ge

Deep learning implemented with convolutional network architectures can exceed specialists' diagnostic accuracy. However, whole-image deep learning trained on a given dataset may not generalize to other datasets. The problem arises because…

Computer Vision and Pattern Recognition · Computer Science 2023-05-17 Norsang Lama , R. Joe Stanley , Anand Nambisan , Akanksha Maurya , Jason Hagerty , William V. Stoecker

Local strain engineering is an exciting approach to tune the optoelectronic properties of materials. Two dimensional (2D) materials such as 2D transition metal dichalcogenides (TMDs) are particularly well suited for this purpose because…

Optics · Physics 2020-02-11 Ahmed Raza Khan , Teng Lu , Wendi Ma , Yuerui Lu , Yun Liu

We have previously introduced Spectral Diffusion Posterior Sampling (Spectral DPS) as a framework for accurate one-step material decomposition by integrating analytic spectral system models with priors learned from large datasets. This work…

Medical Physics · Physics 2025-03-31 Xiao Jiang , Grace J. Gang , J. Webster Stayman

Skin lesions segmentation is an important step in the process of automated diagnosis of the skin melanoma. However, the accuracy of segmenting melanomas skin lesions is quite a challenging task due to less data for training, irregular…

Image and Video Processing · Electrical Eng. & Systems 2020-12-29 Sabari Nathan , Priya Kansal

The plasticity of amorphous solids undergoing shear is characterized by quasi-localized rearrangements of particles. While many models of plasticity exist, the precise relationship between plastic dynamics and the structure of a particle's…

Soft Condensed Matter · Physics 2024-06-12 Jason W. Rocks , Sean A. Ridout , Andrea J. Liu

Theoretical calculations of materials have in recent years shown promise in facilitating the analysis of convoluted experimental data. This is particularly invaluable in complex systems or for materials subject to certain environmental…

Deep learning based Computer Aided Diagnosis (CAD) systems have been developed to treat breast ultrasound. Most of them focus on a single ultrasound imaging modality, either using representative static images or the dynamic video of a…

Computer Vision and Pattern Recognition · Computer Science 2023-08-22 Yunwen Huang , Hongyu Hu , Ying Zhu , Yi Xu

Breast cancer is a health problem that affects mainly the female population. An early detection increases the chances of effective treatment, improving the prognosis of the disease. In this regard, computational tools have been proposed to…

Computer Vision and Pattern Recognition · Computer Science 2022-03-01 Steve Tsham Mpinda Ataky , Alessandro Lameiras Koerich

Universal Lesion Detection (ULD) in computed tomography plays an essential role in computer-aided diagnosis. Promising ULD results have been reported by coarse-to-fine two-stage detection approaches, but such two-stage ULD methods still…

Computer Vision and Pattern Recognition · Computer Science 2021-03-24 Han Li , Long Chen , Hu Han , S. Kevin Zhou

Asymmetry analysis based on the overlapping of thermal images proved able to detect inflammation and, predict foot ulceration. This technique involves three main steps: segmentation, geometric transformation, and overlapping. However, the…

Computer Vision and Pattern Recognition · Computer Science 2016-06-14 Naima Kaabouch , Wen-Chen Hu , Yi Chen