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We present a new randomized method for computing the min-plus product (a.k.a., tropical product) of two $n \times n$ matrices, yielding a faster algorithm for solving the all-pairs shortest path problem (APSP) in dense $n$-node directed…

Data Structures and Algorithms · Computer Science 2014-05-23 Ryan Williams

Using the Dominant Reaction Pathways method, we perform an ab-initio quantum-mechanical simulation of a conformational transition of a peptide chain. The method we propose makes it possible to investigate the out-of-equilibrium dynamics of…

Biomolecules · Quantitative Biology 2010-07-30 S. a Beccara , P. Faccioli , G. Garberoglio , M. Sega , F. Pederiva , H. Orland

We investigate multiple testing and variable selection using the Least Angle Regression (LARS) algorithm in high dimensions under the assumption of Gaussian noise. LARS is known to produce a piecewise affine solution path with change points…

Statistics Theory · Mathematics 2022-05-05 J. -M. Azaïs , Y. De Castro

Methods for inference and simulation of linearly constrained Gaussian Markov Random Fields (GMRF) are computationally prohibitive when the number of constraints is large. In some cases, such as for intrinsic GMRFs, they may even be…

Methodology · Statistics 2021-06-04 David Bolin , Jonas Wallin

Efficient exploration of parameter spaces is crucial to extract physical information about the Epoch of Reionization from various observational probes. To this end, we propose a fast technique based on Gaussian Process Regression (GPR)…

Instrumentation and Methods for Astrophysics · Physics 2023-11-01 Barun Maity , Aseem Paranjape , Tirthankar Roy Choudhury

We propose a flexible procedure for large-scale image search by hash functions with kernels. Our method treats binary codes and pairwise semantic similarity as latent and observed variables, respectively, in a probabilistic model based on…

Computer Vision and Pattern Recognition · Computer Science 2016-04-26 Bahadir Ozdemir , Larry S. Davis

This paper presents an efficient multi-fidelity Bayesian optimization approach for analog circuit synthesis. The proposed method can significantly reduce the overall computational cost by fusing the simple but potentially inaccurate…

Systems and Control · Electrical Eng. & Systems 2019-12-03 Shuhan Zhang , Wenlong Lyu , Fan Yang , Changhao Yan , Dian Zhou , Xuan Zeng , Xiangdong Hu

We present an algorithm for the k shortest simple path problem on weighted directed graphs (kSSP) that is based on Eppstein's algorithm for a similar problem in which paths are allowed to contain cycles. In contrast to most other algorithms…

Data Structures and Algorithms · Computer Science 2016-01-13 Denis Kurz , Petra Mutzel

Gaussian processes (GPs) are widely used in nonparametric regression, classification and spatio-temporal modeling, motivated in part by a rich literature on theoretical properties. However, a well known drawback of GPs that limits their use…

Methodology · Statistics 2011-06-29 Anjishnu Banerjee , David Dunson , Surya Tokdar

We present a time dependent variational method to learn the mechanisms of equilibrium reactive processes and efficiently evaluate their rates within a transition path ensemble. This approach builds off variational path sampling methodology…

Chemical Physics · Physics 2023-07-10 Aditya N. Singh , David T. Limmer

Gaussian process is one of the most popular non-parametric Bayesian methodologies for modeling the regression problem. It is completely determined by its mean and covariance functions. And its linear property makes it relatively…

Machine Learning · Statistics 2020-06-16 Wenqi Fang , Huiyun Li , Hui Huang , Shaobo Dang , Zhejun Huang , Zheng Wang

We consider the problem of designing a sparse Gaussian process classifier (SGPC) that generalizes well. Viewing SGPC design as constructing an additive model like in boosting, we present an efficient and effective SGPC design method to…

Machine Learning · Computer Science 2012-06-27 Sundararajan Sellamanickam , Shirish Shevade

Optical scatterometry is a method to measure the size and shape of periodic micro- or nanostructures on surfaces. For this purpose the geometry parameters of the structures are obtained by reproducing experimental measurement results…

Computational Physics · Physics 2020-06-24 Philipp-Immanuel Schneider , Martin Hammerschmidt , Lin Zschiedrich , Sven Burger

In this work we study the non-parametric reconstruction of spatio-temporal dynamical Gaussian processes (GPs) via GP regression from sparse and noisy data. GPs have been mainly applied to spatial regression where they represent one of the…

Machine Learning · Computer Science 2020-10-06 Marco Todescato , Andrea Carron , Ruggero Carli , Gianluigi Pillonetto , Luca Schenato

Monte Carlo Tree Search is a cornerstone algorithm for online planning, and its root-parallel variant is widely used when wall clock time is limited but best performance is desired. In environments with continuous action spaces, how to best…

Artificial Intelligence · Computer Science 2025-12-11 Junlin Xiao , Victor-Alexandru Darvariu , Bruno Lacerda , Nick Hawes

Quantitative analysis of cardiac motion is crucial for assessing cardiac function. This analysis typically uses imaging modalities such as MRI and Echocardiograms that capture detailed image sequences throughout the heartbeat cycle.…

Computer Vision and Pattern Recognition · Computer Science 2024-10-29 Jiewen Yang , Yiqun Lin , Bin Pu , Xiaomeng Li

Efficient and reliable identification and optimization of transition state structures is a longstanding challenge in computational chemistry. Popular chain-of-states methods require hundreds if not thousands of ab initio calculations to…

Chemical Physics · Physics 2025-11-27 Diptarka Hait , Jan D. Estrada Pabón , Martin Stöhr , Todd J. Martínez

We develop an automated variational method for inference in models with Gaussian process (GP) priors and general likelihoods. The method supports multiple outputs and multiple latent functions and does not require detailed knowledge of the…

Machine Learning · Statistics 2018-11-06 Edwin V. Bonilla , Karl Krauth , Amir Dezfouli

Gaussian Probability Path based Generative Models (GPPGMs) generate data by reversing a stochastic process that progressively corrupts samples with Gaussian noise. Despite state-of-the-art results in 3D molecular generation, their…

Machine Learning · Computer Science 2026-02-23 Jingxiang Qu , Wenhan Gao , Ruichen Xu , Yi Liu

The inference of networks of dependencies by Gaussian Graphical models on high-throughput data is an open issue in modern molecular biology. In this paper we provide a comparative study of three methods to obtain small sample and high…

Molecular Networks · Quantitative Biology 2022-03-02 P. F. Stifanelli , T. M. Creanza , R. Anglani , V. C. Liuzzi , S. Mukherjee , N. Ancona