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Related papers: On the periodicity of cardiovascular fluid dynamic…

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It is well known that in the computational fluid dynamics simulations related to the cardiovascular system the enforcement of outflow boundary conditions is a crucial point. In fact, they highly affect the computed flow and a wrong setup…

Fluid Dynamics · Physics 2025-03-05 Zahra Mirzaiyan , Michele Girfoglio , Gianluigi Rozza

In this study, we present a comprehensive numerical analysis of blood flow within human left ventricle models, with particular emphasis on optimizing simulation conditions to enhance the realism and computational efficiency of heart flow…

Cardiovascular disease affects millions of people worldwide and its social and economic cost clearly motivates scientific research. Computer simulation can lead to a better understanding of cardiac physiology, and for pathology presents…

Biological Physics · Physics 2023-02-27 Toby Simpson

Usually, clinicians assess the correct hemodynamic behavior and fetal well-being during the gestational age thanks to their professional expertise, with the support of some indices defined for Doppler fetal waveforms. Although this approach…

Three-dimensional (3D) cardiovascular fluid dynamics simulations typically require hours to days of computing time on a high-performance computing cluster. One-dimensional (1D) and lumped-parameter zero-dimensional (0D) models show great…

Computational Engineering, Finance, and Science · Computer Science 2022-08-12 Martin R. Pfaller , Jonathan Pham , Aekaansh Verma , Luca Pegolotti , Nathan M. Wilson , David W. Parker , Weiguang Yang , Alison L. Marsden

Cardiac fluid dynamics fundamentally involves interactions between complex blood flows and the structural deformations of the muscular heart walls and the thin, flexible valve leaflets. There has been longstanding scientific, engineering,…

Many applications of computational fluid dynamics require multiple simulations of a flow under different input conditions. In this paper, a numerical algorithm is developed to efficiently determine a set of such simulations in which the…

Numerical Analysis · Mathematics 2017-05-29 Max Gunzburger , Nan Jiang , Zhu Wang

Computational fluid dynamics (CFD) is increasingly used to study blood flows in patient-specific arteries for understanding certain cardiovascular diseases. The techniques work quite well for relatively simple problems, but need…

Computational Physics · Physics 2018-10-11 Fande Kong , Vitaly Kheyfets , Ender Finol , Xiao-Chuan Cai

Intracardiac flow patterns are shaped by the coupled motion of the cardiac chambers and heart valves and provide important information about cardiac function. However, clinical flow imaging remains limited by exam times, noise, resolution,…

Image and Video Processing · Electrical Eng. & Systems 2026-05-12 Fanwei Kong , Aaron Brown , Michael Loecher , Perry S. Choi , Lei Shi , Michael Ma , Daniel B. Ennis , Alison Marsden

In numerical simulations of cardiac mechanics, coupling the heart to a model of the circulatory system is essential for capturing physiological cardiac behavior. A popular and efficient technique is to use an electrical circuit analogy,…

One-dimensional (1D) blood flow simulations are extensively used in cardiovascular research due to their computational efficiency and effectiveness in analyzing pulse wave dynamics. Despite their versatility and simplicity, there is a lack…

Quantitative Methods · Quantitative Biology 2025-08-27 Daehyun Kim , Jeffrey Tithof

The simulation of blood flow and pressure in arteries requires outflow boundary conditions that incorporate models of downstream domains. We previously described a coupled multidomain method to couple analytical models of the downstream…

Medical Physics · Physics 2020-07-17 Irene Vignon-Clementel , C. A. Figueroa , K. E. Jansen , C. A. Taylor

A central problem in biomechanical studies of personalised human left ventricular (LV) modelling is estimating the material properties and biophysical parameters from in-vivo clinical measurements in a time frame suitable for use within a…

Applications · Statistics 2019-05-16 Vinny Davies , Umberto Noè , Alan Lazarus , Hao Gao , Benn Macdonald , Colin Berry , Xiaoyu Luo , Dirk Husmeier

Computational fluid dynamics (CFD) is an important tool for the simulation of the cardiovascular function and dysfunction. Due to the complexity of the anatomy, the transitional regime of blood flow in the heart, and the strong mutual…

Patient-specific modeling of cardiovascular flows with high-fidelity is challenging due to its dependence on accurately estimated velocity boundary profiles, which are essential for precise simulations and directly influence wall shear…

Numerical Analysis · Mathematics 2024-11-28 Kabir Bakhshaei , Sajad Salavatidezfouli , Giovanni Stabile , Gianluigi Rozza

Reduced-order models based on physics are a popular choice in cardiovascular modeling due to their efficiency, but they may experience reduced accuracy when working with anatomies that contain numerous junctions or pathological conditions.…

The circulatory system, comprising the heart and blood vessels, is vital for nutrient transport, waste removal, and homeostasis. Traditional computational models often treat cardiac electromechanics and blood flow dynamics separately,…

Virtual studies of ICD behaviour are crucial for testing device functionality in a controlled environment prior to clinical application. Although previous works have shown the viability of using in silico testing for diagnosis, there is a…

Computational Engineering, Finance, and Science · Computer Science 2025-05-05 Hannah Lydon , Milad Kazemi , Martin Bishop , Nicola Paoletti

Background and Objective: Hemodynamic analysis of blood flow through arteries and veins is critical for diagnosing cardiovascular diseases, such as aneurysms and stenoses, and for investigating cardiovascular parameters, such as turbulence…

The immersed boundary (IB) method is a mathematical framework for fluid-structure interaction problems (FSI) that was originally developed to simulate flows around heart valves. Direct comparison of FSI simulations around heart valves…

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