English
Related papers

Related papers: The Optimal Dynamic Treatment Rule SuperLearner: C…

200 papers

Many decision-making problems require ranking individuals by their treatment effects rather than estimating the exact effect magnitudes. Examples include prioritizing patients for preventive care interventions, or ranking customers by the…

Machine Learning · Computer Science 2026-05-27 Henri Arno , Dennis Frauen , Emil Javurek , Thomas Demeester , Stefan Feuerriegel

Dynamic treatment regimes formalize precision medicine as a sequence of decision rules, one for each stage of clinical intervention, that map current patient information to a recommended intervention. Optimal regimes are typically defined…

Methodology · Statistics 2024-07-09 Kyle Duke , Eric B. Laber , Marie Davidian , Michael Newcomb , Brian Mustanksi

Recent statistical and reinforcement learning methods have significantly advanced patient care strategies. However, these approaches face substantial challenges in high-stakes contexts, including missing data, inherent stochasticity, and…

Machine Learning · Computer Science 2024-04-02 Harsh Parikh , Quinn Lanners , Zade Akras , Sahar F. Zafar , M. Brandon Westover , Cynthia Rudin , Alexander Volfovsky

Estimating the average treatment effect (ATE) from observational data is challenging due to selection bias. Existing works mainly tackle this challenge in two ways. Some researchers propose constructing a score function that satisfies the…

Machine Learning · Computer Science 2022-09-07 Yiyan Huang , Cheuk Hang Leung , Shumin Ma , Qi Wu , Dongdong Wang , Zhixiang Huang

We consider off-dynamics reinforcement learning (RL) where one needs to transfer policies across different domains with dynamics mismatch. Despite the focus on developing dynamics-aware algorithms, this field is hindered due to the lack of…

Machine Learning · Computer Science 2024-10-29 Jiafei Lyu , Kang Xu , Jiacheng Xu , Mengbei Yan , Jingwen Yang , Zongzhang Zhang , Chenjia Bai , Zongqing Lu , Xiu Li

The optimal solution to an optimization problem depends on the problem's objective function, constraints, and size. While deep neural networks (DNNs) have proven effective in solving optimization problems, changes in the problem's size,…

Machine Learning · Computer Science 2025-02-17 Nikos A. Mitsiou , Pavlos S. Bouzinis , Panagiotis G. Sarigiannidis , George K. Karagiannidis

We establish a broad methodological foundation for mixed-integer optimization with learned constraints. We propose an end-to-end pipeline for data-driven decision making in which constraints and objectives are directly learned from data…

Optimization and Control · Mathematics 2023-10-30 Donato Maragno , Holly Wiberg , Dimitris Bertsimas , S. Ilker Birbil , Dick den Hertog , Adejuyigbe Fajemisin

The complexity of human cancer often results in significant heterogeneity in response to treatment. Precision medicine offers potential to improve patient outcomes by leveraging this heterogeneity. Individualized treatment rules (ITRs)…

Traditional test-time training (TTT) methods, while addressing domain shifts, often assume a consistent class set, limiting their applicability in real-world scenarios characterized by infinite variety. Open-World Test-Time Training (OWTTT)…

Machine Learning · Computer Science 2024-09-17 Houcheng Su , Mengzhu Wang , Jiao Li , Bingli Wang , Daixian Liu , Zeheng Wang

Attempts from different disciplines to provide a fundamental understanding of deep learning have advanced rapidly in recent years, yet a unified framework remains relatively limited. In this article, we provide one possible way to align…

Machine Learning · Computer Science 2019-10-01 Guan-Horng Liu , Evangelos A. Theodorou

One of the challenges practitioners face when applying structure learning algorithms to their data involves determining a set of hyperparameters; otherwise, a set of hyperparameter defaults is assumed. The optimal hyperparameter…

Machine Learning · Computer Science 2023-06-27 Kiattikun Chobtham , Anthony C. Constantinou

This study presents a systematic comparison of methods for individual treatment assignment, a general problem that arises in many applications and has received significant attention from economists, computer scientists, and social…

Personalized decision-making, aiming to derive optimal treatment regimes based on individual characteristics, has recently attracted increasing attention in many fields, such as medicine, social services, and economics. Current literature…

Methodology · Statistics 2023-02-28 Jianing Chu , Wenbin Lu , Shu Yang

Dynamic treatment regimes are of growing interest across the clinical sciences as these regimes provide one way to operationalize and thus inform sequential personalized clinical decision making. A dynamic treatment regime is a sequence of…

Methodology · Statistics 2013-11-27 Eric B. Laber , Min Qian , Dan J. Lizotte , William E. Pelham , Susan A. Murphy

Inferring unbiased treatment effects has received widespread attention in the machine learning community. In recent years, our community has proposed numerous solutions in standard settings, high-dimensional treatment settings, and even…

Machine Learning · Computer Science 2024-03-19 Krzysztof Kacprzyk , Samuel Holt , Jeroen Berrevoets , Zhaozhi Qian , Mihaela van der Schaar

Online Learning to Rank (OLTR) optimises ranking models using implicit user feedback, such as clicks. Unlike traditional Learning to Rank (LTR) methods that rely on a static set of training data with relevance judgements to learn a ranking…

Machine Learning · Computer Science 2024-12-30 Shuyi Wang

Real world data often exhibits a long-tailed and open-ended (with unseen classes) distribution. A practical recognition system must balance between majority (head) and minority (tail) classes, generalize across the distribution, and…

Computer Vision and Pattern Recognition · Computer Science 2022-08-18 Ziwei Liu , Zhongqi Miao , Xiaohang Zhan , Jiayun Wang , Boqing Gong , Stella X. Yu

Estimating heterogeneous treatment effects (HTEs) is crucial for precision medicine. While multiple studies can improve the generalizability of results, leveraging them for estimation is statistically challenging. Existing approaches often…

Methodology · Statistics 2025-12-22 Cathy Shyr , Boyu Ren , Prasad Patil , Giovanni Parmigiani

One of the main goals of sequential, multiple assignment, randomized trials (SMART) is to find the most efficacious design embedded dynamic treatment regimes. The analysis method known as multiple comparisons with the best (MCB) allows…

Methodology · Statistics 2020-08-07 William J. Artman , Ashkan Ertefaie , Kevin G. Lynch , James R. McKay

In transportation networks, users typically choose routes in a decentralized and self-interested manner to minimize their individual travel costs, which, in practice, often results in inefficient overall outcomes for society. As a result,…

Machine Learning · Computer Science 2022-04-01 Devansh Jalota , Karthik Gopalakrishnan , Navid Azizan , Ramesh Johari , Marco Pavone