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The behavior of living systems is based on the experience they gained through their interactions with the environment [1]. This experience is stored in the complex biochemical networks of cells and organisms to provide a relationship…

Soft Condensed Matter · Physics 2022-02-14 Santiago Muiños-Landin , Keyan Ghazi-Zahedi , Frank Cichos

For navigation, microscopic agents such as biological cells rely on noisy sensory input. In cells performing chemotaxis, such noise arises from the stochastic binding of signaling molecules at low concentrations. Using chemotaxis of sperm…

Biological Physics · Physics 2018-07-04 Justus A. Kromer , Steffen Märcker , Steffen Lange , Christel Baier , Benjamin M. Friedrich

Inspired by bacterial chemotaxis we propose a hydrodynamic molecular scale hunter that can swim and find its target. The system is essentially a stochastic low Reynolds swimmer with ability to move in two dimensional space and sense the…

Soft Condensed Matter · Physics 2015-05-20 Ali Najafi

Cells and microorganisms adopt various strategies to migrate in response to different environmental stimuli. To date, many modeling research has focused on the crawling-based Dictyostelium discoideum (Dd) cells migration induced by…

Tissues and Organs · Quantitative Biology 2021-04-20 Qixuan Wang , Hao Wu

One of simplest examples of navigation found in nature is run-and-tumble chemotaxis. Tumbles reorient cells randomly, and cells can drift toward attractants or away from repellents by biasing the frequency of these events. The post-tumble…

Soft Condensed Matter · Physics 2017-09-14 Julius B. Kirkegaard , Raymond E. Goldstein

Flagellated microorganisms can swim at low Reynolds numbers and adapt to changes in their environment. Specifically, the flagella can switch their shapes or modes through gene expression. In the past decade, efforts have been made to…

Robotics · Computer Science 2024-01-02 Liyuan Tan , Yang Yang , Li Fang , David J. Cappelleri

The locomotion of microorganisms and spermatozoa in complex viscoelastic fluids is of critical importance in many biological processes such as fertilization, infection, and biofilm formation. Depending on their propulsion mechanisms,…

Soft Condensed Matter · Physics 2021-09-14 Gaojin Li , Eric Lauga , Arezoo M. Ardekani

Self-propulsion and navigation due to the sensing of environmental conditions - such as durotaxis and chemotaxis - are remarkable properties of biological cells that cannot be reproduced by single-component self-propelled particles. We…

Soft Condensed Matter · Physics 2024-06-03 Clara Abaurrea-Velasco , Thorsten Auth , Gerhard Gompper

Interactions between microorganisms and their complex flowing environments are essential in many biological systems. We develop a model for microswimmer dynamics in non-Newtonian Poiseuille flows. We predict that swimmers in…

Soft Condensed Matter · Physics 2016-07-14 Arnold J. T. M. Mathijssen , Tyler N. Shendruk , Julia M. Yeomans , Amin Doostmohammadi

Collective cell migration in response to a chemical cue occurs in many biological processes such as morphogenesis and cancer metastasis. Clusters of migratory cells in these systems are capable of responding to gradients of less than 1%…

Biological Physics · Physics 2016-08-24 Julien Varennes , Bumsoo Han , Andrew Mugler

Living cells are capable of interacting with their environments in a variety of ways, including cell signalling, adhesion, and directed motion. These behaviours are often mediated by receptor molecules embedded in the cell membrane, which…

Biological Physics · Physics 2023-10-17 Hannah Sleath , Bortolo Mognetti , Yuval Elani , Lorenzo Di Michele

Locomotion and transport of microorganisms in fluids is an essential aspect of life. Search for food, orientation toward light, spreading of off-spring, and the formation of colonies are only possible due to locomotion. Swimming at the…

Biological Physics · Physics 2015-05-26 Jens Elgeti , Roland G. Winkler , Gerhard Gompper

Magnetotaxis is a well known phenomenon in swimming microorganisms which sense magnetic fields e.g. by incorporating crystalline magnetosomes. In designing artificial active matter with tunable dynamics, external magnetic fields can provide…

Microorganisms are rarely found in Nature swimming freely in an unbounded fluid. Instead, they typically encounter other organisms, hard walls, or deformable boundaries such as free interfaces or membranes. Hydrodynamic interactions between…

Fluid Dynamics · Physics 2013-10-21 Marcelo A. Dias , Thomas R. Powers

The swimming direction of biological or artificial microscale swimmers tends to be randomised over long time-scales by thermal fluctuations. Bacteria use various strategies to bias swimming behaviour and achieve directed motion against a…

We discuss recent progress in the theoretical description of chemotaxis by coupling the diffusion equation of a chemical species to equations describing the motion of sensing microorganisms. In particular, we discuss models for…

Soft Condensed Matter · Physics 2019-02-05 B. Liebchen , H. Löwen

To explore and react to their environment, living micro-swimmers have developed sophisticated strategies for locomotion - in particular, motility with multiple gaits. To understand the physical principles associated with such a behavioural…

Microswimmers display an intriguing ability to navigate through fluids with spatially varying viscosity, a behavior known as viscotaxis, which plays a crucial role in guiding their motion. In this study, we reveal that the orientation…

Fluid Dynamics · Physics 2025-06-25 Takuya Kobayashi , Ryoichi Yamamoto

Hydrodynamic theories effectively describe many-body systems out of equilibrium in terms of a few macroscopic parameters. However, such hydrodynamic parameters are difficult to derive from microscopics. Seldom is this challenge more…

This paper introduces a continuous model for Multi-cellular Developmental Design. The cells are fixed on a 2D grid and exchange "chemicals" with their neighbors during the growth process. The quantity of chemicals that a cell produces, as…

Artificial Intelligence · Computer Science 2007-05-23 Alexandre Devert , Nicolas Bredèche , Marc Schoenauer