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We provide a numerical study of the macroscopic model of [3] derived from an agent-based model for a system of particles interacting through a dynamical network of links. Assuming that the network remodelling process is very fast, the…

We introduce a new method for inference in stochastic epidemic models which uses recursive multinomial approximations to integrate over unobserved variables and thus circumvent likelihood intractability. The method is applicable to a class…

Methodology · Statistics 2021-02-24 Nick Whiteley , Lorenzo Rimella

A critical task in systems biology is the identification of genes that interact to control cellular processes by transcriptional activation of a set of target genes. Many methods have been developed to use statistical correlations in…

Quantitative Methods · Quantitative Biology 2010-11-24 Adam A. Margolin , Kai Wang , Andrea Califano , Ilya Nemenman

Population protocols are a relatively novel computational model in which very resource-limited anonymous agents interact in pairs with the goal of computing predicates. We consider the probabilistic version of this model, which naturally…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-09-20 Vladyslav Melnychuk

We study experiments on interacting populations of humans and AI agents, where both unit types and the interaction network remain unobserved. Although causal effects propagate throughout the system, the goal is to estimate effects on…

Machine Learning · Statistics 2026-03-03 William Overman , Sadegh Shirani , Mohsen Bayati

1. Temporal trends in species distributions are necessary for monitoring changes in biodiversity, which aids policymakers and conservationists in making informed decisions. Dynamic species distribution models are often fitted to ecological…

Applications · Statistics 2024-01-15 Kwaku Peprah Adjei , Rob Cooke , Nick Isaac , Robert B. O'Hara

Assuming a steady-state condition within a cell, metabolic fluxes satisfy an under-determined linear system of stoichiometric equations. Characterizing the space of fluxes that satisfy such equations along with given bounds (and possibly…

Biological Physics · Physics 2017-04-10 Alfredo Braunstein , Anna Paola Muntoni , Andrea Pagnani

Particle dynamics and multi-agent systems provide accurate dynamical models for studying and forecasting the behavior of complex interacting systems. They often take the form of a high-dimensional system of differential equations…

Machine Learning · Computer Science 2023-08-09 Yuxuan Liu , Scott G. McCalla , Hayden Schaeffer

Agent-based modeling (ABM) is a powerful computational approach for studying complex biological and biomedical systems, yet its widespread use remains limited by significant computational demands. As models become increasingly…

Quantitative Methods · Quantitative Biology 2025-04-17 Kerri-Ann Norton , Daniel Bergman , Harsh Vardhan Jain , Trachette Jackson

We describe collective-move Monte Carlo algorithms designed to approximate the overdamped dynamics of self-assembling nanoscale components equipped with strong, short-ranged and anisotropic interactions. Conventional Monte Carlo simulations…

Statistical Mechanics · Physics 2012-04-16 Stephen Whitelam

Mathematical models of infectious diseases, which are in principle analytically tractable, use two general approaches. The first approach, generally known as compartmental modeling, addresses the time evolution of disease propagation at the…

Populations and Evolution · Quantitative Biology 2010-09-16 Pierre-André Noël , Bahman Davoudi , Robert C. Brunham , Louis J. Dubé , Babak Pourbohloul

Probabilistic (or Bayesian) modeling and learning offers interesting possibilities for systematic representation of uncertainty using probability theory. However, probabilistic learning often leads to computationally challenging problems.…

Computation · Statistics 2018-03-14 Andreas Svensson , Thomas B. Schön , Fredrik Lindsten

Developing the ability to comprehensively study infections in small populations enables us to improve epidemic models and better advise individuals about potential risks to their health. We currently have a limited understanding of how…

Applications · Statistics 2014-10-14 Wen Dong , Katherine A. Heller , Alex Sandy Pentland

We introduce an approach to inferring the causal architecture of stochastic dynamical systems that extends rate distortion theory to use causal shielding---a natural principle of learning. We study two distinct cases of causal inference:…

Information Theory · Computer Science 2010-08-23 Susanne Still , James P. Crutchfield , Christopher J. Ellison

Systematic exploration of Agent-Based Models (ABMs) is challenged by the curse of dimensionality and their inherent stochasticity. We present a multi-stage pipeline integrating the systematic design of experiments with machine learning…

Machine Learning · Computer Science 2026-04-07 Paul Saves , Matthieu Mastio , Nicolas Verstaevel , Benoit Gaudou

This study investigates the spatial integration of agent-based models (ABMs) and compartmental models for infectious disease modeling, presenting a novel hybrid approach and examining its implications. ABMs offer detailed insights by…

Populations and Evolution · Quantitative Biology 2025-02-06 Inan Bostanci , Tim Conrad

The premise of this working paper is based around agent-based simulation models and how to go about creating them from given incomplete information. Agent-based simulations are stochastic simulations that revolve around groups of agents…

Multiagent Systems · Computer Science 2019-02-06 Daniel Stroud , Christian Wagner , Peer-Olaf Siebers

Traditional epidemic detection algorithms make decisions using only local information. We propose a novel approach that explicitly models spatial information fusion from several metapopulations. Our method also takes into account…

Computation · Statistics 2015-09-15 Michael Ludkovski , Katherine Shatskikh

While the design of automated knowledge-based sensor scheduling is relevant to many multi-target detection and tracking problems, tracking algorithms are rarely built for this purpose and their outputs provide little flexibility for the…

Applications · Statistics 2016-07-13 Emmanuel Delande , Jeremie Houssineau , Daniel E. Clark

We present a Monte Carlo simulation model of an epidemic spread inspired on physics variables such as temperature, cross section and interaction range, which considers the Plank distribution of photons in the black body radiation to…

Physics and Society · Physics 2021-10-11 José Enrique Amaro , José Nicolás Orce
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