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An important task in data analysis is the discovery of causal relationships between observed variables. For continuous-valued data, linear acyclic causal models are commonly used to model the data-generating process, and the inference of…

This paper focuses on stochastic saddle point problems with decision-dependent distributions. These are problems whose objective is the expected value of a stochastic payoff function and whose data distribution drifts in response to…

Optimization and Control · Mathematics 2022-11-15 Killian Wood , Emiliano Dall'Anese

The signaling apparatus mediating bacterial chemotaxis can adapt to a wide range of persistent external stimuli. In many cases, the bacterial activity returns to its pre-stimulus level exactly and this "perfect adaptability" is robust…

Biological Physics · Physics 2017-10-16 Bernardo A. Mello , Yuhai Tu

Dynamical systems are frequently used to model biological systems. When these models are fit to data it is necessary to ascertain the uncertainty in the model fit. Here we present prediction deviation, a new metric of uncertainty that…

Applications · Statistics 2017-06-08 Benjamin Letham , Portia A. Letham , Cynthia Rudin , Edward P. Browne

Adaptation is used by biological sensory systems to respond to a wide range of environmental signals, by adapting their response properties to the statistics of the stimulus in order to maximize information transmission. We derive rules of…

Neurons and Cognition · Quantitative Biology 2021-04-14 Daniele Conti , Thierry Mora

Linear causal disentanglement is a recent method in causal representation learning to describe a collection of observed variables via latent variables with causal dependencies between them. It can be viewed as a generalization of both…

Machine Learning · Statistics 2024-07-08 Paula Leyes Carreno , Chiara Meroni , Anna Seigal

Irreversibility and acausality of a sub-system are established in exactly soluble harmonic models with reversible and causal dynamics. It is shown that initial conditions, imposed on some dynamical degrees of freedom may break time reversal…

High Energy Physics - Theory · Physics 2015-05-30 Janos Polonyi

We introduce Conformal Decision Theory, a framework for producing safe autonomous decisions despite imperfect machine learning predictions. Examples of such decisions are ubiquitous, from robot planning algorithms that rely on pedestrian…

Identifying variables responsible for changes to a biological system enables applications in drug target discovery and cell engineering. Given a pair of observational and interventional datasets, the goal is to isolate the subset of…

Machine Learning · Computer Science 2025-06-02 Menghua Wu , Umesh Padia , Sean H. Murphy , Regina Barzilay , Tommi Jaakkola

Causal additive models provide a tractable yet expressive framework for causal discovery in the presence of hidden variables. When unobserved backdoor or causal paths exist between two variables, their causal relationship is often…

Machine Learning · Computer Science 2026-05-25 Thong Pham , Takashi Nicholas Maeda , Shohei Shimizu

Conditional-independence-based discovery uses statistical tests to identify a graphical model that represents the independence structure of variables in a dataset. These tests, however, can be unreliable, and algorithms are sensitive to…

Machine Learning · Computer Science 2026-04-21 Philipp M. Faller , Dominik Janzing

Many biological systems are governed by difference equations and exhibit discrete-time dynamics. Examples include the size of a population when generations are non-overlapping, and the incidence of a disease when infections are recorded at…

Populations and Evolution · Quantitative Biology 2025-09-25 Shuyun Jiao , David Waxman

Most work on causality in machine learning assumes that causal relationships are driven by a constant underlying process. However, the flexibility of agents' actions or tipping points in the environmental process can change the qualitative…

We propose a new method to design adaptation algorithms that guarantee a certain prescribed level of performance and are applicable to systems with nonconvex parameterization. The main idea behind the method is, given the desired…

Optimization and Control · Mathematics 2007-05-23 I. Y. Tyukin , D. V. Prokhorov , Cees van Leeuwen

Temporally evolving systems are typically modeled by dynamic equations. A key challenge in accurate modeling is understanding the causal relationships between subsystems, as well as identifying the presence and influence of unobserved…

Methodology · Statistics 2024-10-28 András Telcs , Marcell T. Kurbucz , Antal Jakovác

Learning the dynamic causal structure of time series is a challenging problem. Most existing approaches rely on distributional or structural invariance to uncover underlying causal dynamics, assuming stationary or partially stationary…

Machine Learning · Computer Science 2026-02-27 Dezhi Yang , Qiaoyu Tan , Carlotta Domeniconi , Jun Wang , Lizhen Cui , Guoxian Yu

We describe the results of analytic calculations and computer simulations of adaptive predictors (predictive agents) responding to an evolving chaotic environment and to one another. Our simulations are designed to quantify adaptation and…

adap-org · Physics 2008-02-03 Alfred Hübler , David Pines

We study the problem of causal structure learning from data using optimal transport (OT). Specifically, we first provide a constraint-based method which builds upon lower-triangular monotone parametric transport maps to design conditional…

Methodology · Statistics 2023-05-30 Sina Akbari , Luca Ganassali , Negar Kiyavash

Synchronization of chaos arises between coupled dynamical systems and is very well understood as a temporal phenomena which leads the coupled systems to converge or develop a dependence with time. In this work, we provide a complementary…

Dynamical Systems · Mathematics 2019-10-23 Aditi Kathpalia , Nithin Nagaraj

Continuous adaptation to variable environments is crucial for the survival of living organisms. Here, we analyze how adaptation, forecasting, and resource mobilization towards a target state, termed actionability, interact to determine…

Cell Behavior · Quantitative Biology 2024-04-15 Jose M. G. Vilar , Leonor Saiz
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