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Advances in image registration and machine learning have recently enabled volumetric analysis of postmortem brain tissue from conventional photographs of coronal slabs, which are routinely collected in brain banks and neuropathology…

We developed an automated deep learning system to detect hip fractures from frontal pelvic x-rays, an important and common radiological task. Our system was trained on a decade of clinical x-rays (~53,000 studies) and can be applied to…

Computer Vision and Pattern Recognition · Computer Science 2017-11-20 William Gale , Luke Oakden-Rayner , Gustavo Carneiro , Andrew P. Bradley , Lyle J. Palmer

The precise and accurate segmentation of the vertebral column is essential in the diagnosis and treatment of various orthopedic, neurological, and oncological traumas and pathologies. Segmentation is especially challenging in the presence…

Computer Vision and Pattern Recognition · Computer Science 2016-01-14 Yinong Wang , Jianhua Yao , Holger R. Roth , Joseph E. Burns , Ronald M. Summers

$\bf{Purpose:}$ The goal of this study was (i) to use artificial intelligence to automate the traditionally labor-intensive process of manual segmentation of tumor regions in pathology slides performed by a pathologist and (ii) to validate…

Vertebral body compression fractures are early signs of osteoporosis. Though these fractures are visible on Computed Tomography (CT) images, they are frequently missed by radiologists in clinical settings. Prior research on automatic…

Image and Video Processing · Electrical Eng. & Systems 2022-10-04 Alexey Zakharov , Maxim Pisov , Alim Bukharaev , Alexey Petraikin , Sergey Morozov , Victor Gombolevskiy , Mikhail Belyaev

Accurate segmentation of the left atrium (LA) from cardiac MRI is critical for guiding atrial fibrillation (AF) ablation and constructing biophysical cardiac models. Manual delineation is time-consuming, observer-dependent, and impractical…

Image and Video Processing · Electrical Eng. & Systems 2025-11-08 Fatemeh Hosseinabadi , Seyedhassan Sharifi

Background: The aim of this study was to develop and evaluate a deep learning-based automated segmentation method for hepatic anatomy (i.e., parenchyma, tumors, portal vein, hepatic vein and biliary tree) from the hepatobiliary phase of…

Image and Video Processing · Electrical Eng. & Systems 2025-08-21 Karin A. Olthof , Matteo Fusagli , Bianca Güttner , Tiziano Natali , Bram Westerink , Stefanie Speidel , Theo J. M. Ruers , Koert F. D. Kuhlmann , Andrey Zhylka

The integrity of articular cartilage is a crucial aspect in the early diagnosis of osteoarthritis (OA). Many novel MRI techniques have the potential to assess compositional changes of the cartilage extracellular matrix. Among these…

Computer Vision and Pattern Recognition · Computer Science 2019-12-05 Alejandra Duarte , Chaitra V. Hegde , Aakash Kaku , Sreyas Mohan , José G. Raya

Osteoporosis, characterized by reduced bone mineral density (BMD) and compromised bone microstructure, increases fracture risk in aging populations. While dual-energy X-ray absorptiometry (DXA) is the clinical standard for BMD assessment,…

Image and Video Processing · Electrical Eng. & Systems 2025-06-26 Jiaxing Huang , Heng Guo , Le Lu , Fan Yang , Minfeng Xu , Ge Yang , Wei Luo

This study's objective was to segment spinal metastases in diagnostic MR images using a deep learning-based approach. Segmentation of such lesions can present a pivotal step towards enhanced therapy planning and validation, as well as…

Image and Video Processing · Electrical Eng. & Systems 2020-01-29 Georg Hille , Johannes Steffen , Max Dünnwald , Mathias Becker , Sylvia Saalfeld , Klaus Tönnies

This paper investigates the use of deep learning approaches to estimate the femur caput-collum-diaphyseal (CCD) angle from X-ray images. The CCD angle is an important measurement in the diagnosis of hip problems, and correct prediction can…

Image and Video Processing · Electrical Eng. & Systems 2024-05-28 Muhammad Abdullah , Anne Querfurth , Deepak Bhatia , Mahdi Mantash

Accurate segmentation of the pelvic CTs is crucial for the clinical diagnosis of pelvic bone diseases and for planning patient-specific hip surgeries. With the emergence and advancements of deep learning for digital healthcare, several…

Image and Video Processing · Electrical Eng. & Systems 2021-01-28 Prabhakara Subramanya Jois , Aniketh Manjunath , Thomas Fevens

In this paper we present a new 3D segmentation approach for the vertebrae of the lower thoracic and the lumbar spine in spiral computed tomography datasets. We implemented a multi-step procedure. Its main components are deformable models,…

Computer Vision and Pattern Recognition · Computer Science 2020-12-11 Andre Mastmeyer , Klaus Engelke , Sebastian Meller , Willi Kalender

In this paper a new technique is presented that extracts the geometry of lumbar vertebral bodies from spiral CT scans. Our new multi-step segmentation approach yields highly accurate and precise measurement of the bone mineral density (BMD)…

Computer Vision and Pattern Recognition · Computer Science 2017-05-23 Andre Mastmeyer , Klaus Engelke , Willi Kalender

Accurate segmentation of organ at risk (OAR) play a critical role in the treatment planning of image guided radiation treatment of head and neck cancer. This segmentation task is challenging for both human and automatic algorithms because…

Computer Vision and Pattern Recognition · Computer Science 2019-10-14 Yueyue Wang , Liang Zhao , Zhijian Song , Manning Wang

Bone segmentation from CT images is a task that has been worked on for decades. It is an important ingredient to several diagnostics or treatment planning approaches and relevant to various diseases. As high-quality manual and…

Computer Vision and Pattern Recognition · Computer Science 2018-04-04 André Klein , Jan Warszawski , Jens Hillengaß , Klaus H. Maier-Hein

Planning of radiotherapy involves accurate segmentation of a large number of organs at risk, i.e. organs for which irradiation doses should be minimized to avoid important side effects of the therapy. We propose a deep learning method for…

Image and Video Processing · Electrical Eng. & Systems 2019-07-04 Pawel Mlynarski , Hervé Delingette , Hamza Alghamdi , Pierre-Yves Bondiau , Nicholas Ayache

Osteoporosis is a skeletal disease typically diagnosed using dual-energy X-ray absorptiometry (DXA), which quantifies areal bone mineral density but overlooks bone microarchitecture and surrounding soft tissues. High-resolution peripheral…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Mohseu Rashid Subah , Mohammed Abdul Gani Zilani , Thomas L. Nickolas , Matthew R. Allen , Stuart J. Warden , Rachel K. Surowiec

Accurate lumbar spine segmentation is crucial for diagnosing spinal disorders. Existing methods typically use coarse-grained segmentation strategies that lack the fine detail needed for precise diagnosis. Additionally, their reliance on…

Computer Vision and Pattern Recognition · Computer Science 2026-04-24 Sheng Lian , Jianlong Cai , Dengfeng Pan , Guang-Yong Chen , Hao Xu , Fan Zhang , Guodong Fan , Shuo Li

Quantitative bone single-photon emission computed tomography (QBSPECT) has the potential to provide a better quantitative assessment of bone metastasis than planar bone scintigraphy due to its ability to better quantify activity in…

Computer Vision and Pattern Recognition · Computer Science 2021-05-31 Junyu Chen , Ye Li , Licia P. Luna , Hyun Woo Chung , Steven P. Rowe , Yong Du , Lilja B. Solnes , Eric C. Frey