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Most of the current state-of-the-art methods for tumor segmentation are based on machine learning models trained on manually segmented images. This type of training data is particularly costly, as manual delineation of tumors is not only…

Computer Vision and Pattern Recognition · Computer Science 2019-08-21 Pawel Mlynarski , Hervé Delingette , Antonio Criminisi , Nicholas Ayache

The clinical management of breast cancer depends on an accurate understanding of the tumor and its anatomical context to adjacent tissues and landmark structures. This context may be provided by semantic segmentation methods; however,…

Image and Video Processing · Electrical Eng. & Systems 2023-11-29 Arda Pekis , Vignesh Kannan , Evandros Kaklamanos , Anu Antony , Snehal Patel , Tyler Earnest

$\bf{Purpose:}$ The goal of this study was (i) to use artificial intelligence to automate the traditionally labor-intensive process of manual segmentation of tumor regions in pathology slides performed by a pathologist and (ii) to validate…

Multiple instance learning (MIL) stands as a powerful approach in weakly supervised learning, regularly employed in histological whole slide image (WSI) classification for detecting tumorous lesions. However, existing mainstream MIL methods…

Image and Video Processing · Electrical Eng. & Systems 2024-07-08 Wenhui Zhu , Xiwen Chen , Peijie Qiu , Aristeidis Sotiras , Abolfazl Razi , Yalin Wang

The rich chemical information from tissue metabolomics provides a powerful means to elaborate tissue physiology or tumor characteristics at cellular and tumor microenvironment levels. However, the process of obtaining such information…

Risk stratification (characterization) of tumors from radiology images can be more accurate and faster with computer-aided diagnosis (CAD) tools. Tumor characterization through such tools can also enable non-invasive cancer staging,…

Computer Vision and Pattern Recognition · Computer Science 2019-01-21 Sarfaraz Hussein , Pujan Kandel , Candice W. Bolan , Michael B. Wallace , Ulas Bagci

The visual examination of tissue biopsy sections is fundamental for cancer diagnosis, with pathologists analyzing sections at multiple magnifications to discern tumor cells and their subtypes. However, existing attention-based multiple…

Computer Vision and Pattern Recognition · Computer Science 2024-10-11 Olga Fourkioti , Matt De Vries , Chen Jin , Daniel C. Alexander , Chris Bakal

Oral cancer incidence is rapidly increasing worldwide. The most important determinant factor in cancer survival is early diagnosis. To facilitate large scale screening, we propose a fully automated pipeline for oral cancer detection on…

Image and Video Processing · Electrical Eng. & Systems 2020-09-14 Jiahao Lu , Nataša Sladoje , Christina Runow Stark , Eva Darai Ramqvist , Jan-Michaél Hirsch , Joakim Lindblad

Goal: Squamous cell carcinoma of cervix is one of the most prevalent cancer worldwide in females. Traditionally, the most indispensable diagnosis of cervix squamous carcinoma is histopathological assessment which is achieved under…

Computer Vision and Pattern Recognition · Computer Science 2019-05-28 Ye Tian , Li Yang , Wei Wang , Jing Zhang , Qing Tang , Mili Ji , Yang Yu , Yu Li , Hong Yang , Airong Qian

We present a deep convolutional neural network for breast cancer screening exam classification, trained and evaluated on over 200,000 exams (over 1,000,000 images). Our network achieves an AUC of 0.895 in predicting whether there is a…

Considering the profound transformation affecting pathology practice, we aimed to develop a scalable artificial intelligence (AI) system to diagnose colorectal cancer from whole-slide images (WSI). For this, we propose a deep learning (DL)…

Whole-slide image (WSI) classification in computational pathology is commonly formulated as slide-level Multiple Instance Learning (MIL) with a single global bag representation. However, slide-level MIL is fundamentally underconstrained:…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Syed Fahim Ahmed , Gnanesh Rasineni , Florian Koehler , Abu Zahid Bin Aziz , Mei Wang , Attila Gyulassy , Brian Summa , J. Quincy Brown , Valerio Pascucci , Shireen Y. Elhabian

Objective: We develop a computer-aided diagnosis (CAD) system using deep learning approaches for lesion detection and classification on whole-slide images (WSIs) with breast cancer. The deep features being distinguishing in classification…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Wei-Wen Hsu , Yongfang Wu , Chang Hao , Yu-Ling Hou , Xiang Gao , Yun Shao , Xueli Zhang , Tao He , Yanhong Tai

The automated detection of cancerous tumors has attracted interest mainly during the last decade, due to the necessity of early and efficient diagnosis that will lead to the most effective possible treatment of the impending risk. Several…

Image and Video Processing · Electrical Eng. & Systems 2023-10-13 Vasileios E. Papageorgiou , Pantelis Dogoulis , Dimitrios-Panagiotis Papageorgiou

Signet ring cell carcinoma (SRCC) of the stomach is a rare type of cancer with a slowly rising incidence. It tends to be more difficult to detect by pathologists mainly due to its cellular morphology and diffuse invasion manner, and it has…

Image and Video Processing · Electrical Eng. & Systems 2020-11-19 Fahdi Kanavati , Shin Ichihara , Michael Rambeau , Osamu Iizuka , Koji Arihiro , Masayuki Tsuneki

Determining the primary site of origin for metastatic tumors is one of the open problems in cancer care because the efficacy of treatment often depends on the cancer tissue of origin. Classification methods that can leverage tumor genomic…

Genomics · Quantitative Biology 2019-11-19 Alena Harley

Manual count of mitotic figures, which is determined in the tumor region with the highest mitotic activity, is a key parameter of most tumor grading schemes. It can be, however, strongly dependent on the area selection due to uneven mitotic…

The spatial distributions of different types of cells could reveal a cancer cell growth pattern, its relationships with the tumor microenvironment and the immune response of the body, all of which represent key hallmarks of cancer. However,…

Computer Vision and Pattern Recognition · Computer Science 2018-09-28 Shidan Wang , Tao Wang , Lin Yang , Faliu Yi , Xin Luo , Yikun Yang , Adi Gazdar , Junya Fujimoto , Ignacio I. Wistuba , Bo Yao , ShinYi Lin , Yang Xie , Yousheng Mao , Guanghua Xiao

Brain tumor detection can make the difference between life and death. Recently, deep learning-based brain tumor detection techniques have gained attention due to their higher performance. However, obtaining the expected performance of such…

Image and Video Processing · Electrical Eng. & Systems 2022-02-22 Wessam M. Salama , Ahmed Shokry

Renal Cell Carcinoma is typically asymptomatic at the early stages for many patients. This leads to a late diagnosis of the tumor, where the curability likelihood is lower, and makes the mortality rate of Renal Cell Carcinoma high, with…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Mohamad Mohamad , Francesco Ponzio , Santa Di Cataldo , Damien Ambrosetti , Xavier Descombes
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