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Accurately modeling multi-class cell topology is crucial in digital pathology, as it provides critical insights into tissue structure and pathology. The synthetic generation of cell topology enables realistic simulations of complex tissue…
Histopathology image classification is crucial for the accurate identification and diagnosis of various diseases but requires large and diverse datasets. Obtaining such datasets, however, is often costly and time-consuming due to the need…
Artificial intelligence methods including deep neural networks (DNN) can provide rapid molecular classification of tumors from routine histology with accuracy that matches or exceeds human pathologists. Discerning how neural networks make…
Visual microscopic study of diseased tissue by pathologists has been the cornerstone for cancer diagnosis and prognostication for more than a century. Recently, deep learning methods have made significant advances in the analysis and…
One of the challenges of using machine learning techniques with medical data is the frequent dearth of source image data on which to train. A representative example is automated lung cancer diagnosis, where nodule images need to be…
Deep Learning (DL) models have been successfully applied to many applications including biomedical cell segmentation and classification in histological images. These models require large amounts of annotated data which might not always be…
Data-driven cell tracking and segmentation methods in biomedical imaging require diverse and information-rich training data. In cases where the number of training samples is limited, synthetic computer-generated data sets can be used to…
Training computer-vision related algorithms on medical images for disease diagnosis or image segmentation is difficult due to the lack of training data, labeled samples, and privacy concerns. For this reason, a robust generative method to…
Generating realistic tissue images with annotations is a challenging task that is important in many computational histopathology applications. Synthetically generated images and annotations are valuable for training and evaluating…
Synthetic tumors in medical images offer controllable characteristics that facilitate the training of machine learning models, leading to an improved segmentation performance. However, the existing methods of tumor synthesis yield…
The limited availability of 3D medical image datasets, due to privacy concerns and high collection or annotation costs, poses significant challenges in the field of medical imaging. While a promising alternative is the use of synthesized…
In this paper, we propose a computational framework for 3D volume reconstruction from 2D histological slices using registration algorithms in feature space. To improve the quality of reconstructed 3D volume, first, intensity variations in…
Data scarcity in medical imaging poses significant challenges due to privacy concerns. Diffusion models, a recent generative modeling technique, offer a potential solution by generating synthetic and realistic data. However, questions…
In the realm of dermatological diagnoses, where the analysis of dermatoscopic and microscopic skin lesion images is pivotal for the accurate and early detection of various medical conditions, the costs associated with creating diverse and…
Generative modelling and synthetic data can be a surrogate for real medical imaging datasets, whose scarcity and difficulty to share can be a nuisance when delivering accurate deep learning models for healthcare applications. In recent…
The generation of 3D models from real-world objects has often been accomplished through photogrammetry, i.e., by taking 2D photos from a variety of perspectives and then triangulating matched point-based features to create a textured mesh.…
Due to privacy concerns, obtaining large datasets is challenging in medical image analysis, especially with 3D modalities like Computed Tomography (CT) and Magnetic Resonance Imaging (MRI). Existing generative models, developed to address…
Novel multimodal imaging methods are capable of generating extensive, super high resolution datasets for preclinical research. Yet, a massive lack of annotations prevents the broad use of deep learning to analyze such data. So far, existing…
The usage of medical image data for the training of large-scale machine learning approaches is particularly challenging due to its scarce availability and the costly generation of data annotations, typically requiring the engagement of…
Mainstream deep models for three-dimensional MRI synthesis are either cross-sectional or volumetric depending on the input. Cross-sectional models can decrease the model complexity, but they may lead to discontinuity artifacts. On the other…