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Artificial Neural Networks (ANN) are already heavily involved in methods and applications for frequent tasks in the field of computational chemistry such as representation of potential energy surfaces (PES) and spectroscopic predictions.…

Chemical Physics · Physics 2022-12-23 Silvan Käser , Luis Itza Vazquez-Salazar , Markus Meuwly , Kai Töpfer

Uncertainty estimation for machine learning models is of high importance in many scenarios such as constructing the confidence intervals for model predictions and detection of out-of-distribution or adversarially generated points. In this…

Machine Learning · Computer Science 2022-05-06 Kirill Fedyanin , Evgenii Tsymbalov , Maxim Panov

In machine learning energy potentials for atomic systems, forces are commonly obtained as the negative derivative of the energy function with respect to atomic positions. To quantify aleatoric uncertainty in the predicted energies, a widely…

Machine Learning · Statistics 2023-12-08 Peter Bjørn Jørgensen , Jonas Busk , Ole Winther , Mikkel N. Schmidt

We propose a novel method to capture data points near decision boundary in neural network that are often referred to a specific type of uncertainty. In our approach, we sought to perform uncertainty estimation based on the idea of…

Machine Learning · Computer Science 2021-12-21 Ismail Alarab , Simant Prakoonwit

Simulations at the atomic scale provide a direct and effective way to understand the mechanical properties of materials. In the regime of classical mechanics, simulations for the thermodynamic properties of metals and alloys can be done by…

Computational Physics · Physics 2019-11-05 Ka-Ming Tam , Nicholas Walker , Samuel Kellar , Mark Jarrell

We apply a temporal edge prediction model for weighted dynamic graphs to predict time-dependent changes in molecular structure. Each molecule is represented as a complete graph in which each atom is a vertex and all vertex pairs are…

Machine Learning · Computer Science 2021-06-28 Michael Hunter Ashby , Jenna A. Bilbrey

Neural networks are a commonly used approach to replace physical models with computationally cheap surrogates. Parametric uncertainty quantification can be included in training, assuming that an accurate prior distribution of the model…

Machine Learning · Computer Science 2026-03-12 Heikki Haario , Zhi-Song Liu , Martin Simon , Hendrik Weichel

Deep neural networks are capable of training fast and generalizing well within many domains. Despite their promising performance, deep networks have shown sensitivities to perturbations of their inputs (e.g., adversarial examples) and their…

Machine Learning · Computer Science 2020-07-09 Justin Goodwin , Olivia Brown , Victoria Helus

In the semantic segmentation of street scenes with neural networks, the reliability of predictions is of highest interest. The assessment of neural networks by means of uncertainties is a common ansatz to prevent safety issues. As in…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Kira Maag , Matthias Rottmann , Hanno Gottschalk

Identifying the obstacle space is crucial for path planning. However, generating an accurate obstacle space remains a significant challenge due to various sources of uncertainty, including motion, behavior, and perception limitations. Even…

Robotics · Computer Science 2025-09-30 Jun Xiang , Jun Chen

Predicting the structure of multi-protein complexes is a grand challenge in biochemistry, with major implications for basic science and drug discovery. Computational structure prediction methods generally leverage pre-defined structural…

Biomolecules · Quantitative Biology 2021-01-26 Stephan Eismann , Raphael J. L. Townshend , Nathaniel Thomas , Milind Jagota , Bowen Jing , Ron O. Dror

This work investigates the detection of instabilities that may occur when utilizing deep learning models for image reconstruction tasks. Although neural networks often empirically outperform traditional reconstruction methods, their usage…

Image and Video Processing · Electrical Eng. & Systems 2020-03-31 Jan Macdonald , Maximilian März , Luis Oala , Wojciech Samek

The central approximation made in classical molecular dynamics simulation of materials is the interatomic potential used to calculate the forces on the atoms. Great effort and ingenuity is required to construct viable functional forms and…

Computational Physics · Physics 2019-06-26 Mitchell A. Wood , Mary Alice Cusentino , Brian D. Wirth , Aidan P. Thompson

Deep neural networks (DNNs) have proven to be powerful predictors and are widely used for various tasks. Credible uncertainty estimation of their predictions, however, is crucial for their deployment in many risk-sensitive applications. In…

Machine Learning · Computer Science 2021-12-03 Ido Galil , Ran El-Yaniv

Neural networks have been identified as powerful tools for the study of complex systems. A noteworthy example is the neural network differential equation (NN DE) solver, which can provide functional approximations to the solutions of a wide…

Machine Learning · Computer Science 2021-01-29 Akshunna S. Dogra , William T Redman

Recently, adversarial deception becomes one of the most considerable threats to deep neural networks. However, compared to extensive research in new designs of various adversarial attacks and defenses, the neural networks' intrinsic…

Machine Learning · Computer Science 2019-05-13 Fuxun Yu , Zhuwei Qin , Chenchen Liu , Liang Zhao , Yanzhi Wang , Xiang Chen

Deep neural networks have become widely used, obtaining remarkable results in domains such as computer vision, speech recognition, natural language processing, audio recognition, social network filtering, machine translation, and…

Neural and Evolutionary Computing · Computer Science 2020-02-03 Divya Gopinath , Guy Katz , Corina S. Pasareanu , Clark Barrett

We present a scheme to obtain an inexpensive and reliable estimate of the uncertainty associated with the predictions of a machine-learning model of atomic and molecular properties. The scheme is based on resampling, with multiple models…

Chemical Physics · Physics 2025-10-06 Felix Musil , Michael J. Willatt , Mikhail A. Langovoy , Michele Ceriotti

The deep neural network (DNN) models for object detection using camera images are widely adopted in autonomous vehicles. However, DNN models are shown to be susceptible to adversarial image perturbations. In the existing methods of…

Robotics · Computer Science 2023-03-17 Hyung-Jin Yoon , Hamidreza Jafarnejadsani , Petros Voulgaris

It has been demonstrated that deep neural networks are prone to noisy examples particular adversarial samples during inference process. The gap between robust deep learning systems in real world applications and vulnerable neural networks…

Machine Learning · Computer Science 2018-07-03 Xinhan Di , Pengqian Yu , Meng Tian