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The short pulses of X-ray free electron lasers can produce diffraction patterns with structural information before radiation damage destroys the particle. The particles are injected into the beam in random orientations and they should be…

Data Analysis, Statistics and Probability · Physics 2013-07-31 Miklós Tegze , Gábor Bortel

Distinguishing two objects or point sources located closer than the Rayleigh distance is impossible in conventional microscopy. Understandably, the task becomes increasingly harder with a growing number of particles placed in close…

Interpreting spectroscopy data is a critical bottleneck in automating chemical research and industrial characterization. Particularly within infrared (IR) spectroscopy, identifying compounds in complex, liquid-phase chemical mixtures…

Materials Science · Physics 2026-02-26 Yannah J. U. Melle , Thanh Nguyen , Jeffrey Lopez , Daniel Schwalbe-Koda

Laser Light Scattering (LLS) method, combined with a long-distance microscope was utilized to detect micrometer-sized particles on a smooth substrate. LLS was capable to detect individual particle release, shrink, or fragmentation during…

Plasma Physics · Physics 2023-07-13 D. Shefer , A. Nikipelov , M. van de Kerkhof , V. Banine , J. Beckers

We present an efficient machine learning framework for detection and classification of nanoparticles on surfaces that are detected in the far-field with Coherent Fourier Scatterometry (CFS). We study silicon wafers contaminated with…

Optics · Physics 2020-07-15 D. Kolenov , S. F. Pereira

We present here a real-time analysis of diffraction images acquired at high frame-rate (925 Hz) and its application to macromolecular serial crystallography. The software uses a new signal separation algorithm, able to distinguish the…

The determination of chemical mixture components is vital to a multitude of scientific fields. Oftentimes spectroscopic methods are employed to decipher the composition of these mixtures. However, the sheer density of spectral features…

Astrophysics of Galaxies · Physics 2024-08-29 Zachary T. P. Fried , Brett A. McGuire

We present an analytical description and an experimental realization of interscale mixing microscopy, a diffraction-based imaging technique that is capable of detecting wavelength/10 objects in far-field measurements with both coherent and…

We present a parameter-decoupled superresolution framework for estimating sub-wavelength separations of passive two-point sources without requiring prior knowledge or control of the source. Our theoretical foundation circumvents the need to…

The measurements of size distribution of small particles (e.g. dusts, droplets, bubbles, etc.) are critical for a broad range of applications in environmental science, public health, industrial manufacturing, etc. Laser diffraction (LD), a…

Fluid Dynamics · Physics 2021-03-16 Santosh Kumar. S , Zilong He , Christopher Hogan , Steven Fredericks , Jiarong Hong

Delivering sub-micrometer particles to an intense x-ray focus is a crucial aspect of single-particle diffractive-imaging experiments at x-ray free-electron lasers. Enabling direct visualization of sub-micrometer aerosol particle streams…

In the field of transmission electron microscopy, data interpretation often lags behind acquisition methods, as image processing methods often have to be manually tailored to individual datasets. Machine learning offers a promising approach…

Image and Video Processing · Electrical Eng. & Systems 2021-07-07 C. K. Groschner , Christina Choi , M. C. Scott

We report an interpretation method for deep learning models that allows us to handle high-dimensional spectral data in materials science. The proposed method uses feature extraction and clustering analysis to categorize materials into…

Materials Science · Physics 2025-10-21 Akira Takahashi , Yu Kumagai , Arata Takamatsu , Fumiyasu Oba

We present a simplified model for dynamical diffraction of particles through a periodic thick perfect crystal based on repeated application of a coherent beam splitting unitary at coarse-grained lattice sites. By demanding translational…

Quantum Physics · Physics 2016-12-14 J. Nsofini , K. Ghofrani , D. Sarenac , D. G. Cory , D. A. Pushin

The speckle pattern produced when a laser is scattered by a disordered medium has recently been shown to give a surprisingly accurate or broadband measurement of wavelength. Here it is shown that deep learning is an ideal approach to…

Optics · Physics 2020-06-22 Roopam K. Gupta , Graham D. Bruce , Simon J. Powis , Kishan Dholakia

Laser cutting of semiconductor wafers and transparent dielectrics has become a dominant process in manufacturing industries, encompassing a wide range of applications from flat display panels to microelectronic chips. Limited by the…

The detection and classification of microplastics in water remain a significant challenge due to their diverse properties and the limitations of traditional optical methods. Standard spectroscopic techniques often suffer from the strong…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Leonard Saur , Marc von Pawlowski , Ulrich Gengenbach , Ingo Sieber , Hossein Shirali , Lorenz Wührl , Xiangyu Weng , Rainer Kiko , Christian Pylatiuk

As the advancements in the field of artificial intelligence and nonlinear optics continues new methods can be used to better describe and determine nonlinear optical phenomena. In this research we aimed to analyze the diffraction patterns…

Data Analysis, Statistics and Probability · Physics 2023-02-17 Behnam Pishnamazi , Ehsan Koushki

Current and next-generation particle tracking detectors will incorporate precision timing capabilities with resolutions approaching tens of picoseconds. Using Technology Computer-Aided Design (TCAD) simulations of Low-Gain Avalanche Diode…

Visualizing molecular transformations in real-time requires a structural retrieval method with {\AA}ngstr\"om spatial and femtosecond temporal atomic resolution. Imaging of hydrogen-containing molecules additionally requires an imaging…