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We demonstrate optimization of optical metasurfaces over $10^5$--$10^6$ degrees of freedom in two and three dimensions, 100--1000+ wavelengths ($\lambda$) in diameter, with 100+ parameters per $\lambda^2$. In particular, we show how…

Optics · Physics 2019-06-26 Zin Lin , Victor Liu , Raphaël Pestourie , Steven G. Johnson

Spectroscopic analysis of large biomolecules is critical in a number of applications, including medical diagnostics and label-free biosensing. Recently, it has been shown that Raman spectroscopy of proteins can be used to diagnose some…

We present a method for deriving limits on Raman scattering in structured media and exploit it to constrain the maximum Raman signal resulting from a planewave incident on either a single Raman molecule in the vicinity of a structured…

Surface-Enhanced Raman Scattering (SERS) allows for detection and identification of molecular vibrational fingerprints in minute sample quantities. The SERS process can be also exploited for optical manipulation of molecular vibrations. We…

Plasmon-free surface-enhanced Raman scattering (SERS) substrates have attracted tremendous attention for their abundant sources, excellent chemical stability, superior biocompatibility, good signal uniformity, and unique selectivity to…

Optics · Physics 2021-06-10 Leilei Lan , Yimeng Gao , Xingce Fan , Mingze Li , Qi Hao , Teng Qiu

Giant field enhancement and field singularities are a natural consequence of the commonly employed local-response framework. We show that a more general nonlocal treatment of the plasmonic response leads to new and possibly fundamental…

Single molecule detection, sequencing and conformational mapping of aptamers are important for improving medical and biosensing technologies and for better understanding of biological processes at the molecular level. We obtain vibrational…

Biomolecules · Quantitative Biology 2016-12-05 Siyu He , Hongyuan Li , Zhe He , Dmitri V. Voronine

Currently the extent of nanoplastic in the environment can only be estimated by extrapolation from the plastic waste that can be detected. To be able to quantify the whole extent of the problem, detection methods have to be developed that…

Optics · Physics 2025-11-12 Ambika Shorny , Fritz Steiner , Helmut Hörner , Sarah M. Skoff

Single-molecule detection with chemical specificity is a powerful and much desired tool for biology, chemistry, physics, and sensing technologies. Surface-enhanced spectroscopies enable single molecule studies, yet reliable substrates of…

Mesoscale and Nanoscale Physics · Physics 2008-02-22 D. R. Ward , N. K. Grady , C. S. Levin , N. J. Halas , Y. Wu , P. Nordlander , D. Natelson

Surface enhanced Raman spectroscopy (SERS) is a precise and non-invasive analytical technique that is widely used in chemical analysis, environmental protection, food processing, pharmaceutics, and diagnostic biology. However, it is still a…

Dynamic surface-enhanced Raman spectroscopy (SERS) is nowadays one of the most interesting applications of SERS, in particular for single molecule studies. In fact, it enables the study of real-time processes at the molecular level. This…

We review an on-chip approach for spontaneous Raman spectroscopy and Surface Enhanced Raman Spectroscopy (SERS) based on evanescent excitation of the analyte as well as evanescent collection of the Raman signal using Complementary Metal…

Surface enhanced Raman spectroscopy (SERS) was used to probe the surface chemistry of chlorine-terminated silicon nanocrystal (Si-NC) surfaces in an air-free environment. SERS effect was observed from the thin films of Ag$_x$O using 514 nm…

Materials Science · Physics 2016-06-28 İlker Doğan , Ryan Gresback , Tomohiro Nozaki , Mauritius C. M. van de Sanden

The electromagnetic enhancement for surface enhanced Raman spectroscopy (SERS) of graphene is studied by inserting a layer of Al2O3 between epitaxial graphene and Au nanoparticles. Different excitation lasers are utilized to study the…

Tip enhanced Raman scattering (TERS) amplifies the intensity of vibrational Raman scattering by employing the tip of a probe interacting, in ultra close proximity, with a surface. Although a general understanding of the TERS process is…

With the emergence of new photonic and plasmonic materials with optimized properties as well as advanced nanofabrication techniques, nanophotonic devices are now capable of providing solutions to global challenges in energy conversion,…

This work demonstrates an original and ultrasensitive approach for surface-enhanced Raman spectroscopy (SERS) detection based on evaporation of self-lubricating drops containing silver supraparticles. The developed method detects an…

Chiral nanophotonic platforms provide a means of creating near fields with both enhanced asymmetric properties and intensities. They can be exploited for optical measurements that allow enantiomeric discrimination at detection levels…

The experimental limitations in the signal enhancement and spatial resolution in spectroscopic imaging have been always a challenging task in the application of near-field spectroscopy for nanostructured materials in the sub-diffraction…

Materials Science · Physics 2018-06-11 A. K. Sivadasan , Avinash Patsha , Achyut Maity , Tapas Kumar Chini , Sandip Dhara

Development of fabrication protocols for large-area plasmonic nanostructures with sub-10 nm gaps with a spatially controlled distribution is critical for their real-world applications. In this work, we develop a simple, cleanroom-free…