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The appearance of microcalcifications in mammograms is one of the early signs of breast cancer. So, early detection of microcalcification clusters (MCCs) in mammograms can be helpful for cancer diagnosis and better treatment of breast…

Computer Vision and Pattern Recognition · Computer Science 2012-01-31 Hajar Moradmand , Saeed Setayeshi , Hossein Khazaei Targhi

Breast cancer exhibits intricate morphological and dynamical heterogeneity across cellular, tissue, and tumor scales, posing challenges to conventional modeling approaches that fail to capture its nonlinear, self-similar, or self-affine,…

Quantitative Methods · Quantitative Biology 2025-11-18 Abhijeet Das , Ramray Bhat , Mohit Kumar Jolly

Tissues are fractal due to its self-similar structure, and the fractal dimension change with the abnormalities such as in disease like cancer. The optical imaging of thin slices of tissue using transmission microscopy can produce an…

Biological Physics · Physics 2020-12-29 Liam Elkington , Prakash Adhikari , Prabhakar Pradhan

Microcalcifications are small deposits of calcium that appear in mammograms as bright white specks on the soft tissue background of the breast. Microcalcifications may be a unique indication for Ductal Carcinoma in Situ breast cancer, and…

Computer Vision and Pattern Recognition · Computer Science 2021-02-24 Roee Zamir , Shai Bagon , David Samocha , Yael Yagil , Ronen Basri , Miri Sklair-Levy Meirav Galun

We explored the fractal and multifractal characteristics of breast mammogram micrographs to identify quantitative biomarkers associated with breast cancer progression. In addition to conventional fractal and multifractal analyses, we…

Medical Physics · Physics 2025-05-28 Santanu Maity , Mousa Alrubayan , Prabhakar Pradhan

Cell-based models provide a helpful approach for simulating complex systems that exhibit adaptive, resilient qualities, such as cancer. Their focus on individual cell interactions makes them a particularly appropriate strategy to study the…

Quantitative Methods · Quantitative Biology 2022-11-30 Juan Uriel Legaria-Peña , Félix Sánchez-Morales , Yuriria Cortés-Poza

This paper presents a tumor detection algorithm from mammogram. The proposed system focuses on the solution of two problems. One is how to detect tumors as suspicious regions with a very weak contrast to their background and another is how…

Machine Learning · Computer Science 2009-12-14 Y. Ireaneus Anna Rejani , S. Thamarai Selvi

Cancer is an epidemic worldwide. At present one in four persons has cancer and this statistic will change to one in a two person in the near future. It is now known that war against cancer is the early, curable detection and treatment.…

Tissues and Organs · Quantitative Biology 2017-10-03 Shiva Bhandari , Sri Choudannavar , Ethan Avery , Peeyush Sahay , Prabhakar Pradhan

Microcalcifications in mammogram have been mainly targeted as a reliable earliest sign of breast cancer and their early detection is vital to improve its prognosis. Since their size is very small and may be easily overlooked by the…

Computer Vision and Pattern Recognition · Computer Science 2010-02-11 T. Balakumaran , I. L. A. Vennila , C. Gowri Shankar

Cluster of microcalcifications can be an early sign of breast cancer. In this paper we propose a novel approach based on convolutional neural networks for the detection and segmentation of microcalcification clusters. In this work we used…

Computer Vision and Pattern Recognition · Computer Science 2018-09-12 Gabriele Valvano , Gianmarco Santini , Nicola Martini , Andrea Ripoli , Chiara Iacconi , Dante Chiappino , Daniele Della Latta

In this paper, a novel method for edge detection of microcalcification clusters in mammogram images is presented using the concept of Fractal Dimension and Hurst co-efficient that enables to locate the microcalcifications in the mammograms.…

Computer Vision and Pattern Recognition · Computer Science 2013-05-01 P. Shanmugavadivu , V. Sivakumar

Breast X-ray CT imaging is being considered in screening as an extension to mammography. As a large fraction of the population will be exposed to radiation, low-dose imaging is essential. Iterative image reconstruction based on solving an…

Medical Physics · Physics 2011-11-14 Jakob H. Jørgensen , Emil Y. Sidky , Xiaochuan Pan

Transmission intensity of a thin tissue sample produce intensity distribution that is proportional to the refractive index pattern in the thin slice, in turn reflects mass density pattern, and using the intensity pattern, fractal dimension…

Breast cancer is one of the factors that cause the increase of mortality of women. The most widely used method for diagnosing this geological disease i.e. breast cancer is the ultrasound scan. Several key features such as the smoothness and…

Artificial Intelligence · Computer Science 2021-08-10 Mohamed Mejri , Aymen Mejri , Oumayma Mejri , Chiraz Fekih

The diagnosis and segmentation of tumors using any medical diagnostic tool can be challenging due to the varying nature of this pathology. Magnetic Reso- nance Imaging (MRI) is an established diagnostic tool for various diseases and…

Computer Vision and Pattern Recognition · Computer Science 2017-11-01 Tanvi Gupta , Pranay Manocha , Tapan K. Gandhi , RK Gupta , BK Panigrahi

High-resolution microscopy images of tissue specimens provide detailed information about the morphology of normal and diseased tissue. Image analysis of tissue morphology can help cancer researchers develop a better understanding of cancer…

Mammography is a vital screening technique for early revealing and identification of breast cancer in order to assist to decrease mortality rate. Practical applications of mammograms are not limited to breast cancer revealing,…

Image and Video Processing · Electrical Eng. & Systems 2020-10-08 Aparna Bhale , Manish Joshi

This paper presents an algorithm which aims to assist the radiologist in identifying breast cancer at its earlier stages. It combines several image processing techniques like image negative, thresholding and segmentation techniques for…

Computer Vision and Pattern Recognition · Computer Science 2009-11-04 Y. Ireaneus Anna Rejani , S. Thamarai Selvi

Objective: Breast tissue is mainly a mixture of adipose and fibro-glandular tissue. Cancer risk and risk of undetected breast cancer increases with the amount of glandular tissue in the breast. Therefore, radiologists must report the total…

Medical Physics · Physics 2023-10-12 Bryce J. Smith , Joyoni Dey , Lacey Medlock , David Solis , Krystal Kirby

In the last few years, deep learning classifiers have shown promising results in image-based medical diagnosis. However, interpreting the outputs of these models remains a challenge. In cancer diagnosis, interpretability can be achieved by…

Computer Vision and Pattern Recognition · Computer Science 2021-06-16 Kangning Liu , Yiqiu Shen , Nan Wu , Jakub Chłędowski , Carlos Fernandez-Granda , Krzysztof J. Geras
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