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Infectious diseases pose significant human and economic burdens. Accurately forecasting disease incidence can enable public health agencies to respond effectively to existing or emerging diseases. Despite progress in the field, developing…

Machine Learning · Computer Science 2024-09-04 Michael Morris

Influenza-like illness (ILI) places a heavy social and economic burden on our society. Traditionally, ILI surveillance data is updated weekly and provided at a spatially coarse resolution. Producing timely and reliable high-resolution…

Other Statistics · Statistics 2020-02-13 Lijing Wang , Jiangzhuo Chen , Madhav Marathe

Seasonal influenza epidemics cause consistent, considerable, widespread loss annually in terms of economic burden, morbidity, and mortality. With access to accurate and reliable forecasts of a current or upcoming influenza epidemic's…

Populations and Evolution · Quantitative Biology 2016-02-17 Logan C. Brooks , David C. Farrow , Sangwon Hyun , Ryan J. Tibshirani , Roni Rosenfeld

Background: Over the past few decades, numerous forecasting methods have been proposed in the field of epidemic forecasting. Such methods can be classified into different categories such as deterministic vs. probabilistic, comparative…

We present a machine learning-based methodology capable of providing real-time ("nowcast") and forecast estimates of influenza activity in the US by leveraging data from multiple data sources including: Google searches, Twitter microblogs,…

Applications · Statistics 2016-02-17 Mauricio Santillana , Andre T. Nguyen , Mark Dredze , Michael J. Paul , John S. Brownstein

Seasonal influenza forecasting is critical for public health and individual decision making. We investigate whether the inclusion of data about influenza activity in neighboring states can improve point predictions and distribution…

Applications · Statistics 2024-08-26 Gabrielle Thivierge , Aaron Rumack , F. William Townes

The annual influenza outbreak leads to significant public health and economic burdens making it desirable to have prompt and accurate probabilistic forecasts of the disease spread. The United States Centers for Disease Control and…

Applications · Statistics 2025-08-29 Spencer Wadsworth , Jarad Niemi

Seasonal influenza infects between 10 and 50 million people in the United States every year, overburdening hospitals during weeks of peak incidence. Named by the CDC as an important tool to fight the damaging effects of these epidemics,…

Applications · Statistics 2020-05-19 Thomas McAndrew , Nicholas G. Reich

Over the last ten years, the US Centers for Disease Control and Prevention (CDC) has organized an annual influenza forecasting challenge with the motivation that accurate probabilistic forecasts could improve situational awareness and yield…

Machine Learning · Statistics 2024-07-30 Evan L. Ray , Yijin Wang , Russell D. Wolfinger , Nicholas G. Reich

Accurate and reliable predictions of infectious disease dynamics can be valuable to public health organizations that plan interventions to decrease or prevent disease transmission. A great variety of models have been developed for this…

Machine Learning · Statistics 2018-07-04 Evan L. Ray , Nicholas G. Reich

Accurate forecasts of disease outbreaks are critical for effective public health responses, management of healthcare surge capacity, and communication of public risk. There are a growing number of powerful forecasting methods that fall into…

Accurate epidemic forecasting is critical for informing public health decisions and timely interventions. While Physics-Informed Neural Networks have shown promise in various scientific domains, their potential application to real-time…

Physics and Society · Physics 2026-05-20 Martina Rama , Gabriele Santin , Giulia Cencetti , Michele Tizzoni , Bruno Lepri

Epidemiological forecasting from surveillance data is a hard problem and hybridizing mechanistic compartmental models with neural models is a natural direction. The mechanistic structure helps keep trajectories epidemiologically plausible,…

Machine Learning · Computer Science 2026-02-09 Yiqi Su , Ray Lee , Jiaming Cui , Naren Ramakrishnan

Forecasting the hospitalizations caused by the Influenza virus is vital for public health planning so that hospitals can be better prepared for an influx of patients. Many forecasting methods have been used in real-time during the Influenza…

Machine Learning · Computer Science 2022-06-22 Majd Al Aawar , Ajitesh Srivastava

Timely and robust influenza incidence forecasting is critical for public health decision-making. This paper presents MAESTRO (Multi-modal Adaptive Estimation for Temporal Respiratory Disease Outbreak), a novel, unified framework that…

Machine Learning · Computer Science 2025-09-22 Hong Liu , Kerui Cen , Yanxing Chen , Zige Liu , Dong Chen , Zifeng Yang , Chitin Hon

Health-policy planning requires evidence on the burden that epidemics place on healthcare systems. Multiple, often dependent, datasets provide a noisy and fragmented signal from the unobserved epidemic process including transmission and…

Applications · Statistics 2024-09-11 Alice Corbella , Anne M Presanis , Paul J Birrell , Daniela De Angelis

In this paper, we present a new approach to time series forecasting. Time series data are prevalent in many scientific and engineering disciplines. Time series forecasting is a crucial task in modeling time series data, and is an important…

Machine Learning · Computer Science 2020-01-24 Neo Wu , Bradley Green , Xue Ben , Shawn O'Banion

The characteristics of influenza seasons varies substantially from year to year, posing challenges for public health preparation and response. Influenza forecasting is used to inform seasonal outbreak response, which can in turn potentially…

Applications · Statistics 2022-03-16 Nutcha Wattanachit , Evan L. Ray , Thomas C. McAndrew , Nicholas G. Reich

In this paper, a unified susceptible-exposed-infected-susceptible-aware (SEIS-A) framework is proposed to combine epidemic spreading with individuals' on-line self-consultation behaviors. An epidemic spreading prediction model is…

Computational Engineering, Finance, and Science · Computer Science 2019-12-02 Yun Feng , Bing-Chuan Wang

In the context of Epidemic Intelligence, many Event-Based Surveillance (EBS) systems have been proposed in the literature to promote the early identification and characterization of potential health threats from online sources of any…

Information Retrieval · Computer Science 2023-03-31 Nejat Arinik , Roberto Interdonato , Mathieu Roche , Maguelonne Teisseire
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