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Electronic health records (EHR) consist of longitudinal clinical observations portrayed with sparsity, irregularity, and high-dimensionality, which become major obstacles in drawing reliable downstream clinical outcomes. Although there…

Machine Learning · Computer Science 2020-11-17 Ahmad Wisnu Mulyadi , Eunji Jun , Heung-Il Suk

Health conditions among patients in intensive care units (ICUs) are monitored via electronic health records (EHRs), composed of numerical time series and lengthy clinical note sequences, both taken at irregular time intervals. Dealing with…

Machine Learning · Computer Science 2023-06-07 Xinlu Zhang , Shiyang Li , Zhiyu Chen , Xifeng Yan , Linda Petzold

This study proposes a risk prediction method based on a Multi-Scale Temporal Alignment Network (MSTAN) to address the challenges of temporal irregularity, sampling interval differences, and multi-scale dynamic dependencies in Electronic…

Machine Learning · Computer Science 2025-11-27 Wei-Chen Chang , Lu Dai , Ting Xu

Electronic Health Record (EHR) provides abundant information through various modalities. However, learning multi-modal EHR is currently facing two major challenges, namely, 1) data embedding and 2) cases with missing modality. A lack of…

Machine Learning · Computer Science 2023-05-05 Kwanhyung Lee , Soojeong Lee , Sangchul Hahn , Heejung Hyun , Edward Choi , Byungeun Ahn , Joohyung Lee

While the volume of electronic health records (EHR) data continues to grow, it remains rare for hospital systems to capture dense physiological data streams, even in the data-rich intensive care unit setting. Instead, typical EHR records…

Machine Learning · Computer Science 2018-12-04 Satya Narayan Shukla , Benjamin M. Marlin

The era of big data has made vast amounts of clinical data readily available, particularly in the form of electronic health records (EHRs), which provides unprecedented opportunities for developing data-driven diagnostic tools to enhance…

Machine Learning · Computer Science 2025-03-06 Zekai Wang , Tieming Liu , Bing Yao

Irregular sampling occurs in many time series modeling applications where it presents a significant challenge to standard deep learning models. This work is motivated by the analysis of physiological time series data in electronic health…

Machine Learning · Computer Science 2021-06-08 Satya Narayan Shukla , Benjamin M. Marlin

Multimodal irregular time series (MITS) consist of asynchronous and irregularly sampled observations from heterogeneous numerical and textual channels. In healthcare, for example, patients' electronic health records (EHR) include irregular…

Machine Learning · Computer Science 2026-05-14 Hsing-Huan Chung , Shijun Li , Yoav Wald , Xing Han , Suchi Saria , Joydeep Ghosh

Irregular sampling and high missingness are intrinsic challenges in modeling time series derived from electronic health records (EHRs),where clinical variables are measured at uneven intervals depending on workflow and intervention timing.…

Machine Learning · Computer Science 2025-09-29 Jeong Eul Kwon , Joo Heung Yoon , Hyo Kyung Lee

A patient undergoes multiple examinations in each hospital stay, where each provides different facets of the health status. These assessments include temporal data with varying sampling rates, discrete single-point measurements, therapeutic…

Computer Vision and Pattern Recognition · Computer Science 2025-01-31 Malte Tölle , Mohamad Scharaf , Samantha Fischer , Christoph Reich , Silav Zeid , Christoph Dieterich , Benjamin Meder , Norbert Frey , Philipp Wild , Sandy Engelhardt

Electronic Health Records (EHR) contain valuable clinical information for predicting patient outcomes and guiding healthcare decisions. However, effectively modeling Electronic Health Records (EHRs) requires addressing data heterogeneity…

Machine Learning · Computer Science 2025-07-22 Junhan Yu , Zhunyi Feng , Junwei Lu , Tianxi Cai , Doudou Zhou

With the improvement of medical data capturing, vast amount of continuous patient monitoring data, e.g., electrocardiogram (ECG), real-time vital signs and medications, become available for clinical decision support at intensive care units…

Machine Learning · Computer Science 2018-07-25 Yanbo Xu , Siddharth Biswal , Shriprasad R Deshpande , Kevin O Maher , Jimeng Sun

Irregularly sampled time series (ISTS) data has irregular temporal intervals between observations and different sampling rates between sequences. ISTS commonly appears in healthcare, economics, and geoscience. Especially in the medical…

Machine Learning · Computer Science 2020-10-27 Chenxi Sun , Shenda Hong , Moxian Song , Hongyan Li

The advent of the Internet era has led to an explosive growth in the Electronic Health Records (EHR) in the past decades. The EHR data can be regarded as a collection of clinical events, including laboratory results, medication records,…

Machine Learning · Computer Science 2019-11-14 Zichang Wang , Haoran Li , Luchen Liu , Haoxian Wu , Ming Zhang

A large fraction of the electronic health records (EHRs) consists of clinical measurements collected over time, such as lab tests and vital signs, which provide important information about a patient's health status. These sequences of…

Machine Learning · Statistics 2020-03-02 Karl Øyvind Mikalsen , Cristina Soguero-Ruiz , Robert Jenssen

Electronic health record (EHR) data has emerged as a valuable resource for analyzing patient health status. However, the prevalence of missing data in EHR poses significant challenges to existing methods, leading to spurious correlations…

Machine Learning · Computer Science 2024-05-16 Zhihao Yu , Xu Chu , Yujie Jin , Yasha Wang , Junfeng Zhao

Deep learning models exhibit state-of-the-art performance for many predictive healthcare tasks using electronic health records (EHR) data, but these models typically require training data volume that exceeds the capacity of most healthcare…

Machine Learning · Computer Science 2018-10-24 Edward Choi , Cao Xiao , Walter F. Stewart , Jimeng Sun

Electronic Health Records (EHRs) contain a large volume of heterogeneous patient data, which are useful at the point of care and for retrospective research. These data are typically stored in relational databases. Gaining an integrated view…

Computers and Society · Computer Science 2018-06-04 Dina Levy-Lambert , Jen J. Gong , Tristan Naumann , Tom J. Pollard , John V. Guttag

Electronic health records (EHRs) are designed to synthesize diverse data types, including unstructured clinical notes, structured lab tests, and time-series visit data. Physicians draw on these multimodal and temporal sources of EHR data to…

Irregularly-sampled time series occur in many domains including healthcare. They can be challenging to model because they do not naturally yield a fixed-dimensional representation as required by many standard machine learning models. In…

Machine Learning · Computer Science 2020-08-19 Steven Cheng-Xian Li , Benjamin M. Marlin
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