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Parkinson's disease (PD) is a progressive neurodegenerative disorder that, in addition to directly impairing functional mobility, is frequently associated with vocal impairments such as hypophonia and dysarthria, which typically manifest in…

Changes in speech and language are among the first signs of Parkinson's disease (PD). Thus, clinicians have tried to identify individuals with PD from their voices for years. Doctors can leverage AI-based speech assessments to spot PD…

Sound · Computer Science 2023-12-06 Mahboobeh Parsapoor

Accurate and interpretable gait analysis plays a crucial role in the early detection of Parkinsons disease (PD),yet most existing approaches remain limited by single-modality inputs, low robustness, and a lack of clinical transparency. This…

Computer Vision and Pattern Recognition · Computer Science 2025-12-05 Manar Alnaasan , Md Selim Sarowar , Sungho Kim

In this study, we explored the use of spectrograms to represent handwriting signals for assessing neurodegenerative diseases, including 42 healthy controls (CTL), 35 subjects with Parkinson's Disease (PD), 21 with Alzheimer's Disease (AD),…

Machine Learning · Computer Science 2025-02-12 Sarah Laouedj , Yuzhe Wang , Jesus Villalba , Thomas Thebaud , Laureano Moro-Velazquez , Najim Dehak

In this work, we explore various neural network architectures using Magnetic Resonance (MR) T1 images of the brain to identify Parkinson's Disease (PD), which is one of the most common neurodegenerative and movement disorders. We propose…

Image and Video Processing · Electrical Eng. & Systems 2020-07-27 Tahjid Ashfaque Mostafa , Irene Cheng

Parkinson's disease (PD) is a highly heterogeneous disease, including which motor symptoms are dominating. Imaging biomarkers that support subtype stratification could also improve biological understanding and study design, and enable…

Posturography is routinely used to qualitatively assess one of the cardinal symptoms of Parkinson's disease -- postural instability. While most measures of balance control are derived from displacement of the center of pressure there is…

Neurons and Cognition · Quantitative Biology 2017-10-24 Miroslaw Latka , Slawomir Budrewicz , Klaudia Kozlowska , Magdalena Koszewicz , Bruce J. West

While handwriting has traditionally been studied for character recognition and disease classification, its potential to reflect day-to-day physiological fluctuations in healthy individuals remains unexplored. This study examines whether…

Human-Computer Interaction · Computer Science 2026-04-07 Chisa Tanaka , Andrew Vargo , Anna Scius-Bertrand , Andreas Fischer , Koichi Kise

As one of the most prevalent neurodegenerative disorders, Parkinson's disease (PD) has a significant impact on the fine motor skills of patients. The complex interplay of different articulators during speech production and realization of…

In this paper, by characterizing the Leg Agility (LA) task, which contributes to the evaluation of the degree of severity of the Parkinson's Disease (PD), through kinematic variables (including the angular amplitude and speed of thighs'…

Computers and Society · Computer Science 2015-02-16 Matteo Giuberti , Gianluigi Ferrari , Laura Contin , Veronica Cimolin , Corrado Azzaro , Giovanni Albani , Alessandro Mauro

Parkinson's disease (PD) is a progressive neurodegenerative movement disorder where motor dysfunction gradually increases as the disease progress. In addition to administering dopaminergic PD-specific drugs, attending neurologists strongly…

Computers and Society · Computer Science 2015-11-10 Ioannis Pachoulakis , Nikolaos Papadopoulos , Cleanthe Spanaki

Handwriting disorder (termed dysgraphia) is a far from a singular problem as nearly 8.6% of the population in France is considered dysgraphic. Moreover, research highlights the fundamental importance to detect and remediate these…

Parkinson's disease is a progressive neurodegenerative disorder affecting motor and non-motor functions, with speech impairments among its earliest symptoms. Speech impairments offer a valuable diagnostic opportunity, with machine learning…

Machine Learning · Computer Science 2025-04-25 Lorenzo Simone , Mauro Giuseppe Camporeale , Vito Marco Rubino , Vincenzo Gervasi , Giovanni Dimauro

Purpose. Handwriting is one of the most frequently occurring patterns in everyday life and with it come challenging applications such as handwriting recognition (HWR), writer identification, and signature verification. In contrast to…

Machine Learning · Computer Science 2024-10-08 Felix Ott , David Rügamer , Lucas Heublein , Tim Hamann , Jens Barth , Bernd Bischl , Christopher Mutschler

Accurate diagnosis of Parkinson disease, especially in its early stages, can be a challenging task. The application of machine learning techniques helps improve the diagnostic accuracy of Parkinson disease detection but only few studies…

Machine Learning · Computer Science 2024-12-25 Majid Ali , Hina Shakir , Asia Samreen , Sohaib Ahmed

In the past few years, there are several researches on Parkinson's disease (PD) recognition using single-photon emission computed tomography (SPECT) images with deep learning (DL) approach. However, the DL model's complexity usually results…

Image and Video Processing · Electrical Eng. & Systems 2021-05-05 Theerasarn Pianpanit , Sermkiat Lolak , Phattarapong Sawangjai , Thapanun Sudhawiyangkul , Theerawit Wilaiprasitporn

Background: Parkinson's disease (PD) is a prevalent long-term neurodegenerative disease. Though the diagnostic criteria of PD are relatively well defined, the current medical imaging diagnostic procedures are expertise-demanding, and thus…

Quantitative Methods · Quantitative Biology 2019-02-27 Jiahang Xu , Fangyang Jiao , Yechong Huang , Xinzhe Luo , Qian Xu , Ling Li , Xueling Liu , Chuantao Zuo , Ping Wu , Xiahai Zhuang

Parkinson's Disease (PD) is a progressive nervous system disorder that has affected more than 5.8 million people, especially the elderly. Due to the complexity of its symptoms and its similarity to other neurological disorders, early…

Artificial Intelligence · Computer Science 2022-11-29 Jingwei Li , Ruitian Wu , Tzu-liang Huang , Zian Pan , Ming-chun Huang

In this work, we introduce LightCNN, a minimalist Convolutional Neural Network (CNN) architecture designed for Parkinson's disease (PD) classification using EEG data. LightCNN's strength lies in its simplicity, utilizing just a single…

Machine Learning · Computer Science 2024-08-21 Md Fahim Anjum

Parkinson's disease is an ongoing challenge to theoretical neuroscience and to medical treatment. During the evolution of the disease, neurodegeneration leads to physiological and anatomical changes that affect the neuronal discharge of the…

Neurons and Cognition · Quantitative Biology 2014-03-07 Daniela Sabrina Andres , Florian Gomez , Daniel Cerquetti , Marcelo Merello , Ruedi Stoop