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Functional connectivity analysis is an important tool for characterizing interactions among brain regions, particularly in studies of neurodegenerative disorders such as Alzheimer's disease (AD). Gaussian graphical models (GGMs) provide a…

Methodology · Statistics 2026-04-14 Panpan Zhang , Shiying Xiao , W. Hudson Robb , Dandan Liu , Angela L. Jefferson , Jun Yan

Several causal discovery algorithms have been proposed. However, when the sample size is small relative to the number of variables, the accuracy of estimating causal graphs using existing methods decreases. And some methods are not feasible…

Machine Learning · Statistics 2025-10-06 Ming Cai , Hisayuki Hara

Time series modeling is crucial for many applications, however, it faces challenges such as complex spatio-temporal dependencies and distribution shifts in learning from historical context to predict task-specific outcomes. To address these…

Artificial Intelligence · Computer Science 2024-08-28 Chidaksh Ravuru , Sagar Srinivas Sakhinana , Venkataramana Runkana

While most classical approaches to Granger causality detection assume linear dynamics, many interactions in real-world applications, like neuroscience and genomics, are inherently nonlinear. In these cases, using linear models may lead to…

Machine Learning · Statistics 2021-03-16 Alex Tank , Ian Covert , Nicholas Foti , Ali Shojaie , Emily Fox

Large language models (LLMs) have transformed natural language processing (NLP), enabling diverse applications by integrating large-scale pre-trained knowledge. However, their static knowledge limits dynamic reasoning over external…

Computation and Language · Computer Science 2025-09-26 Harshad Khadilkar , Abhay Gupta

Granger causality is a fundamental technique for causal inference in time series data, commonly used in the social and biological sciences. Typical operationalizations of Granger causality make a strong assumption that every time point of…

Machine Learning · Computer Science 2020-11-23 Chainarong Amornbunchornvej , Elena Zheleva , Tanya Y. Berger-Wolf

Granger causality has been employed to investigate causality relations between components of stationary multiple time series. We generalize this concept by developing statistical inference for local Granger causality for multivariate…

Methodology · Statistics 2025-08-12 Yan Liu , Masanobu Taniguchi , Hernando Ombao

Exploratory analysis of time series data can yield a better understanding of complex dynamical systems. Granger causality is a practical framework for analysing interactions in sequential data, applied in a wide range of domains. In this…

Machine Learning · Computer Science 2021-01-20 Ričards Marcinkevičs , Julia E. Vogt

Characterising cause-effect relationships in complex systems is fundamental to understanding their underlying mechanisms. Granger causality (GC) remains a widely used computational tool for identifying causal relationships in time series…

Machine Learning · Statistics 2026-05-26 S. A. Adedayo

Multi-electrode neurophysiological recordings produce massive quantities of data. Multivariate time series analysis provides the basic framework for analyzing the patterns of neural interactions in these data. It has long been recognized…

Quantitative Methods · Quantitative Biology 2007-05-23 Mingzhou Ding , Yonghong Chen , Steven L. Bressler

Long-sequence causal reasoning seeks to uncover causal relationships within extended time series data but is hindered by complex dependencies and the challenges of validating causal links. To address the limitations of large-scale language…

Computation and Language · Computer Science 2025-01-03 Yuxuan Zhang , Yulong Li , Zichen Yu , Feilong Tang , Zhixiang Lu , Chong Li , Kang Dang , Jionglong Su

Retrieval-Augmented Generation (RAG) has emerged as the predominant paradigm for grounding Large Language Model outputs in factual knowledge, effectively mitigating hallucinations. However, conventional RAG systems operate under a…

Information Retrieval · Computer Science 2026-01-13 Sergii Voloshyn

This paper studies large-scale dynamical networks where the current state of the system is a linear transformation of the previous state, contaminated by a multivariate Gaussian noise. Examples include stock markets, human brains and gene…

Computation · Statistics 2015-06-23 Yiyuan She , Yuejia He , Shijie Li , Dapeng Wu

Large language models (LLMs) often generate outdated or inaccurate information based on static training datasets. Retrieval-augmented generation (RAG) mitigates this by integrating outside data sources. While previous RAG systems used…

Causal discovery from time-series data has been a central task in machine learning. Recently, Granger causality inference is gaining momentum due to its good explainability and high compatibility with emerging deep neural networks. However,…

Machine Learning · Computer Science 2023-02-16 Yuxiao Cheng , Runzhao Yang , Tingxiong Xiao , Zongren Li , Jinli Suo , Kunlun He , Qionghai Dai

Causal interactions in time series networks can be dynamic and nonlinear, making it difficult to identify them using conventional linear causality estimations. We propose a novel approach, called Threshold Autoregressive Modeling for…

Applications · Statistics 2025-09-19 Sipan Aslan , Hernando Ombao

Functional MRI is a neuroimaging technique that analyzes the functional activity of the brain by measuring blood-oxygen-level-dependent signals throughout the brain. The derived functional features can be used for investigating brain…

Neurons and Cognition · Quantitative Biology 2026-02-16 Giorgio Dolci , Silvia Saglia , Lorenza Brusini , Vince D. Calhoun , Ilaria Boscolo Galazzo , Gloria Menegaz

Graph-based retrieval-augmented generation (Graph-based RAG) has demonstrated significant potential in enhancing Large Language Models (LLMs) with structured knowledge. However, existing methods face three critical challenges: Inaccurate…

Machine Learning · Computer Science 2026-03-18 Yubo Wang , Haoyang Li , Fei Teng , Lei Chen

Temporal causal analysis means understanding the underlying causes behind observed variables over time. Deep learning based methods such as transformers are increasingly used to capture temporal dynamics and causal relationships beyond mere…

Machine Learning · Computer Science 2024-11-21 Riya Mahesh , Rahul Vashisht , Chandrashekar Lakshminarayanan

Most of the metrics used for detecting a causal relationship among multiple time series ignore the effects of practical measurement impairments, such as finite sample effects, undersampling and measurement noise. It has been shown that…

Methodology · Statistics 2023-04-03 Rahul Devendra , Ribhu Chopra , Kumar Appaiah