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Interference bias is a major impediment to identifying causal effects in real-world settings. For example, vaccination reduces the transmission of a virus in a population such that everyone benefits -- even those who are not treated. This…

Methodology · Statistics 2025-03-25 Michael O'Riordan , Ciarán M. Gilligan-Lee

We review and conceptualize recent advances in causal inference under network interference, drawing on a complex and diverse body of work that ranges from causal inference, statistical network analysis, economics, the health sciences, and…

Methodology · Statistics 2025-08-12 Subhankar Bhadra , Michael Schweinberger

In settings where interference between units is possible, we define the prevalence of indirect effects to be the number of units who are affected by the treatment of others. This quantity does not fully identify an indirect effect, but may…

Methodology · Statistics 2024-01-18 David Choi

Evaluating the causal health effects of multivariate, continuous exposures, such as air pollution mixtures, is a critical public health challenge. A primary obstacle is the frequent violation of the positivity assumption, which renders the…

Methodology · Statistics 2026-05-05 Zhuochao Huang , Kejin Dong , Tuo Lin , Joseph Antonelli

Estimating causal effects under interference, where the stable unit treatment value assumption is violated, is critical in fields such as regional and public economics. Much of the existing research on causal inference under interference…

Methodology · Statistics 2026-02-03 Akihiro Sato , Shonosuke Sugasawa

We present current methods for estimating treatment effects and spillover effects under "interference", a term which covers a broad class of situations in which a unit's outcome depends not only on treatments received by that unit, but also…

Applications · Statistics 2020-01-16 Peter M. Aronow , Dean Eckles , Cyrus Samii , Stephanie Zonszein

Inferring causal effects from an observational study is challenging because participants are not randomized to treatment. Observational studies in infectious disease research present the additional challenge that one participant's treatment…

Methodology · Statistics 2020-12-25 Brian G. Barkley , Michael G. Hudgens , John D. Clemens , Mohammad Ali , Michael E. Emch

A typical problem in air pollution epidemiology is exposure assessment for individuals for which health data are available. Due to the sparsity of monitoring sites and the limited temporal frequency with which measurements of air pollutants…

Randomized experiments in which the treatment of a unit can affect the outcomes of other units are becoming increasingly common in healthcare, economics, and in the social and information sciences. From a causal inference perspective, the…

Methodology · Statistics 2017-02-14 Daniel L. Sussman , Edoardo M. Airoldi

Here, we explain and illustrate a geometric perspective on causal inference in cohort studies that can help epidemiologists understand the role of standardization in causal inference as well as the distinctions between confounding, effect…

Statistics Theory · Mathematics 2025-06-27 Eben Kenah

Causal inference with interference is a rapidly growing area. The literature has begun to relax the "no-interference" assumption that the treatment received by one individual does not affect the outcomes of other individuals. In this paper…

Methodology · Statistics 2015-03-06 Tyler J. VanderWeele , Eric J. Tchetgen Tchetgen , M. Elizabeth Halloran

An important problem in econometrics and marketing is to infer the causal impact that a designed market intervention has exerted on an outcome metric over time. This paper proposes to infer causal impact on the basis of a…

Applications · Statistics 2015-06-02 Kay H. Brodersen , Fabian Gallusser , Jim Koehler , Nicolas Remy , Steven L. Scott

Estimating effects of spatially structured exposures is complicated by unmeasured spatial confounders, which undermine identifiability in spatial linear regression models unless structural assumptions are imposed. We develop a general…

Methodology · Statistics 2025-12-30 Anik Burman , Elizabeth L. Ogburn , Abhirup Datta

In this paper, we propose a robust method to estimate the average treatment effects in observational studies when the number of potential confounders is possibly much greater than the sample size. We first use a class of penalized…

Methodology · Statistics 2018-12-21 Yang Ning , Sida Peng , Kosuke Imai

One core assumption typically adopted for valid causal inference is that of no interference between experimental units, i.e., the outcome of an experimental unit is unaffected by the treatments assigned to other experimental units. This…

Methodology · Statistics 2025-06-25 Yuki Ohnishi , Bikram Karmakar , Arman Sabbaghi

Semiparametric inference on average causal effects from observational data is based on assumptions yielding identification of the effects. In practice, several distinct identifying assumptions may be plausible; an analyst has to make a…

Methodology · Statistics 2025-10-07 Tetiana Gorbach , Xavier de Luna , Juha Karvanen , Ingeborg Waernbaum

Randomized experiments, or "A/B" tests, remain the gold standard for evaluating the causal effect of a policy intervention or product change. However, experimental settings, such as social networks, where users are interacting and…

Social and Information Networks · Computer Science 2021-02-17 Yuan Yuan , Kristen M. Altenburger , Farshad Kooti

Causal inference is crucial for understanding the true impact of interventions, policies, or actions, enabling informed decision-making and providing insights into the underlying mechanisms that shape our world. In this paper, we establish…

Methodology · Statistics 2024-03-26 Jingyue Huang , Changbao Wu , Leilei Zeng

A standard assumption for causal inference about the joint effects of time-varying treatment is that one has measured sufficient covariates to ensure that within covariate strata, subjects are exchangeable across observed treatment values,…

Methodology · Statistics 2022-08-04 Andrew Ying , Wang Miao , Xu Shi , Eric J. Tchetgen Tchetgen

We develop a causal inference approach to estimate the number of adverse health events prevented by large-scale air quality regulations via changes in exposure to multiple pollutants. This approach is motivated by regulations that impact…

Applications · Statistics 2019-09-23 Rachel C. Nethery , Fabrizia Mealli , Jason D. Sacks , Francesca Dominici