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Introduction- This paper mainly describes a way to detect with high accuracy patients with early-stage Alzheimer's disease (ES-AD) versus healthy control (HC) subjects, from datasets built with handwriting and drawing task records. Method-…

Machine Learning · Computer Science 2021-03-19 Alain Petrowski

This paper investigates the asymptotic behavior of the soft-margin and hard-margin support vector machine (SVM) classifiers for simultaneously high-dimensional and numerous data (large $n$ and large $p$ with $n/p\to\delta$) drawn from a…

Information Theory · Computer Science 2020-03-31 Abla Kammoun , Mohamed-Slim Alouini

The upper motor neuron dysfunction in amyotrophic lateral sclerosis was quantified using triple stimulation and more focal transcranial magnetic stimulation techniques that were developed to reduce recording variability. These measurements…

Neurons and Cognition · Quantitative Biology 2016-09-29 Rahul Remanan , Viktor Sukhotskiy , Mona Shahbazi , Edward P. Furlani , Dale J. Lange

Automated ASD screening tools remain limited by single-architecture evaluations, axis-restricted assessment, and near-exclusive focus on adult cohorts, obscuring age-specific diagnostic patterns critical for early intervention. We introduce…

Machine Learning · Computer Science 2026-05-13 Shubhankit Singh , Hassan Shaikh , Kuldeep Raghuwanshi , Keshav Bulia

Current models on Explainable Artificial Intelligence (XAI) have shown an evident and quantified lack of reliability for measuring feature-relevance when statistically entangled features are proposed for training deep classifiers. There has…

Signal Processing · Electrical Eng. & Systems 2023-02-27 Juan Manuel Mayor-Torres , Sara Medina-DeVilliers , Tessa Clarkson , Matthew D. Lerner , Giuseppe Riccardi

Support vector machines (SVMs) appeared in the early nineties as optimal margin classifiers in the context of Vapnik's statistical learning theory. Since then SVMs have been successfully applied to real-world data analysis problems, often…

Statistics Theory · Mathematics 2016-08-16 Javier M. Moguerza , Alberto Muñoz

Early detection is crucial to prevent the progression of Alzheimer's disease (AD). Thus, specialists can begin preventive treatment as soon as possible. They demand fast and precise assessment in the diagnosis of AD in the earliest and…

Machine Learning · Computer Science 2021-05-19 Alejandro Puente-Castro , Enrique Fernandez-Blanco , Alejandro Pazos , Cristian R. Munteanu

Distance metric learning aims to learn from the given training data a valid distance metric, with which the similarity between data samples can be more effectively evaluated for classification. Metric learning is often formulated as a…

Machine Learning · Computer Science 2015-02-03 Wangmeng Zuo , Faqiang Wang , David Zhang , Liang Lin , Yuchi Huang , Deyu Meng , Lei Zhang

Alzheimer's patients gradually lose their ability to think, behave, and interact with others. Medical history, laboratory tests, daily activities, and personality changes can all be used to diagnose the disorder. A series of time-consuming…

Machine Learning · Computer Science 2022-12-02 Md. Sharifur Rahman , Professor Girijesh Prasad

Alzheimer's Disease (AD) is a neurodegenerative disease affecting millions of individuals across the globe. As the prevalence of this disease continues to rise, early diagnosis is crucial to improve clinical outcomes. Neural networks,…

Image and Video Processing · Electrical Eng. & Systems 2024-09-06 Akshay Sunkara , Rajiv Morthala , Anav Jain , Srinjoy Ghose , Santosh Morthala

The cerebrospinal fluid (CSF) of 19 subjects who received a clinical diagnosis of Alzheimer's disease (AD) as well as of 5 pathological controls have been collected and analysed by Raman spectroscopy (RS). We investigated whether the raw…

Alzheimer's Disease (AD) detection employs machine learning classification models to distinguish between individuals with AD and those without. Different from conventional classification tasks, we identify within-class variation as a…

Audio and Speech Processing · Electrical Eng. & Systems 2025-09-29 Jiawen Kang , Dongrui Han , Lingwei Meng , Jingyan Zhou , Jinchao Li , Xixin Wu , Helen Meng

Resting-state functional MRI (rs-fMRI) scans hold the potential to serve as a diagnostic or prognostic tool for a wide variety of conditions, such as autism, Alzheimer's disease, and stroke. While a growing number of studies have…

Computer Vision and Pattern Recognition · Computer Science 2018-06-14 Meenakshi Khosla , Keith Jamison , Amy Kuceyeski , Mert Sabuncu

Autism Spectrum Disorder significantly influences the communication abilities, learning processes, behavior, and social interactions of individuals. Although early intervention and customized educational strategies are critical to improving…

Machine Learning · Computer Science 2025-10-10 Nelaka K. A. R , Peiris M. K. , Liyanage R. P. B

Support vector data description (SVDD) is a popular anomaly detection technique. The SVDD classifier partitions the whole data space into an inlier region, which consists of the region near the training data, and an outlier region, which…

Machine anomalous sound detection (ASD) is a valuable technique across various applications. However, its generalization performance is often limited due to challenges in data collection and the complexity of acoustic environments. Inspired…

Sound · Computer Science 2025-08-19 Bing Han , Anbai Jiang , Xinhu Zheng , Wei-Qiang Zhang , Jia Liu , Pingyi Fan , Yanmin Qian

In this article, we introduce a novel problem of audio-visual autism behavior recognition, which includes social behavior recognition, an essential aspect previously omitted in AI-assisted autism screening research. We define the task at…

Anatomical brain parcellations dominate rs-fMRI-based Autism Spectrum Disorder (ASD) classification, yet their rigid boundaries may fail to capture the idiosyncratic connectivity patterns that characterise ASD. We present a graph-based deep…

Computer Vision and Pattern Recognition · Computer Science 2026-03-04 Syeda Hareem Madani , Noureen Bibi , Adam Rafiq Jeraj , Sumra Khan , Anas Zafar , Rizwan Qureshi

Speech Sound Disorders (SSD) affect roughly five percent of children, yet speech-language pathologists face severe staffing shortages and unmanageable caseloads. We test a hierarchical approach to SSD classification on the granular…

Computation and Language · Computer Science 2026-04-30 Darren Fürst , Sebastian Steindl , Ulrich Schäfer

The rise of Alzheimers Disease worldwide has prompted a search for efficient tools which can be used to predict deterioration in cognitive decline leading to dementia. In this paper, we explore the potential of survival machine learning as…

Machine Learning · Computer Science 2023-06-21 Henry Musto , Daniel Stamate , Ida Pu , Daniel Stahl