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Note: The final version of this article was published in Computers and Geosciences, Volume 206, January 2026, 106038. DOI: 10.1016/j.cageo.2025.106038. Readers should refer to the published version for the most up-to-date content.…

The design of porous infill structures presents significant challenges due to their complex geometric configurations, such as the accurate representation of geometric boundaries and the control of localized maximum stress. In current…

Optimization and Control · Mathematics 2025-10-14 Shuzhi Xu , Hiroki Kawabe , Kentaro Yaji

We present a new approach and an algorithm for optimizing the material configuration and behaviour of a fluid saturated porous medium in a two-scale setting. The state problem is governed by the Biot model describing the fluid-structure…

Computational Engineering, Finance, and Science · Computer Science 2023-01-30 Bich Ngoc Vu , Vladimir Lukeš , Michael Stingl , Eduard Rohan

In traditional topology optimization, the computing time required to iteratively update the material distribution within a design domain strongly depends on the complexity or size of the problem, limiting its application in real engineering…

Computational Engineering, Finance, and Science · Computer Science 2024-05-14 Gabriel Garayalde , Matteo Torzoni , Matteo Bruggi , Alberto Corigliano

Camouflaged objects are typically assimilated into their backgrounds and exhibit fuzzy boundaries. The complex environmental conditions and the high intrinsic similarity between camouflaged targets and their surroundings pose significant…

Computer Vision and Pattern Recognition · Computer Science 2023-06-07 Tianyou Chen , Jin Xiao , Xiaoguang Hu , Guofeng Zhang , Shaojie Wang

We propose a multiscale mechanobiological model of bone remodelling to investigate the site-specific evolution of bone volume fraction across the midshaft of a femur. The model includes hormonal regulation and biochemical coupling of bone…

Tissues and Organs · Quantitative Biology 2016-05-13 C. Lerebours , P. R. Buenzli , S. Scheiner , P. Pivonka

We consider a strongly heterogeneous medium saturated by an incompressible viscous fluid as it appears in geomechanical modeling. This poroelasticity problem suffers from rapidly oscillating material parameters, which calls for a thorough…

Numerical Analysis · Mathematics 2018-12-27 Robert Altmann , Eric Chung , Roland Maier , Daniel Peterseim , Sai-Mang Pun

Progresses in additive manufacturing technologies allow the realization of finely graded microstructured materials with tunable mechanical properties. This paves the way to a wealth of innovative applications, calling for the combined…

Analysis of PDEs · Mathematics 2023-07-10 Stefano Almi , Ulisse Stefanelli

Critically sized defects are currently treated via autologous or allograft bone grafting, distraction osteogenesis, and membrane induction. However, these methods have major weaknesses which encourage the development of synthetic bone graft…

Tissues and Organs · Quantitative Biology 2018-07-17 Rebecca Chung , Dilhan M. Kalyon , Antonio Valdevit

This paper concerns a space-time homogenization limit of nonnegative weak solutions to porous medium equations. In particular, the so-called homogenized matrix will be characterized in terms of solutions to cell problems, which drastically…

Analysis of PDEs · Mathematics 2021-11-11 Goro Akagi , Tomoyuki Oka

Although various structural optimization techniques have a sound mathematical basis, the practical constructability of optimal designs poses a great challenge in the manufacturing stage. Currently, there is only a limited number of unified…

Numerical Analysis · Mathematics 2024-07-19 Lowhikan Sivanantha Sarma , Chinthaka Mallikarachchi , Sumudu Herath

The tenfold classification provides a powerful framework for organizing topological phases of matter based on symmetry and spatial dimension. However, it does not offer a systematic method for transitioning between classes or engineering…

Mesoscale and Nanoscale Physics · Physics 2025-08-08 Amit Goft , Eric Akkermans

Topology optimization enables the design of highly efficient and complex structures, but conventional iterative methods, such as SIMP-based approaches, often suffer from high computational costs and sensitivity to initial conditions.…

Computational Engineering, Finance, and Science · Computer Science 2025-09-18 Aaron Lutheran , Srijan Das , Alireza Tabarraei

The microstructure analyses of porous media have considerable research value for the study of macroscopic properties. As the premise of conducting these analyses, the accurate reconstruction of microstructure digital model is also an…

Image and Video Processing · Electrical Eng. & Systems 2023-04-26 Zhenchuan Ma , Xiaohai He , Pengcheng Yan , Fan Zhang , Qizhi Teng

Microstructure reconstruction is a key enabler of process-structure-property linkages, a central topic in materials engineering. Revisiting classical optimization-based reconstruction techniques,they are recognized as a powerful framework…

Materials Science · Physics 2021-03-19 Paul Seibert , Marreddy Ambati , Alexander Raßloff , Markus Kästner

Pharmaceutical treatments can slow bone degradation, thus reducing the fracture risk inherent in osteoporosis. Antiresorptive treatments block the over-activation of osteoclasts vs osteoblasts, but the resulting decrease in bone remodeling…

Medical Physics · Physics 2021-12-20 Jean-Louis Milan , Chan Yone Claudia , Rossi Jean-Marie , Chabrand Patrick

Porous structures such as trabecular bone are widely seen in nature. These structures exhibit superior mechanical properties whilst being lightweight. In this paper, we present a method to generate bone-like porous structures as lightweight…

Graphics · Computer Science 2018-05-01 Jun Wu , Niels Aage , Ruediger Westermann , Ole Sigmund

Construction of a scaffold structure that supports a desired motif, conferring protein function, shows promise for the design of vaccines and enzymes. But a general solution to this motif-scaffolding problem remains open. Current…

Biomolecules · Quantitative Biology 2023-03-21 Brian L. Trippe , Jason Yim , Doug Tischer , David Baker , Tamara Broderick , Regina Barzilay , Tommi Jaakkola

The behavior of materials is influenced by a wide range of phenomena occurring across various time and length scales. To better understand the impact of microstructure on macroscopic response, multiscale modeling strategies are essential.…

In the present paper, the material parameters of the isotropic relaxed micromorphic model derived for a specific metamaterial in a previous contribution are used to model its transmission properties. Specifically, the reflection and…

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