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Expectation maximisation (EM) is an unsupervised learning method for estimating the parameters of a finite mixture distribution. It works by introducing "hidden" or "latent" variables via Baum's auxiliary function $Q$ that allow the joint…

Machine Learning · Computer Science 2022-05-19 Graham W. Pulford

Brain tumors are abnormalities that can severely impact a patient's health, leading to life-threatening conditions such as cancer. These can result in various debilitating effects, including neurological issues, cognitive impairment, motor…

Image and Video Processing · Electrical Eng. & Systems 2024-09-04 Pandiyaraju V , Shravan Venkatraman , Abeshek A , Pavan Kumar S , Aravintakshan S A

The Extreme Learning Machine (ELM) technique is a machine learning approach for constructing feed-forward neural networks with a single hidden layer and their models. The ELM model can be constructed while being trained by concurrently…

Optimization and Control · Mathematics 2024-01-30 Muideen Adegoke , Lateef O. Jolaoso , Mardiyyah Oduwole

Brain tumors are serious health problems that require early diagnosis due to their high mortality rates. Diagnosing tumors by examining Magnetic Resonance Imaging (MRI) images is a process that requires expertise and is prone to error.…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Mustafa Yurdakul , Şakir Taşdemir

Glioblastoma (GBM) is one of the most aggressive and lethal human cancers. Intra-tumoral genetic heterogeneity poses a significant challenge for treatment. Biopsy is invasive, which motivates the development of non-invasive, MRI-based…

Gliomas are the most prevalent type of primary brain tumors, and their accurate segmentation from MRI is critical for diagnosis, treatment planning, and longitudinal monitoring. However, the scarcity of high-quality annotated imaging data…

The objective of this study was to develop a PET tumor-segmentation framework that addresses the challenges of limited spatial resolution, high image noise, and lack of clinical training data with ground-truth tumor boundaries in PET…

Background and Purpose: Pediatric low-grade glioma (pLGG) is the most common type of brain tumor in children, and identification of molecular markers for pLGG is crucial for successful treatment planning. Convolutional Neural Network (CNN)…

Computer Vision and Pattern Recognition · Computer Science 2023-10-26 Khashayar Namdar , Matthias W. Wagner , Kareem Kudus , Cynthia Hawkins , Uri Tabori , Brigit Ertl-Wagner , Farzad Khalvati

Supervised anomaly detection methods perform well in identifying known anomalies that are well represented in the training set. However, they often struggle to generalise beyond the training distribution due to decision boundaries that lack…

Machine Learning · Computer Science 2025-11-18 Zahra Zamanzadeh Darban , Qizhou Wang , Charu C. Aggarwal , Geoffrey I. Webb , Ehsan Abbasnejad , Mahsa Salehi

We propose a fine-tuning algorithm for brain tumor segmentation that needs only a few data samples and helps networks not to forget the original tasks. Our approach is based on active learning and meta-learning. One of the difficulties in…

Image and Video Processing · Electrical Eng. & Systems 2023-05-17 Seungyub Han , Yeongmo Kim , Seokhyeon Ha , Jungwoo Lee , Seunghong Choi

Glioblastoma is a highly aggressive and malignant brain tumor type that requires early diagnosis and prompt intervention. Due to its heterogeneity in appearance, developing automated detection approaches is challenging. To address this…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Ziya Ata Yazıcı , İlkay Öksüz , Hazım Kemal Ekenel

Glioma constitutes 80% of malignant primary brain tumors and is usually classified as HGG and LGG. The LGG tumors are less aggressive, with slower growth rate as compared to HGG, and are responsive to therapy. Tumor biopsy being challenging…

Computer Vision and Pattern Recognition · Computer Science 2019-03-25 Subhashis Banerjee , Sushmita Mitra , Francesco Masulli , Stefano Rovetta

Meningiomas represent the most prevalent form of primary brain tumors, comprising nearly one-third of all diagnosed cases. Accurate delineation of these tumors from MRI scans is crucial for guiding treatment strategies, yet remains a…

Image and Video Processing · Electrical Eng. & Systems 2025-10-27 Mohammad Mahdi Danesh Pajouh , Sara Saeedi

Extreme learning machine (ELM) is an extremely fast learning method and has a powerful performance for pattern recognition tasks proven by enormous researches and engineers. However, its good generalization ability is built on large numbers…

Machine Learning · Computer Science 2015-02-05 Wentao Zhu , Jun Miao , Laiyun Qing

Using multimodal Magnetic Resonance Imaging (MRI) is necessary for accurate brain tumor segmentation. The main problem is that not all types of MRIs are always available in clinical exams. Based on the fact that there is a strong…

Image and Video Processing · Electrical Eng. & Systems 2021-11-11 Tongxue Zhou , Stéphane Canu , Pierre Vera , Su Ruan

Nuclei segmentation is a fundamental task in histopathology image analysis. Typically, such segmentation tasks require significant effort to manually generate accurate pixel-wise annotations for fully supervised training. To alleviate such…

Computer Vision and Pattern Recognition · Computer Science 2020-07-13 Hui Qu , Pengxiang Wu , Qiaoying Huang , Jingru Yi , Zhennan Yan , Kang Li , Gregory M. Riedlinger , Subhajyoti De , Shaoting Zhang , Dimitris N. Metaxas

Accurate detection and segmentation of brain tumors from magnetic resonance imaging (MRI) are essential for diagnosis, treatment planning, and clinical monitoring. While convolutional architectures such as U-Net have long been the backbone…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Arman Behnam

Brain tumors are one of the most common and dangerous neurological diseases which require a timely and correct diagnosis to provide the right treatment procedures. Even with the promotion of magnetic resonance imaging (MRI), the process of…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Md. Srabon Chowdhury , Syeda Fahmida Tanzim , Sheekar Banerjee , Ishtiak Al Mamoon , AKM Muzahidul Islam

We present a novel formulation for the calibration of a biophysical tumor growth model from a single-time snapshot, MRI scan of a glioblastoma patient. Tumor growth models are typically nonlinear parabolic partial differential equations…

Quantitative Methods · Quantitative Biology 2020-06-30 Klaudius Scheufele , Shashank Subramanian , Andreas Mang , George Biros , Miriam Mehl

The scarcity of labeled data often limits the application of supervised deep learning techniques for medical image segmentation. This has motivated the development of semi-supervised techniques that learn from a mixture of labeled and…

Computer Vision and Pattern Recognition · Computer Science 2019-11-05 Gerda Bortsova , Florian Dubost , Laurens Hogeweg , Ioannis Katramados , Marleen de Bruijne