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Statistical models for families of evolutionary related proteins have recently gained interest: in particular pairwise Potts models, as those inferred by the Direct-Coupling Analysis, have been able to extract information about the…

Biomolecules · Quantitative Biology 2019-09-25 Kai Shimagaki , Martin Weigt

Medical image segmentation plays a vital role in various clinical applications, enabling accurate delineation and analysis of anatomical structures or pathological regions. Traditional CNNs have achieved remarkable success in this field.…

Image and Video Processing · Electrical Eng. & Systems 2024-04-18 Seyed M. R. Modaresi , Aomar Osmani , Mohammadreza Razzazi , Abdelghani Chibani

Accurate classification of molecular chemical motifs from experimental measurement is an important problem in molecular physics, chemistry and biology. In this work, we present neural network ensemble classifiers for predicting the presence…

Materials Science · Physics 2023-06-29 Matthew R. Carbone , Phillip M. Maffettone , Xiaohui Qu , Shinjae Yoo , Deyu Lu

User financial default prediction plays a critical role in credit risk forecasting and management. It aims at predicting the probability that the user will fail to make the repayments in the future. Previous methods mainly extract a set of…

Risk Management · Quantitative Finance 2024-03-12 Daixin Wang , Zhiqiang Zhang , Yeyu Zhao , Kai Huang , Yulin Kang , Jun Zhou

Motivation: Detecting local correlations in expression between neighbor genes along the genome has proved to be an effective strategy to identify possible causes of transcriptional deregulation in cancer. It has been successfully used to…

Convolutional Neural Networks (CNNs) work very well for supervised learning problems when the training dataset is representative of the variations expected to be encountered at test time. In medical image segmentation, this premise is…

Image and Video Processing · Electrical Eng. & Systems 2021-01-26 Neerav Karani , Ertunc Erdil , Krishna Chaitanya , Ender Konukoglu

Motivation: Genome and Proteome Alignments, represented by the Multiple Alignment File (MAF) format, have become a standard approach in the field of comparative genomics and proteomics. However, current approaches lack a direct method for…

This study describes a procedure for applying causal modeling to detect and mitigate algorithmic bias in a multiclass classification problem. The dataset was derived from the FairFace dataset, supplemented with emotional labels generated by…

Machine Learning · Computer Science 2025-01-15 Min Sik Byun , Wendy Wan Yee Hui , Wai Kwong Lau

Extracting stimulus features from neuronal ensembles is of great interest to the development of neuroprosthetics that project sensory information directly to the brain via electrical stimulation. Machine learning strategies that optimize…

Neurons and Cognition · Quantitative Biology 2020-09-08 Vivek Subramanian , Joshua Khani

Accurately assigning folds for divergent protein sequences is a major obstacle to structural studies and underlies the inverse protein folding problem. Herein, we outline our theories for fold-recognition in the "twilight-zone" of sequence…

Quantitative Methods · Quantitative Biology 2010-08-31 Yoojin Hong , Kyung Dae Ko , Gaurav Bhardwaj , Zhenhai Zhang , Damian B. van Rossum , Randen L. Patterson

Time series prediction is of great significance in many applications and has attracted extensive attention from the data mining community. Existing work suggests that for many problems, the shape in the current time series may correlate an…

Artificial Intelligence · Computer Science 2017-12-05 Yuanduo He , Xu Chu , Juguang Peng , Jingyue Gao , Yasha Wang

Cardiac indices estimation is of great importance during identification and diagnosis of cardiac disease in clinical routine. However, estimation of multitype cardiac indices with consistently reliable and high accuracy is still a great…

Computer Vision and Pattern Recognition · Computer Science 2017-05-29 Wufeng Xue , Ali Islam , Mousumi Bhaduri , Shuo Li

Automated segmentation of individual calf muscle compartments from 3D magnetic resonance (MR) images is essential for developing quantitative biomarkers for muscular disease progression and its prediction. Achieving clinically acceptable…

Image and Video Processing · Electrical Eng. & Systems 2020-12-23 Zhihui Guo , Honghai Zhang , Zhi Chen , Ellen van der Plas , Laurie Gutmann , Daniel Thedens , Peggy Nopoulos , Milan Sonka

Graph neural networks (GNNs) have emerged as powerful tools for learning protein structures by capturing spatial relationships at the residue level. However, existing GNN-based methods often face challenges in learning multiscale…

Machine Learning · Computer Science 2026-02-03 Shih-Hsin Wang , Yuhao Huang , Taos Transue , Justin Baker , Jonathan Forstater , Thomas Strohmer , Bao Wang

Metagenomics characterizes the taxonomic diversity of microbial communities by sequencing DNA directly from an environmental sample. One of the main challenges in metagenomics data analysis is the binning step, where each sequenced read is…

Quantitative Methods · Quantitative Biology 2015-05-27 Kévin Vervier , Pierre Mahé , Maud Tournoud , Jean-Baptiste Veyrieras , Jean-Philippe Vert

The identification of motifs--subgraphs that appear significantly more often in a particular network than in an ensemble of randomized networks--has become a ubiquitous method for uncovering potentially important subunits within networks…

Molecular Networks · Quantitative Biology 2010-08-27 Reid Ginoza , Andrew Mugler

We develop a novel deep contour detection algorithm with a top-down fully convolutional encoder-decoder network. Our proposed method, named TD-CEDN, solves two important issues in this low-level vision problem: (1) learning multi-scale and…

Computer Vision and Pattern Recognition · Computer Science 2017-07-13 Yahui Liu , Jian Yao , Li Li , Xiaohu Lu , Jing Han

The presence of certain clinical dermoscopic features within a skin lesion may indicate melanoma, and automatically detecting these features may lead to more quantitative and reproducible diagnoses. We reformulate the task of classifying…

Computer Vision and Pattern Recognition · Computer Science 2019-03-28 Jeremy Kawahara , Ghassan Hamarneh

In the age of social computing, finding interesting network patterns or motifs is significant and critical for various areas such as decision intelligence, intrusion detection, medical diagnosis, social network analysis, fake news…

Social and Information Networks · Computer Science 2022-04-07 Shuo Yu , Feng Xia , Yuchen Sun , Tao Tang , Xiaoran Yan , Ivan Lee

Time series motifs play an important role in the time series analysis. The motif-based time series clustering is used for the discovery of higher-order patterns or structures in time series data. Inspired by the convolutional neural network…

Machine Learning · Computer Science 2020-01-22 Yadong Zhang , Xin Chen
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