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Operation management of nuclear power plants consists of several computationally hard problems. Searching for an in-core fuel loading pattern is among them. The main challenge of this combinatorial optimization problem is the exponential…

Quantum annealing technologies aim to solve computational optimization and sampling problems. QPU (Quantum Processing Unit) machines such as the D-Wave system use the QUBO (Quadratic Unconstrained Binary Optimization) formula to define…

Quantum Physics · Physics 2022-03-28 Toufan D. Tambunan , Andriyan B. Suksmono , Ian J. M. Edward , Rahmat Mulyawan

Computed tomography (CT) is an important imaging technique used in medical analysis of the internal structure of the human body. Previously, image segmentation methods were required after acquiring reconstructed CT images to obtain…

Quantum Physics · Physics 2024-09-17 Kyungtaek Jun

The Quantum Approximate Optimization Algorithm (QAOA) is a quantum algorithm that finds approximate solutions to problems in combinatorial optimization, especially those that can be formulated as a Quadratic Unconstrained Binary…

Quantum Physics · Physics 2025-09-23 Bikrant Bhattacharyya , Michael Capriotti , Reuben Tate

A quantum annealer heuristically minimizes quadratic unconstrained binary optimization (QUBO) problems, but is limited by the physical hardware in the size and density of the problems it can handle. We have developed a meta-heuristic solver…

Discrete Mathematics · Computer Science 2016-05-20 Gili Rosenberg , Mohammad Vazifeh , Brad Woods , Eldad Haber

This article describes how to solve Sudoku puzzles using Quadratic Unconstrained Binary Optimization (QUBO). To this end, a QUBO instance with 729 variables is constructed, encoding a Sudoku grid with all constraints in place, which is then…

Quantum Physics · Physics 2024-03-11 Sascha Mücke

Many organizations that vitally depend on computation for their competitive advantage are keen to exploit the expected performance of quantum computers (QCs) as soon as quantum advantage is achieved. The best approach to deliver hardware…

Quantum optimization is the most mature quantum computing technology to date, providing a promising approach towards efficiently solving complex combinatorial problems. Methods such as adiabatic quantum computing (AQC) have been employed in…

The searching efficiency of the quantum approximate optimization algorithm is dependent on both the classical and quantum sides of the algorithm. Recently a quantum approximate Bayesian optimization algorithm (QABOA) that includes two…

Quantum Physics · Physics 2023-10-25 Jungin E. Kim , Yan Wang

Quantum annealing (QA) has the potential to significantly improve solution quality and reduce time complexity in solving combinatorial optimization problems compared to classical optimization methods. However, due to the limited number of…

Quantum Physics · Physics 2025-04-09 Seongmin Kim , Sang-Woo Ahn , In-Saeng Suh , Alexander W. Dowling , Eungkyu Lee , Tengfei Luo

This paper develops an algorithmic solution using Ising machines to solve large-scale higher-order binary optimization (HOBO) problems with inequality constraints for resource optimization in wireless communications systems. Quadratic…

Information Theory · Computer Science 2025-09-25 Gan Zheng , Ioannis Krikidis

In experimental High-Energy Physics, unfolding refers to the problem of estimating the underlying distribution of a physical observable from detector-level data, in the presence of statistical fluctuations and systematic uncertainties.…

Quantum Physics · Physics 2026-05-13 Simone Gasperini , Gianluca Bianco , Marco Lorusso , Carla Rieger , Michele Grossi

Neural network pruning can be formulated as a combinatorial optimization problem, yet most existing approaches rely on greedy heuristics that ignore complex interactions between filters. Formal optimization methods such as Quadratic…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Osama Orabi , Artur Zagitov , Hadi Salloum , Viktor A. Lobachev , Kasymkhan Khubiev , Yaroslav Kholodov

To run an algorithm on a quantum computer, one must choose an assignment from logical qubits in a circuit to physical qubits on quantum hardware. This task of initial qubit placement, or qubit allocation, is especially important on…

Quantum Physics · Physics 2020-12-01 Bryan Dury , Olivia Di Matteo

The maximum-cut problem is one of the fundamental problems in combinatorial optimization. With the advent of quantum computers, both the maximum-cut and the equivalent quadratic unconstrained binary optimization problem have experienced…

Optimization and Control · Mathematics 2022-02-07 Daniel Rehfeldt , Thorsten Koch , Yuji Shinano

In the pursuit of achieving near-term quantum advantage for combinatorial optimization problems, the Quantum Approximate Optimization Algorithm (QAOA) and the Variational Quantum Eigensolver (VQE) are the primary methods of interest, but…

Quantum Physics · Physics 2025-03-06 Adelina Bärligea , Benedikt Poggel , Jeanette Miriam Lorenz

Quantum annealing is a method developed to solve combinatorial optimization problems by utilizing quantum bits. Solving such problems corresponds to minimizing a cost function defined over binary variables. However, in many practical cases,…

Quantum Physics · Physics 2025-06-26 Seiya Endo , Shohei Kawakatsu , Hiromichi Matsuyama , Kohei Suzuki , Yuichiro Matsuzaki

This article describes an improved brute-force solving strategy for Quadratic Unconstrained Binary Optimization (QUBO) problems that is faster than naive approaches and easily parallelizable. It exploits the Gray code ordering of natural…

Data Structures and Algorithms · Computer Science 2023-10-31 Sascha Mücke

We propose and evaluate a quantum-inspired algorithm for solving Quadratic Unconstrained Binary Optimization (QUBO) problems, which are mathematically equivalent to finding ground states of Ising spin-glass Hamiltonians. The algorithm…

Artificial Intelligence · Computer Science 2025-10-24 Max B. Zhao , Fei Li

As contemporary quantum computers do not possess error correction, any calculation performed by these devices can be considered an involuntary approximation. To solve a problem on a quantum annealer, it has to be expressed as an instance of…