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Photoacoustic tomography seeks to reconstruct an acoustic initial pressure distribution from the measurement of the ultrasound waveforms. Conventional methods assume a-prior knowledge of the sound speed distribution, which practically is…

Image and Video Processing · Electrical Eng. & Systems 2019-09-16 Hongming Shan , Christopher Wiedeman , Ge Wang , Yang Yang

The reconstruction task in photoacoustic tomography can vary a lot depending on measured targets, geometry, and especially the quantity we want to recover. Specifically, as the signal is generated due to the coupling of light and sound by…

Medical Physics · Physics 2023-11-28 Andreas Hauptmann , Tanja Tarvainen

Photoacoustic computed tomography (PACT), also known as optoacoustic tomography, is an emerging imaging technique that holds great promise for biomedical imaging. PACT is a hybrid imaging method that can exploit the strong endogenous…

Medical Physics · Physics 2019-05-13 Joemini Poudel , Yang Lou , Mark A. Anastasio

Photo-acoustic tomography (PAT) aims to leverage the photo-acoustic coupling between optical absorption of light sources and ultrasound (US) emission to obtain high contrast reconstructions of optical parameters with the high resolution of…

Analysis of PDEs · Mathematics 2016-09-21 Guillaume Bal , Amir Moradifam

Photoacoustic(PA) imaging is a non-destructive and non-invasive technology for visualizing minute blood vessel structures in the body using ultrasonic sensors. In PA imaging, the image quality of a single-shot image is poor, and it is…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Tatsuhiro Eguchi , Shumpei Takezaki , Mihoko Shimano , Takayuki Yagi , Ryoma Bise

Photoacoustic Tomography (PAT) is an emerging biomedical "imaging from coupled physics" technique, in which the image contrast is due to optical absorption, but the information is carried to the surface of the tissue as ultrasound pulses.…

Numerical Analysis · Mathematics 2016-11-03 Simon R. Arridge , Marta M. Betcke , Ben T. Cox , Felix Lucka , Brad E. Treeby

The combination of microfluidic technology and optical fluids characterization techniques has been recently applied to produce lab-on-a-chip systems. In the present work, bringing together the imaging technique called photoacoustic imaging…

Photoacoustic imaging (PAI), by combining high optical contrast with ultrasonic resolution, offers a promising noninvasive approach for dynamic monitoring of cerebral vasculature. However, transcranial PAI still faces significant challenges…

Image sensors are the backbone of many imaging technologies of great importance to modern sciences, being particularly relevant in biomedicine. An ideal image sensor should be usable through all the electromagnetic spectrum (large…

Medical Physics · Physics 2022-03-16 Juan Aguirre

Photoacoustic tomography (PAT) and thermoacoustic tomography (TAT) both leverage acoustic signals generated by electromagnetic absorption to noninvasively image deep tissues. PAT operates by detecting optical absorption, whereas TAT targets…

Optics · Physics 2026-03-09 Skyler P. Selvin , XuanHao Wang , Handi Deng , Bohua Chen , Cheng Ma

The in vivo propulsion and monitoring of nanoparticles (NPs) have received tremendous achievements in the past decade. Developing functional NPs that can be efficiently manipulated inside the human body with a non-invasive tracking modality…

Biological Physics · Physics 2024-10-07 Jiayan Li , Chang Xu , Yingna Chen , Junmei Cao , Wanli Ye , Yu Cheng , Qian Cheng

Elastographic imaging is a widely used technique which can in principle be implemented on top of every imaging modality. In elastography, the specimen is exposed to a force causing local displacements in the probe, and imaging is performed…

Optimization and Control · Mathematics 2014-07-28 Thomas Glatz , Otmar Scherzer , Thomas Widlak

We present a photoacoustic computed tomography investigation on a healthy human finger, to image blood vessels with a focus on vascularity across the interphalangeal joints. The cross-sectional images were acquired using an imager…

In photoacoustic tomography (PAT), a hybrid imaging modality that is based on the acoustic detection of optical absorption from biological tissue exposed to a pulsed laser, a short pulse laser generates an initial pressure proportional to…

Numerical Analysis · Mathematics 2026-03-27 Sunghwan Moon , Anwesa Dey , Souvik Roy

Over the past decade, optical wavefront shaping has been developed to focus light through highly opaque scattering layers, opening new possibilities for biomedical applications. To probe light intensity deep inside soft scattering media…

Optics · Physics 2025-08-25 Fei Xia , Ivo Leite , Robert Prevedel , Thomas Chaigne

Fluorescence microscopic imaging in centimeter-deep tissue has been highly sought-after for many years because much interesting in vivo micro-information, such as microcirculation, tumor angiogenesis, and metastasis, may deeply locate in…

Photoacoustic tomography (PAT) is a newly developed medical imaging modality, which combines the advantages of pure optical imaging and ultrasound imaging, owning both high optical contrast and deep penetration depth. Very recently, PAT is…

Medical Physics · Physics 2021-09-21 Tengbo Lyu , Jiadong Zhang , Zijian Gao , Changchun Yang , Feng Gao , Fei Gao

We implement the photoacoustic transmission-matrix approach on a two-dimensional photoacoustic imaging system, using a 15 MHz linear ultrasound array. Using a black leaf skeleton as a complex absorbing structure, we demonstrate that the…

Optics · Physics 2017-11-15 Thomas Chaigne , Jerome Gateau , Ori Katz , Emmanuel Bossy , Sylvain Gigan

This paper is devoted to the modelization of the photoacoustic effect generated by the electromagnetic heating of metallic nanoparticles embedded in a biological tissue. We first derive an asymptotic models for the plasmonic resonances and…

Mathematical Physics · Physics 2017-01-24 Faouzi Triki , Margaux Vauthrin

In the field of biomedical imaging, ultrasonography has become increasingly widespread, and an important auxiliary diagnostic tool with unique advantages, such as being non-ionising and often portable. This article reviews the…

Signal Processing · Electrical Eng. & Systems 2022-11-08 Tianqi Yang , Oktay Karakuş , Nantheera Anantrasirichai , Alin Achim