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An automated segmentation and classification of nuclei is an essential task in digital pathology. The current deep learning-based approaches require a vast amount of annotated datasets by pathologists. However, the existing datasets are…

Image and Video Processing · Electrical Eng. & Systems 2022-10-25 Tan Nhu Nhat Doan , Kyungeun Kim , Boram Song , Jin Tae Kwak

Glomeruli are histological structures of the kidney cortex formed by interwoven blood capillaries, and are responsible for blood filtration. Glomerular lesions impair kidney filtration capability, leading to protein loss and metabolic waste…

Image and Video Processing · Electrical Eng. & Systems 2019-07-02 Paulo Chagas , Luiz Souza , Ikaro Araújo , Nayze Aldeman , Angelo Duarte , Michele Angelo , Washington LC dos-Santos , Luciano Oliveira

The quantitative detection, segmentation, and characterization of glomeruli from high-resolution whole slide imaging (WSI) play essential roles in the computer-assisted diagnosis and scientific research in digital renal pathology.…

Computer Vision and Pattern Recognition · Computer Science 2022-06-02 Tianyuan Yao , Yuzhe Lu , Jun Long , Aadarsh Jha , Zheyu Zhu , Zuhayr Asad , Haichun Yang , Agnes B. Fogo , Yuankai Huo

Segmenting glomerular intraglomerular tissue and lesions traditionally depends on detailed morphological evaluations by expert nephropathologists, a labor-intensive process susceptible to interobserver variability. Our group previously…

Image and Video Processing · Electrical Eng. & Systems 2024-11-27 Lining Yu , Mengmeng Yin , Ruining Deng , Quan Liu , Tianyuan Yao , Can Cui , Junlin Guo , Yu Wang , Yaohong Wang , Shilin Zhao , Haichun Yang , Yuankai Huo

Recognition of glomeruli lesions is the key for diagnosis and treatment planning in kidney pathology; however, the coexisting glomerular structures such as mesangial regions exacerbate the difficulties of this task. In this paper, we…

Image and Video Processing · Electrical Eng. & Systems 2022-03-14 Yang Nan , Fengyi Li , Peng Tang , Guyue Zhang , Caihong Zeng , Guotong Xie , Zhihong Liu , Guang Yang

Recently, the use of circle representation has emerged as a method to improve the identification of spherical objects (such as glomeruli, cells, and nuclei) in medical imaging studies. In traditional bounding box-based object detection,…

Computer Vision and Pattern Recognition · Computer Science 2024-12-02 Jialin Yue , Tianyuan Yao , Ruining Deng , Quan Liu , Juming Xiong , Junlin Guo , Haichun Yang , Yuankai Huo

In this paper, we propose a novel data augmentation technique called GenMix, which combines generative and mixture approaches to leverage the strengths of both methods. While generative models excel at creating new data patterns, they face…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Hansang Lee , Haeil Lee , Helen Hong

Recent studies have demonstrated the diagnostic and prognostic values of global glomerulosclerosis (GGS) in IgA nephropathy, aging, and end-stage renal disease. However, the fine-grained quantitative analysis of multiple GGS subtypes (e.g.,…

Image and Video Processing · Electrical Eng. & Systems 2022-02-02 Yuzhe Lu , Haichun Yang , Zuhayr Asad , Zheyu Zhu , Tianyuan Yao , Jiachen Xu , Agnes B. Fogo , Yuankai Huo

In pathology image analysis, obtaining and maintaining high-quality annotated samples is an extremely labor-intensive task. To overcome this challenge, mixing-based methods have emerged as effective alternatives to traditional preprocessing…

Computer Vision and Pattern Recognition · Computer Science 2023-07-25 Tianyi Zhang , Zhiling Yan , Chunhui Li , Nan Ying , Yanli Lei , Yunlu Feng , Yu Zhao , Guanglei Zhang

Accurate detection of diseased glomeruli is fundamental to progress in renal pathology and underpins the delivery of reliable clinical diagnoses. Although recent advances in computer vision have produced increasingly sophisticated detection…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Tianyu Shi , Xinzi He , Kenji Ikemura , Mert R. Sabuncu , Yihe Yang , Ruining Deng

Data augmentation has become a de facto component of deep learning-based medical image segmentation methods. Most data augmentation techniques used in medical imaging focus on spatial and intensity transformations to improve the diversity…

Image and Video Processing · Electrical Eng. & Systems 2023-08-21 Berke Doga Basaran , Weitong Zhang , Mengyun Qiao , Bernhard Kainz , Paul M. Matthews , Wenjia Bai

Nuclei Segmentation from histology images is a fundamental task in digital pathology analysis. However, deep-learning-based nuclei segmentation methods often suffer from limited annotations. This paper proposes a realistic data augmentation…

Image and Video Processing · Electrical Eng. & Systems 2022-07-01 Yi Lin , Zeyu Wang , Kwang-Ting Cheng , Hao Chen

Automated red blood cell (RBC) classification on blood smear images helps hematologists to analyze RBC lab results in a reduced time and cost. However, overlapping cells can cause incorrect predicted results, and so they have to be…

Image and Video Processing · Electrical Eng. & Systems 2024-10-30 Korranat Naruenatthanaset , Thanarat H. Chalidabhongse , Duangdao Palasuwan , Nantheera Anantrasirichai , Attakorn Palasuwan

Cortical lesions (CLs) have emerged as valuable biomarkers in multiple sclerosis (MS), offering high diagnostic specificity and prognostic relevance. However, their routine clinical integration remains limited due to subtle magnetic…

This study presents an advanced approach to lumbar spine segmentation using deep learning techniques, focusing on addressing key challenges such as class imbalance and data preprocessing. Magnetic resonance imaging (MRI) scans of patients…

Accurate segmentation of glomerulus instances attains high clinical significance in the automated analysis of renal biopsies to aid in diagnosing and monitoring kidney disease. Analyzing real-world histopathology images often encompasses…

Multi-organ segmentation in medical images is a widely researched task and can save much manual efforts of clinicians in daily routines. Automating the organ segmentation process using deep learning (DL) is a promising solution and…

Image and Video Processing · Electrical Eng. & Systems 2024-03-07 Chang Liu , Fuxin Fan , Annette Schwarz , Andreas Maier

The aim of the systematic review was to assess recently published studies on diagnostic test accuracy of glioblastoma treatment response monitoring biomarkers in adults, developed through machine learning (ML). Articles were searched for…

Nuclei instance segmentation is an essential task in pathology image analysis, serving as the foundation for many downstream applications. The release of several public datasets has significantly advanced research in this area, yet many…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Jiamu Wang , Jin Tae Kwak

Background: Accurate lesion segmentation is critical for multiple sclerosis (MS) diagnosis, yet current deep learning approaches face robustness challenges. Aim: This study improves MS lesion segmentation by combining data fusion and deep…

Image and Video Processing · Electrical Eng. & Systems 2025-06-18 Nadezhda Alsahanova , Pavel Bartenev , Maksim Sharaev , Milos Ljubisavljevic , Taleb Al. Mansoori , Yauhen Statsenko
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