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Background: Palliative care is referred to a set of programs for patients that suffer life-limiting illnesses. These programs aim to guarantee a minimum level of quality of life (QoL) for the last stage of life. They are currently based on…

Prediction of mortality in intensive care unit (ICU) patients typically relies on black box models (that are unacceptable for use in hospitals) or hand-tuned interpretable models (that might lead to the loss in performance). We aim to…

Machine Learning · Computer Science 2025-01-09 Chloe Qinyu Zhu , Muhang Tian , Lesia Semenova , Jiachang Liu , Jack Xu , Joseph Scarpa , Cynthia Rudin

Traumatic Brain Injury (TBI) is a major contributor to mortality among older adults, with geriatric patients facing disproportionately high risk due to age-related physiological vulnerability and comorbidities. Early and accurate prediction…

Quantitative Methods · Quantitative Biology 2025-05-23 Yong Si , Junyi Fan , Li Sun , Shuheng Chen , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar

Vital signs are crucial in intensive care units (ICUs). They are used to track the patient's state and to identify clinically significant changes. Predicting vital sign trajectories is valuable for early detection of adverse events.…

Machine Learning · Computer Science 2024-03-28 Bar Eini Porat , Danny Eytan , Uri Shalit

The COVID-19 pandemic has had a considerable impact on day-to-day life. Tackling the disease by providing the necessary resources to the affected is of paramount importance. However, estimation of the required resources is not a trivial…

Image and Video Processing · Electrical Eng. & Systems 2022-05-11 Sai Vidyaranya Nuthalapati , Marcela Vizcaychipi , Pallav Shah , Piotr Chudzik , Chee Hau Leow , Paria Yousefi , Ahmed Selim , Keiran Tait , Ben Irving

Early identification of intensive care patients at risk of in-hospital mortality enables timely intervention and efficient resource allocation. Despite high predictive performance, existing machine learning approaches lack transparency and…

Machine Learning · Computer Science 2025-11-21 Alexander Bakumenko , Janine Hoelscher , Hudson Smith

Patient monitoring is vital in all stages of care. We here report the development and validation of ICU length of stay and mortality prediction models. The models will be used in an intelligent ICU patient monitoring module of an…

Machine Learning · Computer Science 2021-05-11 Khalid Alghatani , Nariman Ammar , Abdelmounaam Rezgui , Arash Shaban-Nejad

Hypertension and atrial fibrillation (AF) often coexist in critically ill patients, significantly increasing mortality rates in the ICU. Early identification of high-risk individuals is crucial for targeted interventions. However, limited…

Applications · Statistics 2025-06-19 Shuheng Chen , Yong Si , Junyi Fan , Li Sun , Greg Placencia , Elham Pishgar , Kamiar Alaei , Maryam Pishgar

Elderly ICU patients with coexisting diabetes mellitus and heart failure experience markedly elevated short-term mortality, yet few predictive models are tailored to this high-risk group. Diabetes mellitus affects nearly 30% of U.S. adults…

Applications · Statistics 2025-06-19 Junyi Fan , Shuheng Chen , Li Sun , Yong Si , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar

Accurate early prediction of in-hospital mortality in intensive care units (ICUs) is essential for timely clinical intervention and efficient resource allocation. This study develops and evaluates machine learning models that integrate both…

Machine Learning · Computer Science 2025-10-22 Nursultan Mamatov , Philipp Kellmeyer

Machine learning models that utilize patient data across time (rather than just the most recent measurements) have increased performance for many risk stratification tasks in the intensive care unit. However, many of these models and their…

Machine Learning · Computer Science 2021-09-24 Nari Johnson , Sonali Parbhoo , Andrew Slavin Ross , Finale Doshi-Velez

Current research efforts largely focus on employing at most one interpretable method to elucidate machine learning (ML) model performance. However, significant barriers remain in translating these interpretability techniques into actionable…

Computers and Society · Computer Science 2025-08-05 Ling Liao , Eva Aagaard

The intensive care unit (ICU) comprises a complex hospital environment, where decisions made by clinicians have a high level of risk for the patients' lives. A comprehensive care pathway must then be followed to reduce p complications.…

Intensive Care Units usually carry patients with a serious risk of mortality. Recent research has shown the ability of Machine Learning to indicate the patients' mortality risk and point physicians toward individuals with a heightened need…

Machine Learning · Computer Science 2025-02-03 Korbinian Randl , Núria Lladós Armengol , Lena Mondrejevski , Ioanna Miliou

Good predictors of ICU Mortality have the potential to identify high-risk patients earlier, improve ICU resource allocation, or create more accurate population-level risk models. Machine learning practitioners typically make choices about…

Artificial Intelligence · Computer Science 2016-02-09 Harini Suresh

Intensive care clinicians need reliable clinical practice tools to preempt unexpected critical events that might harm their patients in intensive care units (ICU), to pre-plan timely interventions, and to keep the patient's family well…

Interpretability of machine learning models is critical for data-driven precision medicine efforts. However, highly predictive models are generally complex and are difficult to interpret. Here using Model-Agnostic Explanations algorithm, we…

Quantitative Methods · Quantitative Biology 2016-10-31 Gajendra Jung Katuwal , Robert Chen

The Intensive Care Unit (ICU) is a hospital department where machine learning has the potential to provide valuable assistance in clinical decision making. Classical machine learning models usually only provide point-estimates and no…

Machine Learning · Computer Science 2024-07-26 David Ruhe , Giovanni Cinà , Michele Tonutti , Daan de Bruin , Paul Elbers

Viewing the trajectory of a patient as a dynamical system, a recurrent neural network was developed to learn the course of patient encounters in the Pediatric Intensive Care Unit (PICU) of a major tertiary care center. Data extracted from…

Machine Learning · Statistics 2017-01-25 M Aczon , D Ledbetter , L Ho , A Gunny , A Flynn , J Williams , R Wetzel

Early recognition of risky trajectories during an Intensive Care Unit (ICU) stay is one of the key steps towards improving patient survival. Learning trajectories from physiological signals continuously measured during an ICU stay requires…

Machine Learning · Computer Science 2019-12-24 Tiago Alves , Alberto Laender , Adriano Veloso , Nivio Ziviani