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The cycle of scientific discovery is frequently bottlenecked by the slow, manual creation of software to support computational experiments\cite{hannay2009how}. To address this, we present Empirical Research Assistance (ERA), an AI system…

With increasing diversity in Deep Neural Network(DNN) models in terms of layer shapes and sizes, the research community has been investigating flexible/reconfigurable accelerator substrates. This line of research has opened up two…

Hardware Architecture · Computer Science 2022-04-26 Ananda Samajdar , Michael Pellauer , Tushar Krishna

Scientific peer review increasingly struggles to assess reproducibility at the scale and complexity of modern research output. Evaluating reproducibility requires reconstructing experimental dependencies, methodological choices, data flows,…

Retrieval-augmented Generation (RAG) extends large language models (LLMs) with external knowledge but faces key challenges: restricted effective context length and redundancy in retrieved documents. Pure compression-based approaches reduce…

Computation and Language · Computer Science 2025-07-09 Yiqiao Jin , Kartik Sharma , Vineeth Rakesh , Yingtong Dou , Menghai Pan , Mahashweta Das , Srijan Kumar

Iterative cycles of theoretical prediction and experimental validation are the cornerstone of the modern scientific method. However, the proverbial "closing of the loop" in experiment-theory cycles in practice are usually ad hoc, often…

Both computational and experimental material discovery bring forth the challenge of exploring multidimensional and multimodal parameter spaces, such as phase diagrams of Hamiltonians with multiple interactions, composition spaces of…

Machine Learning · Computer Science 2024-09-20 Arpan Biswas , Rama Vasudevan , Rohit Pant , Ichiro Takeuchi , Hiroshi Funakubo , Yongtao Liu

Adaptive interventions (AIs) are increasingly becoming popular in medical and behavioral sciences. An AI is a sequence of individualized intervention options that specify for whom and under what conditions different intervention options…

Applications · Statistics 2018-12-18 Palash Ghosh , Inbal Nahum-Shani , Bonnie Spring , Bibhas Chakraborty

We present ScienceClaw + Infinite, a framework for autonomous scientific investigation in which independent agents conduct research without central coordination, and any contributor can deploy new agents into a shared ecosystem. The system…

Artificial Intelligence · Computer Science 2026-03-17 Fiona Y. Wang , Lee Marom , Subhadeep Pal , Rachel K. Luu , Wei Lu , Jaime A. Berkovich , Markus J. Buehler

We study automated test generation for verifying discrete decision-making modules in autonomous systems. We utilize linear temporal logic to encode the requirements on the system under test in the system specification and the behavior that…

Alloy discovery is constrained by vast compositional spaces, competing objectives, and prohibitive experimental costs. Although simulations and machine learning have each accelerated parts of this process, unifying scientific knowledge,…

Current invasive assistive technologies are designed to infer high-dimensional motor control signals from severely paralyzed patients. However, they face significant challenges, including public acceptance, limited longevity, and barriers…

Robotics · Computer Science 2025-05-19 Ali Rabiee , Sima Ghafoori , MH Farhadi , Robert Beyer , Xiangyu Bai , David J Lin , Sarah Ostadabbas , Reza Abiri

High-Throughput materials discovery involves the rapid synthesis, measurement, and characterization of many different but structurally-related materials. A key problem in materials discovery, the phase map identification problem, involves…

Large-scale numerical simulations underpin modern scientific discovery but remain constrained by prohibitive computational costs. AI surrogates offer acceleration, yet adoption in mission-critical settings is limited by concerns over…

Machine Learning · Computer Science 2025-09-30 Dawei Gao , Dali Wang , Zhuowei Gu , Qinglei Cao , Xiao Wang , Peter Thornton , Dan Ricciuto , Yunhe Feng

High throughput experimentation tools, machine learning (ML) methods, and open material databases are radically changing the way new materials are discovered. From the experimentally driven approach in the past, we are moving quickly…

Materials Science · Physics 2025-08-06 Albertus Denny Handoko , Riko I Made

Autonomous labs enable the integration of automated experiment execution, data analysis and decision making. The main challenge remains the integration of diverse data streams from multiple instruments, where the data is often heterogeneous…

Today's scientific challenges, from climate modeling to Inertial Confinement Fusion design to novel material design, require exploring huge design spaces. In order to enable high-impact scientific discovery, we need to scale up our ability…

This paper addresses the gap between the capabilities and utilisation of robotics and automation in laboratory settings and builds upon the concept of Self Driving Labs (SDL). %to significantly impact laboratory operations. We introduce an…

Systems and Control · Electrical Eng. & Systems 2024-02-20 Shayan Azizi , Ehsan Asadi , Shaun Howard , Benjamin W. Muir , Riley O'Shea , Alireza Bab-Hadiashar

Biology has changed radically in the last two decades, transitioning from a descriptive science into a design science. Synthetic biology allows us to bioengineer cells to synthesize novel valuable molecules such as renewable biofuels or…

Quantitative Methods · Quantitative Biology 2021-01-27 Tijana Radivojević , Zak Costello , Kenneth Workman , Hector Garcia Martin

Automatic data augmentation (AutoDA) plays an important role in enhancing the generalization of neural networks. However, mainstream AutoDA methods often encounter two challenges: either the search process is excessively time-consuming,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Anqi Xiao , Weichen Yu , Hongyuan Yu

SARA integrates Eye Tracking and state-of-the-art large language models in a mixed reality framework to enhance the reading experience by providing personalized assistance in real-time. By tracking eye movements, SARA identifies the text…

Human-Computer Interaction · Computer Science 2024-04-11 Enkeleda Thaqi , Mohamed Mantawy , Enkelejda Kasneci