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The paper presents the application of Variational Autoencoders (VAE) for data dimensionality reduction and explorative analysis of mass spectrometry imaging data (MSI). The results confirm that VAEs are capable of detecting the patterns…

Quantitative Methods · Quantitative Biology 2017-08-25 Paolo Inglese , James L. Alexander , Anna Mroz , Zoltan Takats , Robert Glen

The importance weighted autoencoder (IWAE) (Burda et al., 2016) is a popular variational-inference method which achieves a tighter evidence bound (and hence a lower bias) than standard variational autoencoders by optimising a multi-sample…

Machine Learning · Statistics 2019-09-20 Axel Finke , Alexandre H. Thiery

Motivation: Despite advances in the computational analysis of high-throughput molecular profiling assays (e.g. transcriptomics), a dichotomy exists between methods that are simple and interpretable, and ones that are complex but with lower…

Machine Learning · Computer Science 2023-06-12 Pedro Henrique da Costa Avelar , Min Wu , Sophia Tsoka

An assumption-free automatic check of medical images for potentially overseen anomalies would be a valuable assistance for a radiologist. Deep learning and especially Variational Auto-Encoders (VAEs) have shown great potential in the…

Machine Learning · Computer Science 2019-07-12 David Zimmerer , Fabian Isensee , Jens Petersen , Simon Kohl , Klaus Maier-Hein

Medical data sets are usually corrupted by noise and missing data. These missing patterns are commonly assumed to be completely random, but in medical scenarios, the reality is that these patterns occur in bursts due to sensors that are off…

Machine Learning · Computer Science 2021-11-09 Daniel Barrejón , Pablo M. Olmos , Antonio Artés-Rodríguez

User attributes, such as gender and education, face severe incompleteness in social networks. In order to make this kind of valuable data usable for downstream tasks like user profiling and personalized recommendation, attribute inference…

Machine Learning · Computer Science 2021-06-01 Yadong Zhou , Zhihao Ding , Xiaoming Liu , Chao Shen , Lingling Tong , Xiaohong Guan

Missing data is a common challenge in biomedical research. This fact, along with growing dataset volumes of the modern era, make the issue of computationally-efficient analysis with missing data of crucial practical importance. A general…

Methodology · Statistics 2022-04-22 Giorgos Bakoyannis , Philani B. Mpofu , Andrea Broyles , Brian B. Dixon

In the field of machine learning, it is still a critical issue to identify and supervise the learned representation without manually intervening or intuition assistance to extract useful knowledge or serve for the downstream tasks. In this…

Machine Learning · Computer Science 2025-12-10 Shiqi Liu , Jingxin Liu , Qian Zhao , Xiangyong Cao , Huibin Li , Deyu Meng , Hongying Meng , Sheng Liu

In recent years, Artificial Neural Networks (ANNs) have been introduced in Structural Health Monitoring (SHM) systems. A semi-supervised method with a data-driven approach allows the ANN training on data acquired from an undamaged…

Machine Learning · Computer Science 2023-08-15 Andrea Pollastro , Giusiana Testa , Antonio Bilotta , Roberto Prevete

Dynamical variational autoencoders (DVAEs) are a class of deep generative models with latent variables, dedicated to model time series of high-dimensional data. DVAEs can be considered as extensions of the variational autoencoder (VAE) that…

Sound · Computer Science 2022-10-04 Xiaoyu Bie , Simon Leglaive , Xavier Alameda-Pineda , Laurent Girin

Missing data is a ubiquitous challenge in data analysis, often leading to biased and inaccurate results. Traditional imputation methods usually assume that the missingness mechanism is missing-at-random (MAR), where the missingness is…

Methodology · Statistics 2026-03-30 Huiming Xie , Fei Xue , Xiao Wang

Anomaly detection using dimensionality reduction has been an essential technique for monitoring multidimensional data. Although deep learning-based methods have been well studied for their remarkable detection performance, their…

Machine Learning · Statistics 2018-12-24 Yasuhiro Ikeda , Kengo Tajiri , Yuusuke Nakano , Keishiro Watanabe , Keisuke Ishibashi

A key advance in learning generative models is the use of amortized inference distributions that are jointly trained with the models. We find that existing training objectives for variational autoencoders can lead to inaccurate amortized…

Machine Learning · Computer Science 2018-05-31 Shengjia Zhao , Jiaming Song , Stefano Ermon

Self-supervised learning has attracted increasing attention as it learns data-driven representation from data without annotations. Vision transformer-based autoencoder (ViT-AE) by He et al. (2021) is a recent self-supervised learning…

Computer Vision and Pattern Recognition · Computer Science 2023-05-17 Chinmay Prabhakar , Hongwei Bran Li , Jiancheng Yang , Suprosana Shit , Benedikt Wiestler , Bjoern Menze

Variational autoencoders (VAEs) are powerful deep generative models widely used to represent high-dimensional complex data through a low-dimensional latent space learned in an unsupervised manner. In the original VAE model, the input data…

Machine Learning · Computer Science 2022-07-05 Laurent Girin , Simon Leglaive , Xiaoyu Bie , Julien Diard , Thomas Hueber , Xavier Alameda-Pineda

The variational autoencoder (VAE) is a popular combination of deep latent variable model and accompanying variational learning technique. By using a neural inference network to approximate the model's posterior on latent variables, VAEs…

Machine Learning · Computer Science 2019-01-30 Junxian He , Daniel Spokoyny , Graham Neubig , Taylor Berg-Kirkpatrick

Deep learning (DL) algorithms can be used to automate paranasal anomaly detection from Magnetic Resonance Imaging (MRI). However, previous works relied on supervised learning techniques to distinguish between normal and abnormal samples.…

Semi-supervised learning is sought for leveraging the unlabelled data when labelled data is difficult or expensive to acquire. Deep generative models (e.g., Variational Autoencoder (VAE)) and semisupervised Generative Adversarial Networks…

Machine Learning · Computer Science 2019-05-09 Xiang Zhang , Lina Yao , Feng Yuan

Due to their unsupervised training and uncertainty estimation, deep Variational Autoencoders (VAEs) have become powerful tools for reconstruction-based Time Series Anomaly Detection (TSAD). Existing VAE-based TSAD methods, either…

Machine Learning · Computer Science 2024-01-09 Zhangkai Wu , Longbing Cao , Qi Zhang , Junxian Zhou , Hui Chen

As the adoption of Artificial Intelligence (AI) models expands into critical real-world applications, ensuring the explainability of these models becomes paramount, particularly in sensitive fields such as medicine and finance. Linear…

Machine Learning · Computer Science 2024-10-10 Tuan L. Vo , Uyen Dang , Thu Nguyen
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