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Raman Spectroscopy offers an in-situ, rapid, and non-destructive characterization tool for chemical analysis of diverse samples with no or minimal preparation. However, due to the inherent weak signal of conventional Raman spectroscopy,…

Gold nanoparticles (AuNPs) have been shown to possess properties beneficial for the treatment of cancerous tumors by acting as radiosensitizers for both photon and ion radiation. Blood circulation time is usually increased by coating the…

Atomic and Molecular Clusters · Physics 2016-09-21 Kaspar Haume , Nigel J. Mason , Andrey Solov'yov

In radiobiological experiments, the cells can either float in suspension or adhere to the walls of the sample holder. When irradiation is performed in the presence of dose modifying agents such as gold nanoparticles (AuNPs), the different…

Medical Physics · Physics 2025-12-04 Hans Rabus , Oswald Msosa Mkanda

Gold nanoparticles have been conceived as a radiosensitizer in cancer radiation therapy, but one of the important questions for primary drug screening is what size of gold nanoparticles can optimally enhance radiation effects. Herein, we…

Medical Physics · Physics 2012-10-03 Xiao-Dong Zhang , Di Wu , Xiu Shen , Jie Chen , Yuan-Ming Sun , Pei-Xun Liu , Xing-Jie Liang

We report on the high-pressure optical and mechanical properties of penta-twinned gold nanoparticles (PT-AuNPs) of different geometries: decahedra, rods and bipyramids. Our results show that, unlike single-crystal (SC-AuNPs), PT-AuNPs…

When irradiation is performed with gold nanoparticles (AuNPs), a different shape of cells in suspension or adherent to walls may result in different probability of cell survival. In a recent study, differences of up to a factor of 2 were…

Medical Physics · Physics 2025-12-04 Hans Rabus , Oswald Msosa Mkanda

In this work the synthesis and characterization of novel gold-nanodiamond nanoparticles was performed. The synthesis was based on the reduction of gold onto the different types of nanodiamond (annealed or annealed and oxidized, 50 or 230…

We systematically investigated and quantified how gold (Au) metal nanoparticles (NPs) optical spectra change upon introduction into biological tissue phantoms environment, in which the AuNPs can agglomerate. Quantitative knowledge of how…

Applied Physics · Physics 2021-03-17 J. C. R. Araujo , A. F. G. Monte , R. L. Serrano , W. Iwamoto , A. Antunes , O. Brener , M. Foschini

Gold nanoparticles (AuNPs) play an important role in fundamental research and development due to their versatile applications and biocompatibility. This study addresses the aging of three AuNP suspensions after the addition of various…

Soft Condensed Matter · Physics 2025-02-04 Philipp Ritzert , Alexandra Striegel , Regine von Klitzing

Gold nanoparticles (GNPs) constitute a breakthrough in modern chemistry. The recent success in the synthesis and total structure determination of the precise-composition GNPs provides exciting opportunities for fundamental studies and…

Materials Science · Physics 2015-02-05 Vitaly Chaban

A new type of metabolizable and efficient radiosensitizer for cancer radiotherapy is presented in this study by combining ultrasmall Au nanoclusters (NCs, <2 nm) with biocompatible coating ligands (glutathione, GSH). The new nano-construct…

Purpose: Pulsed-laser irradiation of light-absorbing gold nanoparticles (AuNPs) attached to cells transiently increases cell membrane permeability for targeted molecule delivery. Here, we targeted EGFR on the ovarian carcinoma cell line…

Biomolecules · Quantitative Biology 2018-10-09 Cuiping Yao , Florian Rudnitzki , Gereon Huettmann , Zhenxi Zhang , Ramtin Rahmanzadeh

Precise radiation delivery is critical for effective radiotherapy, and gold nanoparticles (AuNPs) have emerged as promising tools to enhance local dose deposition while sparing the surrounding healthy tissue. In this study, the PENELOPE…

Radiotherapy is often the most straightforward first line cancer treatment for solid tumors. While it is highly effective against tumors, there is also collateral damage to healthy proximal tissues especially with high doses. The use of…

Turning gold nanoparticles (AuNPs) into nanoscale heat sources via light irradiation has prompted significant research interest, particularly for biomedical applications over the past few decades. The AuNP's tunable photothermal effect,…

Hypothesis: Introducing charged terminal groups to polymers that graft nanoparticles enables Coulombic control over their assembly by tuning the pH and salinity of aqueous suspensions. Experiments: Gold nanoparticles (AuNPs) are grafted…

Mesoscale and Nanoscale Physics · Physics 2023-12-08 Hyeong Jin Kim , Binay P. Nayak , Honghu Zhang , Benjamin M. Ocko , Alex Travesset , David Vaknin , Surya K. Mallapragada , Wenjie Wang

In this paper, we derive a variance-driven Local-Effect-Model ($\sigma$-LEM) to predict radiosensitization due to gold nanoparticles (AuNP). Assuming that the number of Au photo-ionisations scales strictly with particle volume…

Medical Physics · Physics 2025-07-17 Pedro Teles

In their article published in Phys. Med. Biol. 60 (2015) 4149-4168, Lin et al studied the radiosensitizing effect of gold nanoparticles (GNPs) using radiation transport simulations and a biological model for the survival of irradiated…

Medical Physics · Physics 2023-02-13 Hans Rabus

This study investigates the dynamic control of third-order nonlinear optical absorption properties of gold nanoparticles (AuNPs) dispersed in nematic liquid crystals (LC). By leveraging the reconfigurable nature of liquid crystals under…

Soft Condensed Matter · Physics 2025-02-17 Shengwei Wang , Mohamed Amine Gharbi , Chandra S Yelleswarapu

Global geometry optimization and time-dependent density functional theory calculations have been used to study the structural evolution and optical properties of (AgAu)n (n=2-6) nanoalloys both as individual clusters and as clusters…

Materials Science · Physics 2017-02-23 Dennis Palagin , Jonathan P. K. Doye
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