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The paper presents the application of Variational Autoencoders (VAE) for data dimensionality reduction and explorative analysis of mass spectrometry imaging data (MSI). The results confirm that VAEs are capable of detecting the patterns…

Quantitative Methods · Quantitative Biology 2017-08-25 Paolo Inglese , James L. Alexander , Anna Mroz , Zoltan Takats , Robert Glen

In this tutorial, we explore Variational Autoencoders (VAEs), an essential framework for unsupervised learning, particularly suited for high-dimensional datasets such as neuroimaging. By integrating deep learning with Bayesian inference,…

Image and Video Processing · Electrical Eng. & Systems 2025-01-15 C. Vázquez-García , F. J. Martínez-Murcia , F. Segovia Román , Juan M. Górriz Sáez

Variation Autoencoder (VAE) has become a powerful tool in modeling the non-linear generative process of data from a low-dimensional latent space. Recently, several studies have proposed to use VAE for unsupervised clustering by using…

Machine Learning · Computer Science 2021-06-29 Qingyu Zhao , Nicolas Honnorat , Ehsan Adeli , Kilian M. Pohl

Separating shared and independent features is crucial for multi-phase contrast-enhanced (CE) MRI synthesis. However, existing methods use deep autoencoder generators with low parameter efficiency and lack interpretable training strategies.…

Computer Vision and Pattern Recognition · Computer Science 2025-10-06 Xiaoyan Kui , Qianmu Xiao , Qqinsong Li , Zexin Ji , JIelin Zhang , Beiji Zou

We propose an unsupervised learning methodology with descriptors based on Topological Data Analysis (TDA) concepts to describe the local structural properties of materials at the atomic scale. Based only on atomic positions and without a…

Disordered Systems and Neural Networks · Physics 2022-04-20 Sébastien Becker , Emilie Devijver , Rémi Molinier , Noël Jakse

Inverse problems often involve matching observational data using a physical model that takes a large number of parameters as input. These problems tend to be under-constrained and require regularization to impose additional structure on the…

Computational Physics · Physics 2019-06-07 Daniel O'Malley , John K. Golden , Velimir V. Vesselinov

Although unsupervised generative modeling of an image dataset using a Variational AutoEncoder (VAE) has been used to detect anomalous images, or anomalous regions in images, recent works have shown that this method often identifies images…

Computer Vision and Pattern Recognition · Computer Science 2020-08-13 David Dehaene , Pierre Eline

We demonstrate the application of machine learning for rapid and accurate extraction of plasmonic particles cluster geometries from hyperspectral image data via a dual variational autoencoder (dual-VAE). In this approach, the information is…

Disordered Systems and Neural Networks · Physics 2022-08-09 Muammer Y. Yaman , Sergei V. Kalinin , Kathryn N. Guye , David Ginger , Maxim Ziatdinov

We propose Tree Variational Autoencoder (TreeVAE), a new generative hierarchical clustering model that learns a flexible tree-based posterior distribution over latent variables. TreeVAE hierarchically divides samples according to their…

Machine Learning · Computer Science 2023-11-20 Laura Manduchi , Moritz Vandenhirtz , Alain Ryser , Julia Vogt

Zero-shot skeleton-based action recognition aims to develop models capable of identifying actions beyond the categories encountered during training. Previous approaches have primarily focused on aligning visual and semantic representations…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Wenhan Wu , Zhishuai Guo , Chen Chen , Hongfei Xue , Aidong Lu

Learning compact and interpretable representations of data is a critical challenge in scientific image analysis. Here, we introduce Affinity-VAE, a generative model that enables us to impose our scientific intuition about the similarity of…

Variational Autoencoders (VAE) are widely used for dimensionality reduction of large-scale tabular and image datasets, under the assumption of independence between data observations. In practice, however, datasets are often correlated, with…

Machine Learning · Statistics 2024-12-25 Giora Simchoni , Saharon Rosset

The ability to extract generative parameters from high-dimensional fields of data in an unsupervised manner is a highly desirable yet unrealized goal in computational physics. This work explores the use of variational autoencoders (VAEs)…

Computational Physics · Physics 2021-11-16 Christian Jacobsen , Karthik Duraisamy

While unsupervised variational autoencoders (VAE) have become a powerful tool in neuroimage analysis, their application to supervised learning is under-explored. We aim to close this gap by proposing a unified probabilistic model for…

Machine Learning · Computer Science 2019-07-15 Qingyu Zhao , Ehsan Adeli , Nicolas Honnorat , Tuo Leng , Kilian M. Pohl

Sensor fusion can significantly improve the performance of many computer vision tasks. However, traditional fusion approaches are either not data-driven and cannot exploit prior knowledge nor find regularities in a given dataset or they are…

Computer Vision and Pattern Recognition · Computer Science 2022-09-26 Fabian Duffhauss , Ngo Anh Vien , Hanna Ziesche , Gerhard Neumann

We propose to learn model invariances as a means of interpreting a model. This is motivated by a reverse engineering principle. If we understand a problem, we may introduce inductive biases in our model in the form of invariances.…

Machine Learning · Computer Science 2020-07-16 An-phi Nguyen , María Rodríguez Martínez

We present the development of a semi-supervised regression method using variational autoencoders (VAE), which is customized for use in soft sensing applications. We motivate the use of semi-supervised learning considering the fact that…

Machine Learning · Computer Science 2022-12-12 Yilin Zhuang , Zhuobin Zhou , Burak Alakent , Mehmet Mercangöz

Data-driven fault diagnostics of safety-critical systems often faces the challenge of a complete lack of labeled data associated with faulty system conditions (i.e., fault types) at training time. Since an unknown number and nature of fault…

Machine Learning · Computer Science 2020-10-01 Manuel Arias Chao , Bryan T. Adey , Olga Fink

We propose a variational autoencoder (VAE) approach for parameter estimation in nonlinear mixed-effects models based on ordinary differential equations (NLME-ODEs) using longitudinal data from multiple subjects. In moderate dimensions,…

Methodology · Statistics 2026-02-11 Zhe Li , Mélanie Prague , Rodolphe Thiébaut , Quentin Clairon

In recent years Variation Autoencoders have become one of the most popular unsupervised learning of complicated distributions.Variational Autoencoder (VAE) provides more efficient reconstructive performance over a traditional autoencoder.…

Machine Learning · Statistics 2017-07-12 Gautam Ramachandra