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We study an infection-age structured epidemic model in which both the infectivity and the rate of loss of immunity depend on the time-since-infection. The model can be equivalently viewed as a nonlinear renewal equation for the incidence of…

Dynamical Systems · Mathematics 2025-11-13 Francesca Scarabel , Harry Coldwell , Tyler Cassidy

Human mobility and activity patterns mediate contagion on many levels, including the spatial spread of infectious diseases, diffusion of rumors, and emergence of consensus. These patterns however are often dominated by specific locations…

Physics and Society · Physics 2011-07-05 Duygu Balcan , Alessandro Vespignani

Most of the common used models of epidemic spreading allow contaminating many neighbors of a particular node in the network. They are usually analyzed by differential equations on probability vectors. We propose a model of epidemic…

Physics and Society · Physics 2018-02-14 Wojciech Ganczarek

Deterministic compartmental models have been used extensively in modeling epidemic propagation. These models are required to fit available data and numerical procedures are often implemented to this end. But not every model architecture is…

Populations and Evolution · Quantitative Biology 2021-11-23 Gabriel Turinici

Current modeling of infectious diseases allows for the study of complex and realistic scenarios that go from the population to the individual level of description. However, most epidemic models assume that the spreading process takes place…

Physics and Society · Physics 2015-04-15 Joaquín Sanz , Cheng-Yi Xia , Sandro Meloni , Yamir Moreno

We study contact epidemic models for the spread of infective diseases in finite populations. The size dependence enters in the infection rate. The dynamics of such models is then analyzed within the deterministic approximation, as well as…

Populations and Evolution · Quantitative Biology 2020-04-07 Ph. Blanchard , S. Nicolis

The duration, type and structure of connections between individuals in real-world populations play a crucial role in how diseases invade and spread. Here, we incorporate the aforementioned heterogeneities into a model by considering a…

Physics and Society · Physics 2018-04-05 Rosanna C Barnard , Istvan Z Kiss , Luc Berthouze , Joel C Miller

The aim of this paper is to present an, admittedly somewhat subjective, bird's eye view of the mathematical theory concerning the spread of an infectious disease in a susceptible host population with static structure, culminating in a…

Populations and Evolution · Quantitative Biology 2025-08-06 Odo Diekmann , Hisashi Inaba , Horst R. Thieme

The current work deals with an epidemic model on the complete graph K_n on n vertices in a non-homogeneous setting, where the vertices may have distinct types. Different types differ in the probability of getting infected, and/or in the…

Probability · Mathematics 2022-05-10 Daniela Bertacchi , Jürgen Kampf , Ecaterina Sava-Huss , Fabio Zucca

Approximating the time to extinction of infection is an important problem in infection modelling. A variety of different approaches have been proposed in the literature. We study the performance of a number of such methods, and characterize…

Probability · Mathematics 2017-07-11 Damian Clancy , Elliott Tjia

A common theme among the proposed models for network epidemics is the assumption that the propagating object, i.e., a virus or a piece of information, is transferred across the nodes without going through any modification or evolution.…

Physics and Society · Physics 2019-11-05 Rashad Eletreby , Yong Zhuang , Kathleen M. Carley , Osman Yağan , H. Vincent Poor

We study the spreading of an infection within an SIS epidemiological model on a network. Susceptible agents are given the opportunity of breaking their links with infected agents. Broken links are either permanently removed or reconnected…

Populations and Evolution · Quantitative Biology 2007-11-07 Damian H. Zanette , Sebastian Risau Gusman

Transmission models for infectious diseases are typically formulated in terms of dynamics between individuals or groups with processes such as disease progression or recovery for each individual captured phenomenologically, without…

Infectious disease dynamics operate across multiple biological scales, with within-host viral dynamics being a key driver of between-host transmission. However, while models that explicitly link these scales exist, none have been developed…

Applications · Statistics 2026-04-23 Dylan J. Morris , Lauren Kennedy , Andrew J. Black

We study the Susceptible-Infected-Susceptible model of the spread of an endemic infection. We calculate an exact expression for the mean number of transmissions for all values of the population and the infectivity. We derive the large-N…

Populations and Evolution · Quantitative Biology 2007-09-20 David A. Kessler

This paper addresses the question of how population diffusion affects the formation of the spatial patterns in the spatial epidemic model by Turing mechanisms. In particular, we present theoretical analysis to results of the numerical…

Populations and Evolution · Quantitative Biology 2009-09-29 Quan-Xing Liu , Zhen Jin

We develop a stochastic framework for viral population dynamics at the cellular level that explicitly incorporates the replication cycle with random stage durations. The model is formulated as a structured birth-death process coupled with a…

Populations and Evolution · Quantitative Biology 2026-05-13 Seong Jun Park

The appearance of the coronavirus (COVID-19) in late 2019 has dominated the news in the last few months as it developed into a pandemic. In many mathematics and physics classrooms, instructors are using the time series of the number of…

Physics Education · Physics 2020-07-24 Paulo H. Acioli

We present a theory for the laboratory and epidemiological data for incubation times in infectious prion diseases. The central feature of our model is that slow growth of misfolded protein-aggregates from small initial seeds controls the…

Condensed Matter · Physics 2016-08-16 R. V. Kulkarni , A. Slepoy , R. R. P. Singh , D. L. Cox , D. Mobley , F. Pázmándi

In this paper we consider a model based on branching process theory for the proliferation and the dissemination network of T cells in the adaptive immune response. A multi-type Galton Watson branching process is assumed as the basic…

Quantitative Methods · Quantitative Biology 2015-06-09 Alessandro Boianelli , Antonio Vicino