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Cardiac auscultation is an essential clinical skill, requiring excellent hearing to distinguish subtle differences in timing and pitch of heart sounds. However, diagnosing solely from these sounds is often challenging due to interference…

12-lead ECGs with high sampling frequency are the clinical gold standard for arrhythmia detection, but their short-term, spot-check nature often misses intermittent events. Wearable ECGs enable long-term monitoring but suffer from…

Machine Learning · Computer Science 2025-11-24 Angelina Yan , Matt L. Sampson , Peter Melchior

We propose the Nonlinear Regression Convolutional Encoder-Decoder (NRCED), a novel framework for mapping a multivariate input to a multivariate output. In particular, we implement our algorithm within the scope of 12-lead surface…

Signal Processing · Electrical Eng. & Systems 2020-12-14 Anton Banta , Romain Cosentino , Mathews M John , Allison Post , Skyler Buchan , Mehdi Razavi , Behnaam Aazhang

The interpretation of chest radiographs is an essential task for the detection of thoracic diseases and abnormalities. However, it is a challenging problem with high inter-rater variability and inherent ambiguity due to inconclusive…

Computer Vision and Pattern Recognition · Computer Science 2019-06-20 Florin C. Ghesu , Bogdan Georgescu , Eli Gibson , Sebastian Guendel , Mannudeep K. Kalra , Ramandeep Singh , Subba R. Digumarthy , Sasa Grbic , Dorin Comaniciu

Phonocardiogram (PCG) analysis is vital for cardiovascular disease diagnosis, yet the scarcity of labeled pathological data hinders the capability of AI systems. To bridge this, we introduce H-LDM, a Hierarchical Latent Diffusion Model for…

Machine Learning · Computer Science 2026-02-13 Chenyang Xu , Siming Li , Hao Wang

An assumption-free automatic check of medical images for potentially overseen anomalies would be a valuable assistance for a radiologist. Deep learning and especially Variational Auto-Encoders (VAEs) have shown great potential in the…

Machine Learning · Computer Science 2019-07-12 David Zimmerer , Fabian Isensee , Jens Petersen , Simon Kohl , Klaus Maier-Hein

Classic variational autoencoders are used to learn complex data distributions, that are built on standard function approximators. Especially, VAE has shown promise on a lot of complex task. In this paper, a new autoencoder model -…

Computer Vision and Pattern Recognition · Computer Science 2020-01-13 Qiuyu Zhu , Ruixin Zhang

This study investigates the use of non-linear unsupervised dimensionality reduction techniques to compress a music dataset into a low-dimensional representation which can be used in turn for the synthesis of new sounds. We systematically…

Audio and Speech Processing · Electrical Eng. & Systems 2019-05-27 Fanny Roche , Thomas Hueber , Samuel Limier , Laurent Girin

Cardiovascular diseases are one of the leading cause of death in today's world and early screening of heart condition plays a crucial role in preventing them. The heart sound signal is one of the primary indicator of heart condition and can…

Ensuring timely and accurate diagnosis of medical conditions is paramount for effective patient care. Electrocardiogram (ECG) signals are fundamental for evaluating a patient's cardiac health and are readily available. Despite this, little…

Signal Processing · Electrical Eng. & Systems 2025-11-21 Juan Miguel Lopez Alcaraz , Nils Strodthoff

Electrocardiogram (ECG) is a simple non-invasive measure to identify heart-related issues such as irregular heartbeats known as arrhythmias. While artificial intelligence and machine learning is being utilized in a wide range of healthcare…

Machine Learning · Computer Science 2022-07-11 Minh Cao , Tianqi Zhao , Yanxun Li , Wenhao Zhang , Peyman Benharash , Ramin Ramezani

We have carried out a pilot study on a standard collection of electrocardiograms from patients who suffer from congestive heart failure, and subjects without cardiac pathology, using receiver-operating-characteristic (ROC) analysis. The…

chao-dyn · Physics 2007-05-23 Stefan Thurner , Markus C. Feurstein , Malvin C. Teich

Cancer is a heterogeneous disease with diverse molecular etiologies and outcomes. The Cancer Genome Atlas (TCGA) has released a large compendium of over 10,000 tumors with RNA-seq gene expression measurements. Gene expression captures the…

Genomics · Quantitative Biology 2017-11-15 Gregory P. Way , Casey S. Greene

Simultaneous electrocardiography (ECG) and phonocardiogram (PCG) provide a comprehensive, multimodal perspective on cardiac function by capturing the heart's electrical and mechanical activities, respectively. However, the distinct and…

Machine Learning · Computer Science 2025-06-13 Sajjad Karimi , Amit J. Shah , Gari D. Clifford , Reza Sameni

The vast majority of cardiovascular diseases may be preventable if early signs and risk factors are detected. Cardiovascular monitoring with body-worn sensor devices like sensor patches allows for the detection of such signs while…

We present a coupled Variational Auto-Encoder (VAE) method that improves the accuracy and robustness of the probabilistic inferences on represented data. The new method models the dependency between input feature vectors (images) and weighs…

Machine Learning · Computer Science 2025-11-25 Shichen Cao , Jingjing Li , Kenric P. Nelson , Mark A. Kon

Electrocardiogram (ECG) is a widely used tool for assessing cardiac function due to its low cost and accessibility. Emergent research shows that ECGs can help make predictions on key outcomes traditionally derived from more complex…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Yuan Gao , Sangwook Kim , Chris McIntosh

This paper proposes a low-cost and highly accurate ECG-monitoring system intended for personalized early arrhythmia detection for wearable mobile sensors. Earlier supervised approaches for personalized ECG monitoring require both abnormal…

Machine Learning · Computer Science 2024-08-23 Mehmet Yamaç , Mert Duman , İlke Adalıoğlu , Serkan Kiranyaz , Moncef Gabbouj

With tens of thousands of electrocardiogram (ECG) records processed by mobile cardiac event recorders every day, heart rhythm classification algorithms are an important tool for the continuous monitoring of patients at risk. We utilise an…

Machine Learning · Computer Science 2020-12-14 Patrick Schwab , Gaetano Scebba , Jia Zhang , Marco Delai , Walter Karlen