Related papers: VoxelHop: Successive Subspace Learning for ALS Dis…

Amyotrophic Lateral Sclerosis (ALS) is a complex neurodegenerative disorder involving motor neuron degeneration. Significant research has begun to establish brain magnetic resonance imaging (MRI) as a potential biomarker to diagnose and…

Deep learning has become an important tool for Alzheimer's disease (AD) classification from structural MRI. Many existing studies analyze individual 2D slices extracted from MRI volumes, while clinical neuroimaging practice typically relies…

A new machine learning methodology, called successive subspace learning (SSL), is introduced in this work. SSL contains four key ingredients: 1) successive near-to-far neighborhood expansion; 2) unsupervised dimension reduction via subspace…

Cardiac cine magnetic resonance imaging (MRI) has been used to characterize cardiovascular diseases (CVD), often providing a noninvasive phenotyping tool.~While recently flourished deep learning based approaches using cine MRI yield…

Amyotrophic Lateral Sclerosis (ALS) constitutes a progressive neurodegenerative disease with varying symptoms, including decline in speech intelligibility. Existing studies, which recognize dysarthria in ALS patients by predicting the…

The successive subspace learning (SSL) principle was developed and used to design an interpretable learning model, known as the PixelHop method,for image classification in our prior work. Here, we propose an improved PixelHop method and…

Amyotrophic Lateral Sclerosis (ALS) is characterized as a rapidly progressive neurodegenerative disease that presents individuals with limited treatment options in the realm of medical interventions and therapies. The disease showcases a…

Texture analysis is a well-known research topic in computer vision and image processing and has many applications. Gradient-based texture methods have become popular in classification problems. For the first time we extend a well-known…

Autism spectrum disorder (ASD) is a complex neurodevelopmental syndrome. Early diagnosis and precise treatment are essential for ASD patients. Although researchers have built many analytical models, there has been limited progress in…

An image anomaly localization method based on the successive subspace learning (SSL) framework, called AnomalyHop, is proposed in this work. AnomalyHop consists of three modules: 1) feature extraction via successive subspace learning (SSL),…

Purpose: Multiple sclerosis (MS) diagnosis requires accurate assessment of white matter hyperintensities (WMH) and ventricular changes on brain MRI. Current methods treat these structures independently, struggle to differentiate normal from…

Deep learning models have shown strong performance in classifying Alzheimer's disease (AD) from R2* maps, but their decision-making remains opaque, raising concerns about interpretability. Previous studies suggest biases in model decisions,…

The exact shape of intracranial aneurysms is critical in medical diagnosis and surgical planning. While voxel-based deep learning frameworks have been proposed for this segmentation task, their performance remains limited. In this study, we…

The ability to predict the future trajectory of a patient is a key step toward the development of therapeutics for complex diseases such as Alzheimer's disease (AD). However, most machine learning approaches developed for prediction of…

Deep learning has shown remarkable success in medical image analysis, but its reliance on large volumes of high-quality labeled data limits its applicability. While noisy labeled data are easier to obtain, directly incorporating them into…

Diagnosing Autism Spectrum Disorder (ASD) is a challenging problem, and is based purely on behavioral descriptions of symptomology (DSM-5/ICD-10), and requires informants to observe children with disorder across different settings (e.g.…

Super-resolution ultrasound imaging (SRUS) is an active area of research as it brings up to a ten-fold improvement in the resolution of microvascular structures. The limitations to the clinical adoption of SRUS include long acquisition…

The majority of current research in deep learning based image registration addresses inter-patient brain registration with moderate deformation magnitudes. The recent Learn2Reg medical registration benchmark has demonstrated that…

This study introduces a deep learning framework for the inferential exploration of latent representations in 3D brain MRI, leveraging a simple convolutional autoencoder with a hierarchical encoder and a compact latent space. Trained on…

Convolutional Neural Networks (CNNs) have proven to be state-of-the-art models for supervised computer vision tasks, such as image classification. However, large labeled data sets are generally needed for the training and validation of such…