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The main objective of this paper is to solve the optimization problem that is associated with the classification of DNA samples in PCR plates for Sanger sequencing. To achieve this goal, we design an integer linear programming model. Given…

Data Structures and Algorithms · Computer Science 2024-01-23 Luisa Carpente , Ana Cerdeira-Pena , Silvia Lorenzo-Freire , Ángeles S. Places

Over the past years, the ever-growing trend on data storage demand, more specifically for "cold" data (rarely accessed data), has motivated research for alternative systems of data storage. Because of its biochemical characteristics,…

Machine Learning · Computer Science 2022-03-21 Xavier Pic , Marc Antonini

Convolutional Neural Networks (CNNs) continue to achieve great success in classification tasks as innovative techniques and complex multi-path architecture topologies are introduced. Neural Architecture Search (NAS) aims to automate the…

Neural and Evolutionary Computing · Computer Science 2023-12-14 Trevor Londt , Xiaoying Gao , Peter Andreae , Yi Mei

DNA sequencing allows for the determination of the genetic code of an organism, and therefore is an indispensable tool that has applications in Medicine, Life Sciences, Evolutionary Biology, Food Sciences and Technology, and Agriculture. In…

Quantum Physics · Physics 2023-04-24 Nouhaila Innan , Muhammad Al-Zafar Khan

Over the past several years, DNA sequencing has emerged as one of the driving forces in life-sciences, paving the way for affordable and accurate whole genome sequencing. As genomes represent the entirety of an organism's hereditary…

Cryptography and Security · Computer Science 2015-02-17 Emiliano De Cristofaro

Genome modeling conventionally treats gene sequence as a language, reflecting its structured motifs and long-range dependencies analogous to linguistic units and organization principles such as words and syntax. Recent studies utilize…

Machine Learning · Computer Science 2025-05-06 Lei Mao , Yuanhe Tian , Yan Song

This paper considers a convolutional neural network transformation that reduces computation complexity and thus speedups neural network processing. Usage of convolutional neural networks (CNN) is the standard approach to image recognition…

Computer Vision and Pattern Recognition · Computer Science 2020-02-19 Elena Limonova , Alexander Sheshkus , Dmitry Nikolaev

Neural Architecture Search (NAS) has emerged as a powerful approach for automating neural network design. However, existing NAS methods face critical limitations in real-world deployments: architectures lack adaptability across scenarios,…

Machine Learning · Computer Science 2025-08-29 Maolin Wang , Tianshuo Wei , Sheng Zhang , Ruocheng Guo , Wanyu Wang , Shanshan Ye , Lixin Zou , Xuetao Wei , Xiangyu Zhao

DNA exhibits remarkable potential as a data storage solution due to its impressive storage density and long-term stability, stemming from its inherent biomolecular structure. However, developing this novel medium comes with its own set of…

Image and Video Processing · Electrical Eng. & Systems 2023-09-14 Trung Hieu Le , Xavier Pic , Jeremy Mateos , Marc Antonini

In [1], the authors proposed a new model of DNA storage system that integrates all three steps of retrieval and introduced the concept of DNA-correcting codes, which guarantees that the output of the storage system can be decoded to the…

Information Theory · Computer Science 2023-11-17 Huawei Wu

The process of DNA-based data storage (DNA storage for short) can be mathematically modelled as a communication channel, termed DNA storage channel, whose inputs and outputs are sets of unordered sequences. To design error correcting codes…

Information Theory · Computer Science 2020-06-11 Wentu Song , Kui Cai , Kees A. Schouhamer Immink

Nowadays, Cellular Neural Networks (CNN) are practically implemented in parallel, analog computers, showing a fast developing trend. Physicist must be aware that such computers are appropriate for solving in an elegant manner practically…

Disordered Systems and Neural Networks · Physics 2016-02-17 Mária Ercsey-Ravasz , Tamás Roska , Zoltán Néda

Machine learning can precisely identify different cancer tumors at any stage by classifying cancerous and healthy samples based on their genomic profile. We have developed novel methods of MLAC (Machine Learning Against Cancer) achieving…

Genomics · Quantitative Biology 2020-09-15 Arash Hooshmand

With ongoing developments and innovations in single-cell RNA sequencing methods, advancements in sequencing performance could empower significant discoveries as well as new emerging possibilities to address biological and medical…

Applications · Statistics 2019-12-19 Jiawei Long , Yu Xia

Engineering the entire genome of an organism enables large-scale changes in organization, function, and external interactions, with significant implications for industry, medicine, and the environment. Improvements to DNA synthesis and…

Genomics · Quantitative Biology 2020-03-25 Bryan A. Bartley , Jacob Beal , Jonathan R. Karr , Elizabeth A. Strychalski

In hardware-aware Differentiable Neural Architecture Search (DNAS), it is challenging to compute gradients of hardware metrics to perform architecture search. Existing works rely on linear approximations with limited support to customized…

Machine Learning · Computer Science 2021-11-25 Qian Jiang , Xiaofan Zhang , Deming Chen , Minh N. Do , Raymond A. Yeh

Neural architecture search (NAS) typically consists of three main steps: training a super-network, training and evaluating sampled deep neural networks (DNNs), and training the discovered DNN. Most of the existing efforts speed up some…

Computer Vision and Pattern Recognition · Computer Science 2021-04-02 Tien-Ju Yang , Yi-Lun Liao , Vivienne Sze

In the past few years, Differentiable Neural Architecture Search (DNAS) rapidly imposed itself as the trending approach to automate the discovery of deep neural network architectures. This rise is mainly due to the popularity of DARTS, one…

Machine Learning · Computer Science 2023-05-02 Alexandre Heuillet , Ahmad Nasser , Hichem Arioui , Hedi Tabia

Efficient processing of large-scale time series data is an intricate problem in machine learning. Conventional sensor signal processing pipelines with hand engineered feature extraction often involve huge computational cost with high…

This paper introduces a new solution to DNA storage that integrates all three steps of retrieval, namely clustering, reconstruction, and error correction. DNA-correcting codes are presented as a unique solution to the problem of ensuring…

Information Theory · Computer Science 2024-07-02 Avital Boruchovsky , Daniella Bar-Lev , Eitan Yaakobi