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Metamaterials, known for their ability to manipulate light at subwavelength scales, face significant design challenges due to their complex and sophisticated structures. Consequently, deep learning has emerged as a powerful tool to…

Optics · Physics 2025-11-21 Shujie Yang , Xuzhe Zhao , Yuqi Zhang , Yansong Tang , Kaichen Dong

Computer-assisted synthesis planning aims to help chemists find better reaction pathways faster. Finding viable and short pathways from sugar molecules to value-added chemicals can be modeled as a retrosynthesis planning problem with a…

Other Computer Science · Computer Science 2019-11-19 Peihong Jiang , Hieu Doan , Sandeep Madireddy , Rajeev Surendran Assary , Prasanna Balaprakash

The advent of computational statistical disciplines, such as machine learning, is leading to a paradigm shift in the way we conceive the design of new compounds. Today computational science does not only provide a sound understanding of…

Materials Science · Physics 2019-11-07 Alessandro Lunghi , Stefano Sanvito

Designing microwave absorbers with customized spectrums is an attractive topic in both scientific and engineering communities. However, due to the massive number of design parameters involved, the design process is typically time-consuming…

Applied Physics · Physics 2023-11-27 Xiangxu He , Xiaohan Cui , C. T. Chan

The feed-forward architectures of recently proposed deep super-resolution networks learn representations of low-resolution inputs, and the non-linear mapping from those to high-resolution output. However, this approach does not fully…

Computer Vision and Pattern Recognition · Computer Science 2018-03-08 Muhammad Haris , Greg Shakhnarovich , Norimichi Ukita

Retrosynthesis consists of breaking down a chemical compound recursively step-by-step into molecular precursors until a set of commercially available molecules is found with the goal to provide a synthesis route. Its two primary research…

Artificial Intelligence · Computer Science 2024-03-12 Paula Torren-Peraire , Alan Kai Hassen , Samuel Genheden , Jonas Verhoeven , Djork-Arne Clevert , Mike Preuss , Igor Tetko

Inline holographic imaging presents an ill-posed inverse problem of reconstructing objects' complex amplitude from recorded diffraction patterns. Although recent deep learning approaches have shown promise over classical phase retrieval…

Optics · Physics 2025-07-02 Chanseok Lee , Fakhriyya Mammadova , Jiseong Barg , Mooseok Jang

The study of structure-spectrum relationships is essential for spectral interpretation, impacting structural elucidation and material design. Predicting spectra from molecular structures is challenging due to their complex relationships.…

Computational Physics · Physics 2024-08-29 Fanjie Xu , Wentao Guo , Feng Wang , Lin Yao , Hongshuai Wang , Fujie Tang , Zhifeng Gao , Linfeng Zhang , Weinan E , Zhong-Qun Tian , Jun Cheng

Ultrasound reflection tomography is widely used to image large complex specimens that are only accessible from a single side, such as well systems and nuclear power plant containment walls. Typical methods for inverting the measurement rely…

Image and Video Processing · Electrical Eng. & Systems 2018-10-01 Hani Almansouri , S. V. Venkatakrishnan , Gregery T. Buzzard , Charles A. Bouman , Hector Santos-Villalobos

Transformer-based large language models have remarkable potential to accelerate design optimization for applications such as drug development and materials discovery. Self-supervised pretraining of transformer models requires large-scale…

Machine Learning · Computer Science 2023-10-27 Pei Zhang , Logan Kearney , Debsindhu Bhowmik , Zachary Fox , Amit K. Naskar , John Gounley

Medical imaging is an invaluable resource in medicine as it enables to peer inside the human body and provides scientists and physicians with a wealth of information indispensable for understanding, modelling, diagnosis, and treatment of…

Image and Video Processing · Electrical Eng. & Systems 2022-08-25 Hanene Ben Yedder , Ben Cardoen , Ghassan Hamarneh

Predicting whether a chemical structure shares a desired biological effect can have a significant impact for in-silico compound screening in early drug discovery. In this study, we developed a deep learning model where compound structures…

Quantitative Methods · Quantitative Biology 2020-04-03 C. Fotis , N. Meimetis , A. Sardis , L. G. Alexopoulos

MOTIVATION: Proteins fold into complex structures that are crucial for their biological functions. Experimental determination of protein structures is costly and therefore limited to a small fraction of all known proteins. Hence, different…

Biomolecules · Quantitative Biology 2018-04-18 David Menéndez Hurtado , Karolis Uziela , Arne Elofsson

Recent methods for deep metric learning have been focusing on designing different contrastive loss functions between positive and negative pairs of samples so that the learned feature embedding is able to pull positive samples of the same…

Computer Vision and Pattern Recognition · Computer Science 2022-11-08 Shichao Kan , Zhiquan He , Yigang Cen , Yang Li , Vladimir Mladenovic , Zhihai He

Deep learning (DL) has revolutionized many fields such as materials design and protein folding. Recent studies have demonstrated the advantages of DL in the inverse design of structural colors, by effectively learning the complex nonlinear…

Optics · Physics 2026-05-22 Sichao Shan , Han Ye , Zhengmei Yang , Junpeng Hou , Zhitong Li

Coarse-grained models are a core computational tool in theoretical chemistry and biophysics. A judicious choice of a coarse-grained model can yield physical insight by isolating the essential degrees of freedom that dictate the…

Statistical Mechanics · Physics 2023-04-12 Shriram Chennakesavalu , David J. Toomer , Grant M. Rotskoff

Computational imaging systems jointly design computation and hardware to retrieve information which is not traditionally accessible with standard imaging systems. Recently, critical aspects such as experimental design and image priors are…

Image and Video Processing · Electrical Eng. & Systems 2020-03-13 Michael Kellman , Jon Tamir , Emrah Boston , Michael Lustig , Laura Waller

Prediction and control of chemical mixing are vital for many scientific areas such as subsurface reactive transport, climate modeling, combustion, epidemiology, and pharmacology. Due to the complex nature of mixing in heterogeneous and…

Machine Learning · Computer Science 2021-12-15 N. V. Jagtap , M. K. Mudunuru , K. B. Nakshatrala

Non-Hermitian systems offer new platforms for unusual physical properties that can be flexibly manipulated by redistribution of the real and imaginary parts of refractive indices, whose presence breaks conventional wave propagation…

Optics · Physics 2022-04-29 W. W. Ahmed , M. Farhat , K. Staliunas , X. Zhang , Y. Wu

We introduce multi-scale energy models to learn the prior distribution of images, which can be used in inverse problems to derive the Maximum A Posteriori (MAP) estimate and to sample from the posterior distribution. Compared to the…

Image and Video Processing · Electrical Eng. & Systems 2024-07-19 Jyothi Rikhab Chand , Mathews Jacob
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