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We study a general setting of neutral evolution in which the population is of finite, constant size and can have spatial structure. Mutation leads to different genetic types ("traits"), which can be discrete or continuous. Under minimal…

Populations and Evolution · Quantitative Biology 2018-11-02 Alex McAvoy , Ben Adlam , Benjamin Allen , Martin A. Nowak

Large-scale multiple testing under static factor models is widely used to detect sparse signals in high-dimensional data. However, static factor models are arguably too stringent because they ignore serial correlation, which seriously…

Statistics Theory · Mathematics 2025-04-04 Xinxin Yang , Lilun Du

Classifiers based on neural networks (NN) often lack a measure of uncertainty in the predicted class. We propose a method to estimate the probability mass function (PMF) of the different classes, as well as the covariance of the estimated…

Machine Learning · Computer Science 2024-10-28 Magnus Malmström , Isaac Skog , Daniel Axehill , Fredrik Gustafsson

Knowing the error distribution is important in many multivariate time series applications. To alleviate the risk of error distribution mis-specification, testing methodologies are needed to detect whether the chosen error distribution is…

Econometrics · Economics 2020-08-04 Donghang Luo , Ke Zhu , Huan Gong , Dong Li

Background: The availability of high throughput methods for measurement of mRNA concentrations makes the reliability of conclusions drawn from the data and global quality control of samples and hybridization important issues. We address…

Quantitative Methods · Quantitative Biology 2007-05-23 S. Bilke , T. Breslin , M. Sigvardsson

The neutron distribution of neutron-rich nuclei provides critical information on the structure of finite nuclei and neutron stars. Parity violating experiments -- such as PREX and CREX -- provide a clean and largely model-independent…

Nuclear Theory · Physics 2021-08-11 Giuliani Pablo , Piekarewicz Jorge

Multisine excitations are widely used for identifying multi-input multi-output systems due to their periodicity, data compression properties, and control over the input spectrum. Despite their popularity, the finite sample statistical…

A substantial fraction of systematic uncertainties in neutrino oscillation experiments stems from the lack of precision in modeling the nucleus when describing the neutrino-nucleus interactions. The Spectral Function (SF) model features a…

High Energy Physics - Phenomenology · Physics 2022-08-29 Jaafar Chakrani , Margherita Buizza Avanzini , Stephen Dolan

Distributed diffusion is a powerful algorithm for multi-task state estimation which enables networked agents to interact with neighbors to process input data and diffuse information across the network. Compared to a centralized approach,…

Multiagent Systems · Computer Science 2020-03-27 Jiani Li , Xenofon Koutsoukos

General genealogical processes such as $\Lambda$- and $\Xi$-coalescents, which respectively model multiple and simultaneous mergers, have important applications in studying marine species, strong positive selection, recurrent selective…

Populations and Evolution · Quantitative Biology 2016-05-10 Jeffrey P. Spence , John A. Kamm , Yun S. Song

In this work, we propose a new inference procedure for understanding non-stationary processes, under the framework of evolutionary spectra developed by Priestley. Among various frameworks of modeling non-stationary processes, the…

Methodology · Statistics 2019-02-20 Yu Xiang , Jie Ding , Vahid Tarokh

A common class of methods for analyzing of multivariate time series, stationary and nonstationary, decomposes the observed series into latent sources. Methods such as principal compoment analysis (PCA), independent component analysis (ICA)…

Methodology · Statistics 2019-12-02 Raanju Ragavendar Sundararajan , Ron D. Frostig , Hernando Ombao

Testing for normality is a widely used procedure in statistics and data analysis, often applied prior to employing methods that rely on the assumption of normally distributed data. While several existing tests target distributional…

Methodology · Statistics 2026-04-07 Akin Anarat , Holger Schwender

The sample frequency spectrum (SFS), which describes the distribution of mutant alleles in a sample of DNA sequences, is a widely used summary statistic in population genetics. The expected SFS has a strong dependence on the historical…

Populations and Evolution · Quantitative Biology 2017-12-19 Zvi Rosen , Anand Bhaskar , Sebastien Roch , Yun S. Song

The reliability of the results of network meta-analysis (NMA) lies in the plausibility of key assumption of transitivity. This assumption implies that the effect modifiers' distribution is similar across treatment comparisons. Transitivity…

It is becoming routine to obtain datasets on DNA sequence variation across several thousands of chromosomes, providing unprecedented opportunity to infer the underlying biological and demographic forces. Such data make it vital to study…

Populations and Evolution · Quantitative Biology 2015-06-24 Paul A. Jenkins , Jonas W. Mueller , Yun S. Song

Constructing generative models for functional observations is an important task in statistical functional analysis. In general, functional data contains both phase (or x or horizontal) and amplitude (or y or vertical) variability. Tradi-…

Computation · Statistics 2019-04-26 J. Derek Tucker , Wei Wu , Anuj Srivastava

In this Review article, a brief description of the stochastic mean-field theory (SMF) for describing reaction dynamics in low-energy heavy-ion collisions at bombarding energies in the vicinity of the Coulomb barrier is presented. In these…

Nuclear Theory · Physics 2025-09-24 S. Ayik , M. Arik , O. Yilmaz , A. S. Umar

In this paper we propose methods for inference of the geometric features of a multivariate density. Our approach uses multiscale tests for the monotonicity of the density at arbitrary points in arbitrary directions. In particular, a…

Statistics Theory · Mathematics 2016-04-18 Konstantin Eckle , Nicolai Bissantz , Holger Dette , Katharina Proksch , Sabrina Einecke

Parameters of the nuclear density functional theory (DFT) models are usually adjusted to experimental data. As a result they carry certain theoretical error, which, as a consequence, carries out to the predicted quantities. In this work we…

Nuclear Theory · Physics 2015-06-22 Markus Kortelainen