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Novel radiotherapy techniques like synchrotron X-ray microbeam radiation therapy (MRT), require fast dose distribution predictions that are accurate at the sub-mm level, especially close to tissue/bone/air interfaces. Monte Carlo physics…

Monocular 3D human pose and shape estimation is an inherently ill-posed problem due to depth ambiguities, occlusions, and truncations. Recent probabilistic approaches learn a distribution over plausible 3D human meshes by maximizing the…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Tom Wehrbein , Marco Rudolph , Bodo Rosenhahn , Bastian Wandt

We evaluated the temporal performance of a deep learning (DL) based artificial intelligence (AI) model for auto segmentation in prostate radiotherapy, seeking to correlate its efficacy with changes in clinical landscapes. Our study involved…

Image and Video Processing · Electrical Eng. & Systems 2023-11-17 Biling Wang , Michael Dohopolski , Ti Bai , Junjie Wu , Raquibul Hannan , Neil Desai , Aurelie Garant , Daniel Yang , Dan Nguyen , Mu-Han Lin , Robert Timmerman , Xinlei Wang , Steve Jiang

Single minibeams of protons, $^{4}$He, $^{12}$C and $^{16}$O in water were modeled with Geant4, and their dose distributions were parameterized with double-Gauss-Rutherford (DGR) functions. Dose distributions from arrays of 16 parallel…

Medical Physics · Physics 2024-12-30 Savva Savenkov , Alexandr Svetlichnyi , Igor Pshenichnov

Renal cell carcinoma represents a significant global health challenge with a low survival rate. This research aimed to devise a comprehensive deep-learning model capable of predicting survival probabilities in patients with renal cell…

Computer Vision and Pattern Recognition · Computer Science 2023-07-10 Maryamalsadat Mahootiha , Hemin Ali Qadir , Jacob Bergsland , Ilangko Balasingham

In recent years, the use of PACS for radiation therapy has become the norm in hospital environment and has suggested for collecting data and management from different TPSs with DICOM objects. However, some TPS does not provide the DVH…

Medical Physics · Physics 2015-03-16 Byung Jun Min , Heerim Nam , Il Sun Jeong , Hyebin Lee

This paper introduces the OPIAID algorithm, a novel approach for predicting and recommending personalized opioid dosages for individual patients. The algorithm optimizes pain management while minimizing opioid related adverse events (ORADE)…

It is not trivial to optimally learn a 3D Convolutional Neural Networks (3D ConvNets) due to high complexity and various options of the training scheme. The most common hand-tuning process starts from learning 3D ConvNets using short video…

Computer Vision and Pattern Recognition · Computer Science 2022-01-12 Zhaofan Qiu , Ting Yao , Chong-Wah Ngo , Tao Mei

In the precision medicine era, there is a growing need for precision radiotherapy where the planned radiation dose needs to be optimally determined by considering a myriad of patient-specific information in order to ensure treatment…

Machine Learning · Statistics 2022-02-10 Wenbo Sun , Dipesh Niraula , Issam El Naqa , Randall K Ten Haken , Ivo D Dinov , Kyle Cuneo , Judy Jin

Purpose: This study evaluates the effectiveness and impact of automated order-based protocol assignment for magnetic resonance imaging (MRI) exams using natural language processing (NLP) and deep learning (DL). Methods: NLP tools were…

Machine Learning · Computer Science 2021-06-17 Andrew S. Nencka , Mohammad Sherafati , Timothy Goebel , Parag Tolat , Kevin M. Koch

Radiotherapy is a primary treatment for cancers with the aim of applying sufficient radiation dose to the planning target volume (PTV) while minimizing dose hazards to the organs at risk (OARs). Convolutional neural networks (CNNs) have…

Image and Video Processing · Electrical Eng. & Systems 2024-02-08 Lu Wen , Qihun Zhang , Zhenghao Feng , Yuanyuan Xu , Xiao Chen , Jiliu Zhou , Yan Wang

Preoperative opioid use has been reported to be associated with higher preoperative opioid demand, worse postoperative outcomes, and increased postoperative healthcare utilization and expenditures. Understanding the risk of preoperative…

Machine Learning · Computer Science 2022-05-18 Yuming Sun , Jian Kang , Chad Brummett , Yi Li

Background: Deep learning (DL)-based head and neck lymph node level (HN_LNL) autodelineation is of high relevance to radiotherapy research and clinical treatment planning but still underinvestigated in academic literature. Methods: An…

Recent development in the data-driven decision science has seen great advances in individualized decision making. Given data with individual covariates, treatment assignments and outcomes, policy makers best individualized treatment rule…

Machine Learning · Statistics 2020-06-29 Weibin Mo , Zhengling Qi , Yufeng Liu

Accurate 3D dose calculation for Pencil Beam Scanning Proton Therapy (PBSPT) is typically performed with Monte Carlo (MC) engines, but their runtimes limit adaptive workflows and repeated evaluations. Current deep-learning proton dose…

Medical Physics · Physics 2026-02-19 Mikołaj Stryja , Danny Lathouwers , Zoltán Perkó

Near infrared diffuse optical tomography (DOT) provides an imaging modality for the oxygenation of tissue. In this paper, we propose a novel machine learning algorithm based on time-domain radiative transfer equation. We use temporal…

Medical Physics · Physics 2020-11-26 Yu-ichi Takamizu , Masayuki Umemura , Hidenobu Yajima , Makito Abe , Yoko Hoshi

Positron emission tomography (PET) is widely used in various clinical applications, including cancer diagnosis, heart disease and neuro disorders. The use of radioactive tracer in PET imaging raises concerns due to the risk of radiation…

Computer Vision and Pattern Recognition · Computer Science 2017-12-13 Junshen Xu , Enhao Gong , John Pauly , Greg Zaharchuk

Objectives: A new dosimetric variable, dose dropping speed (DDS), was proposed and used to evaluate normal tissue sparing among stereotactic radiosurgery (SRS) plans with different prescription isodose lines. Methods: Forty plans were…

Medical Physics · Physics 2014-08-28 Q. Zhang , D. Zheng , Y. Lei , B. Morgan , J. Driewer , M. Zhang , S. Li , S. Zhou , W. Zhen , R. Thompson , A. Wahl , C. Lin , C. Enke

Purpose: This study explores the feasibility of dose-escalated proton beam therapy (dPBT) for Locally Advanced Pancreatic Cancer (LAPC) patients by modeling common patient scenarios using current clinically-adopted practices. Methods: Five…

Medical Physics · Physics 2025-07-30 M. A. McIntyre , J. Midson , P. Wilson , P Gorayski , C. E. Hsieh , S. W. Wu , E. Bezak

A central problem in the field of radiation therapy (RT) is how to optimally deliver dose to a patient in a way that fully accounts for anatomical position changes over time. As current RT is a static process, where beam intensities are…

Medical Physics · Physics 2019-09-04 Rodney D. Wiersma , Xinmin Liu
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