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Sharing and working on sensitive data in distributed settings from healthcare to finance is a major challenge due to security and privacy concerns. Secure multiparty computation (SMC) is a viable panacea for this, allowing distributed…

Cryptography and Security · Computer Science 2017-07-07 Abbas Acar , Z. Berkay Celik , Hidayet Aksu , A. Selcuk Uluagac , Patrick McDaniel

We developed a study design for rare disease clinical trials (RDTs) that efficiently evaluate treatments, promotes access to new treatments during treatment development, and optimizes healthcare resource utilization for future treatment…

Applications · Statistics 2016-07-04 Jian Yong , Sohaib H. Mohammad , Yan Yuan

Privacy-preserving distributed processing has recently attracted considerable attention. It aims to design solutions for conducting signal processing tasks over networks in a decentralized fashion without violating privacy. Many algorithms…

Cryptography and Security · Computer Science 2020-09-03 Qiongxiu Li , Jaron Skovsted Gundersen , Richard Heusdens , Mads Græsbøll Christensen

Privacy preserving multi-party computation has many applications in areas such as medicine and online advertisements. In this work, we propose a framework for distributed, secure machine learning among untrusted individuals. The framework…

Cryptography and Security · Computer Science 2018-11-27 Yunhui Long , Tanmay Gangwani , Haris Mughees , Carl Gunter

Countries across the globe have been pushing strict regulations on the protection of personal or private data collected. The traditional centralized machine learning method, where data is collected from end-users or IoT devices, so that it…

Computing the principal component (PC) of the adjacency matrix of an undirected graph has several applications ranging from identifying key vertices for influence maximization and controlling diffusion processes, to discovering densely…

Data Structures and Algorithms · Computer Science 2026-03-06 Alireza Khayatian , Anil Vullikanti , Aritra Konar

In recent years, machine learning techniques are widely used in numerous applications, such as weather forecast, financial data analysis, spam filtering, and medical prediction. In the meantime, massive data generated from multiple sources…

Cryptography and Security · Computer Science 2018-10-08 Wei Du , Ang Li , Qinghua Li

Symbolic Regression is a powerful data-driven technique that searches for mathematical expressions that explain the relationship between input variables and a target of interest. Due to its efficiency and flexibility, Genetic Programming…

Cryptography and Security · Computer Science 2023-07-25 Du Nguyen Duy , Michael Affenzeller , Ramin-Nikzad Langerodi

Verifying the quality of a random number generator involves performing computationally intensive statistical tests on large data sets commonly in the range of gigabytes. Limitations on computing power can restrict an end-user's ability to…

In distributed optimization, multiple parties collaborate to find an optimal solution to a problem. Privacy-preserving distributed optimization uses techniques, such as secure multi-party computation (MPC), to protect the private inputs of…

Neural and Evolutionary Computing · Computer Science 2026-05-21 Sebastian Gruber , Tobias Harzfeld , Christoph G. Schuetz , Florian Wohner , Thomas Lorünser

Practical machine learning systems often operate in multiple sequential stages, as seen in ranking and recommendation systems, which typically include a retrieval phase followed by a ranking phase. Effectively assessing prediction…

Information Retrieval · Computer Science 2025-02-04 Yunpeng Xu , Mufang Ying , Wenge Guo , Zhi Wei

An efficient paradigm for multi-party computation (MPC) are protocols structured around access to shared pre-processed computational resources. In this model, certain forms of correlated randomness are distributed to the participants prior…

Quantum Physics · Physics 2025-05-16 Maxwell Gold , Eric Chitambar

Deep learning-based Multi-Task Classification (MTC) is widely used in applications like facial attributes and healthcare that warrant strong privacy guarantees. In this work, we aim to protect sensitive information in the inference phase of…

Machine Learning · Computer Science 2021-10-08 Ren Wang , Zhe Xu , Alfred Hero

Logistic regression (LR) is a widely used classification method for modeling binary outcomes in many medical data classification tasks. Research that collects and combines datasets from various data custodians and jurisdictions can…

Machine Learning · Computer Science 2021-05-17 Ali Reza Ghavamipour , Fatih Turkmen , Xiaoqian Jian

Objective: Randomized controlled trial (RCT) results often inform clinical decision-making, but the highly curated populations of trials and the care provided during the trial are often not reflective of real-world practice. The objective…

Applications · Statistics 2024-02-26 Guanbo Wang , Ting-Wei Ernie Liao , David Furfaro , Leo Anthony Celi , Kevin Sheng-Kai Ma

In some socio-economic surveys, data are collected on sensitive or stigmatizing issues such as tax evasion, criminal conviction, drug use, etc. In such surveys, direct questioning of respondents is not of much use and the randomized…

Statistics Theory · Mathematics 2013-03-22 Mausumi Bose

Security protocols often use randomization to achieve probabilistic non-determinism. This non-determinism, in turn, is used in obfuscating the dependence of observable values on secret data. Since the correctness of security protocols is…

Cryptography and Security · Computer Science 2009-06-30 Susmit Jha

We consider a fully-decentralized scenario in which no central trusted entity exists and all clients are honest-but-curious. The state-of-the-art approaches to this problem often rely on cryptographic protocols, such as multiparty…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-10-19 Hsuan-Po Liu , Mahdi Soleymani , Hessam Mahdavifar

As one of the most popular statistical and machine learning models, logistic regression with regularization has found wide adoption in biomedicine, social sciences, information technology, and so on. These domains often involve data of…

Machine Learning · Computer Science 2016-09-28 Wenfa Li , Hongzhe Liu , Peng Yang , Wei Xie

Randomized Controlled Trials (RCTs), or A/B testing, have become the gold standard for optimizing various operational policies on online platforms. However, RCTs on these platforms typically cover a limited number of discrete treatment…

Econometrics · Economics 2026-02-06 Zhiqi Zhang , Zhiyu Zeng , Ruohan Zhan , Dennis Zhang