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With the recent advances in machine learning for quantum chemistry, it is now possible to predict the chemical properties of compounds and to generate novel molecules. Existing generative models mostly use a string- or graph-based…

Biomolecules · Quantitative Biology 2020-10-14 Vitali Nesterov , Mario Wieser , Volker Roth

Physically-motivated and mathematically robust atom-centred representations of molecular structures are key to the success of modern atomistic machine learning (ML) methods. They lie at the foundation of a wide range of methods to predict…

Atomistic simulations of matter, especially those that leverage first-principles (ab initio) electronic structure theory, provide a microscopic view of the world, underpinning much of our understanding of chemistry and materials science.…

Chemical Physics · Physics 2025-09-08 Ilyes Batatia , Philipp Benner , Yuan Chiang , Alin M. Elena , Dávid P. Kovács , Janosh Riebesell , Xavier R. Advincula , Mark Asta , Matthew Avaylon , William J. Baldwin , Fabian Berger , Noam Bernstein , Arghya Bhowmik , Filippo Bigi , Samuel M. Blau , Vlad Cărare , Michele Ceriotti , Sanggyu Chong , James P. Darby , Sandip De , Flaviano Della Pia , Volker L. Deringer , Rokas Elijošius , Zakariya El-Machachi , Fabio Falcioni , Edvin Fako , Andrea C. Ferrari , John L. A. Gardner , Mikolaj J. Gawkowski , Annalena Genreith-Schriever , Janine George , Rhys E. A. Goodall , Jonas Grandel , Clare P. Grey , Petr Grigorev , Shuang Han , Will Handley , Hendrik H. Heenen , Kersti Hermansson , Christian Holm , Cheuk Hin Ho , Stephan Hofmann , Jad Jaafar , Konstantin S. Jakob , Hyunwook Jung , Venkat Kapil , Aaron D. Kaplan , Nima Karimitari , James R. Kermode , Panagiotis Kourtis , Namu Kroupa , Jolla Kullgren , Matthew C. Kuner , Domantas Kuryla , Guoda Liepuoniute , Chen Lin , Johannes T. Margraf , Ioan-Bogdan Magdău , Angelos Michaelides , J. Harry Moore , Aakash A. Naik , Samuel P. Niblett , Sam Walton Norwood , Niamh O'Neill , Christoph Ortner , Kristin A. Persson , Karsten Reuter , Andrew S. Rosen , Louise A. M. Rosset , Lars L. Schaaf , Christoph Schran , Benjamin X. Shi , Eric Sivonxay , Tamás K. Stenczel , Viktor Svahn , Christopher Sutton , Thomas D. Swinburne , Jules Tilly , Cas van der Oord , Santiago Vargas , Eszter Varga-Umbrich , Tejs Vegge , Martin Vondrák , Yangshuai Wang , William C. Witt , Thomas Wolf , Fabian Zills , Gábor Csányi

Atomistic simulations using accurate energy functions can provide molecular-level insight into functional motions of molecules in the gas- and in the condensed phase. Together with recently developed and currently pursued efforts in…

Chemical Physics · Physics 2022-01-12 M. Meuwly

Crystalline materials, with symmetrical and periodic structures, exhibit a wide spectrum of properties and have been widely used in numerous applications across electronics, energy, and beyond. For crystalline materials discovery,…

Computational Engineering, Finance, and Science · Computer Science 2026-02-11 Zhenzhong Wang , Haowei Hua , Wanyu Lin , Ming Yang , Kay Chen Tan

An elementary understanding of the relevant length, mass and energy scales at the molecular level can be used to explain the order of magnitude of material properties such as mass density, latent heat, surface tension, elastic moduli and…

Physics Education · Physics 2014-02-26 Andrew Lucas

We develop a representation theory of categories as a means to explore characteristic structures in algebra. Characteristic structures play a critical role in isomorphism testing of groups and algebras, and their construction and…

Group Theory · Mathematics 2025-11-20 Peter A. Brooksbank , Heiko Dietrich , Joshua Maglione , E. A. O'Brien , James B. Wilson

With the rapid development of quantum technology, one of the leading applications is the simulation of chemistry. Interestingly, even before full scale quantum computers are available, quantum computer science has exhibited a remarkable…

Advances in machine learning have led to the development of foundation models for atomistic materials chemistry, enabling quantum-accurate descriptions of interatomic forces across chemically diverse compounds at reduced computational cost.…

Materials Science · Physics 2025-07-11 Balázs Póta , Paramvir Ahlawat , Gábor Csányi , Michele Simoncelli

The expansiveness of compositional phase space is too vast to fully search using current theoretical tools for many emergent problems in condensed matter physics. The reliance on a deep chemical understanding is one method to identify local…

Superconductivity · Physics 2023-01-26 Lazar Novakovic , Ashkan Salamat , Keith V. Lawler

Machine learning in atomistic materials science has grown to become a powerful tool, with most approaches focusing on atomic arrangements, typically decomposed into local atomic environments. This approach, while well-suited for…

Materials Science · Physics 2025-03-12 Austin Zadoks , Antimo Marrazzo , Nicola Marzari

Machine learning techniques have been widely employed as effective tools in addressing various engineering challenges in recent years, particularly for the challenging task of microstructure-informed materials modeling. This work provides a…

Materials Science · Physics 2024-05-29 Xiang-Long Peng , Mozhdeh Fathidoost , Binbin Lin , Yangyiwei Yang , Bai-Xiang Xu

Recent advances in (scanning) transmission electron microscopy have enabled routine generation of large volumes of high-veracity structural data on 2D and 3D materials, naturally offering the challenge of using these as starting inputs for…

Data Analysis, Statistics and Probability · Physics 2022-11-08 Ayana Ghosh , Maxim Ziatdinov , Ondrej Dyck , Bobby Sumpter , Sergei V. Kalinin

Due to the subtle balance of intermolecular interactions that govern structure-property relations, predicting the stability of crystal structures formed from molecular building blocks is a highly non-trivial scientific problem. A…

Chemical Physics · Physics 2022-12-26 Rose K. Cersonsky , Maria Pakhnova , Edgar A. Engel , Michele Ceriotti

High-throughput approximations of quantum mechanics calculations and combinatorial experiments have been traditionally used to reduce the search space of possible molecules, drugs and materials. However, the interplay of structural and…

Quantum Physics · Physics 2019-10-29 Alain Tchagang , Julio Valdés

Recent advances in atomic and nano-scale growth and characterization techniques have led to the production of modern magnetic materials and magneto-devices which reveal a range of new fascinating phenomena. The modeling of these is a tough…

Mesoscale and Nanoscale Physics · Physics 2009-09-29 S. Sanvito

A new method is presented to generate atomic structures that reproduce the essential characteristics of arbitrary material systems, phases, or ensembles. Previous methods allow one to reproduce the essential characteristics (e.g. chemical…

Materials Science · Physics 2024-09-24 James M. Goff , Coreen Mullen , Shizhong Yang , Oleg N. Starovoytov , Mitchell A. Wood

We introduce a machine-learning (ML) framework for high-throughput benchmarking of diverse representations of chemical systems against datasets of materials and molecules. The guiding principle underlying the benchmarking approach is to…

Machine Learning · Computer Science 2021-12-07 Carl Poelking , Felix A. Faber , Bingqing Cheng

We review the recent literature on the simulation of the structure and deformation of amorphous glasses, including oxide and metallic glasses. We consider simulations at different length and time scales. At the nanometer scale, we review…

Mesoscale and Nanoscale Physics · Physics 2015-05-28 David Rodney , Anne Tanguy , Damien Vandembroucq

Data-driven techniques are increasingly used to replace electronic-structure calculations of matter. In this context, a relevant question is whether machine learning (ML) should be applied directly to predict the desired properties or be…

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