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Recent evolution in deep learning has proven its value for CT-based lung nodule classification. Most current techniques are intrinsically black-box systems, suffering from two generalizability issues in clinical practice. First,…

Image and Video Processing · Electrical Eng. & Systems 2022-02-28 Hanxiao Zhang , Liang Chen , Xiao Gu , Minghui Zhang , Yulei Qin , Feng Yao , Zhexin Wang , Yun Gu , Guang-Zhong Yang

Measurement of uncertainty of predictions from machine learning methods is important across scientific domains and applications. We present, to our knowledge, the first such technique that quantifies the uncertainty of predictions from a…

Machine Learning · Statistics 2022-04-04 Alex Hagen , Karl Pazdernik , Nicole LaHaye , Marjolein Oostrom

We describe a method for verifying the output of a deep neural network for medical image segmentation that is robust to several classes of random as well as worst-case perturbations i.e. adversarial attacks. This method is based on a…

Computer Vision and Pattern Recognition · Computer Science 2023-12-21 Fahim Ahmed Zaman , Xiaodong Wu , Weiyu Xu , Milan Sonka , Raghuraman Mudumbai

The uncertainty measurement of classifiers' predictions is especially important in applications such as medical diagnoses that need to ensure limited human resources can focus on the most uncertain predictions returned by machine learning…

Machine Learning · Computer Science 2019-07-18 Xuchao Zhang , Fanglan Chen , Chang-Tien Lu , Naren Ramakrishnan

We propose a method to incorporate the intensity information of a target lesion on CT scans in training segmentation and detection networks. We first build an intensity-based lesion probability (ILP) function from an intensity histogram of…

Image and Video Processing · Electrical Eng. & Systems 2023-07-13 Seung Yeon Shin , Thomas C. Shen , Ronald M. Summers

We consider the problem of uncertainty estimation in the context of (non-Bayesian) deep neural classification. In this context, all known methods are based on extracting uncertainty signals from a trained network optimized to solve the…

Machine Learning · Computer Science 2019-04-25 Yonatan Geifman , Guy Uziel , Ran El-Yaniv

The detection of malware is a critical task for the protection of computing environments. This task often requires extremely low false positive rates (FPR) of 0.01% or even lower, for which modern machine learning has no readily available…

Machine Learning · Computer Science 2021-09-07 Andre T. Nguyen , Edward Raff , Charles Nicholas , James Holt

In the last few years, deep learning classifiers have shown promising results in image-based medical diagnosis. However, interpreting the outputs of these models remains a challenge. In cancer diagnosis, interpretability can be achieved by…

Computer Vision and Pattern Recognition · Computer Science 2021-06-16 Kangning Liu , Yiqiu Shen , Nan Wu , Jakub Chłędowski , Carlos Fernandez-Granda , Krzysztof J. Geras

Reliably detecting diseases using relevant biological information is crucial for real-world applicability of deep learning techniques in medical imaging. We debias deep learning models during training against unknown bias - without…

Computer Vision and Pattern Recognition · Computer Science 2022-06-09 Simon Langer , Oliver Taubmann , Felix Denzinger , Andreas Maier , Alexander Mühlberg

Since the rise of deep learning, many computer vision tasks have seen significant advancements. However, the downside of deep learning is that it is very data-hungry. Especially for segmentation problems, training a deep neural net requires…

Computer Vision and Pattern Recognition · Computer Science 2021-10-13 Robby Neven , Davy Neven , Bert De Brabandere , Marc Proesmans , Toon Goedemé

Deep neural networks are powerful tools to detect hidden patterns in data and leverage them to make predictions, but they are not designed to understand uncertainty and estimate reliable probabilities. In particular, they tend to be…

Machine Learning · Statistics 2022-11-10 Bat-Sheva Einbinder , Yaniv Romano , Matteo Sesia , Yanfei Zhou

We propose a novel convolutional neural network for lesion detection from weak labels. Only a single, global label per image - the lesion count - is needed for training. We train a regression network with a fully convolutional architecture…

Computer Vision and Pattern Recognition · Computer Science 2017-10-31 Florian Dubost , Gerda Bortsova , Hieab Adams , Arfan Ikram , Wiro Niessen , Meike Vernooij , Marleen De Bruijne

Trained using only image class label, deep weakly supervised methods allow image classification and ROI segmentation for interpretability. Despite their success on natural images, they face several challenges over histology data where ROI…

Image and Video Processing · Electrical Eng. & Systems 2022-05-13 Soufiane Belharbi , Jérôme Rony , Jose Dolz , Ismail Ben Ayed , Luke McCaffrey , Eric Granger

Deep neural networks are increasingly being used for the analysis of medical images. However, most works neglect the uncertainty in the model's prediction. We propose an uncertainty-aware deep kernel learning model which permits the…

Machine Learning · Computer Science 2021-06-11 Zhiliang Wu , Yinchong Yang , Jindong Gu , Volker Tresp

In many screening applications, the primary goal of a radiologist or assisting artificial intelligence is to rule out certain findings. The classifiers built for such applications are often trained on large datasets that derive labels from…

Image and Video Processing · Electrical Eng. & Systems 2019-06-25 Alexandros Karargyris , Ken C. L. Wong , Joy T. Wu , Mehdi Moradi , Tanveer Syeda-Mahmood

In this paper, we introduced the novel concept of advisor network to address the problem of noisy labels in image classification. Deep neural networks (DNN) are prone to performance reduction and overfitting problems on training data with…

Computer Vision and Pattern Recognition · Computer Science 2024-08-19 Simone Ricci , Tiberio Uricchio , Alberto Del Bimbo

Liver lesion segmentation is an important step for liver cancer diagnosis, treatment planning and treatment evaluation. LiTS (Liver Tumor Segmentation Challenge) provides a common testbed for comparing different automatic liver lesion…

Computer Vision and Pattern Recognition · Computer Science 2017-07-05 Xiao Han

Accurate and reliable tumor segmentation is essential in medical imaging analysis for improving diagnosis, treatment planning, and monitoring. However, existing segmentation models often lack robust mechanisms for quantifying the…

Image and Video Processing · Electrical Eng. & Systems 2025-03-14 Seyed Sina Ziaee , Farhad Maleki , Katie Ovens

Deep learning models (DLMs) frequently achieve accurate segmentation and classification of tumors from medical images. However, DLMs lacking feedback on their image segmentation mechanisms, such as Dice coefficients and confidence in their…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Elhoucine Elfatimi , Pratik Shah

The use of deep learning for medical imaging has seen tremendous growth in the research community. One reason for the slow uptake of these systems in the clinical setting is that they are complex, opaque and tend to fail silently. Outside…

Computer Vision and Pattern Recognition · Computer Science 2018-07-03 Terrance DeVries , Graham W. Taylor