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The thermodynamic uncertainty relation is a universal trade-off relation connecting the precision of a current with the average dissipation at large times. For continuous time Markov chains (also called Markov jump processes) this relation…

Statistical Mechanics · Physics 2019-09-04 A. C. Barato , R. Chetrite , A. Faggionato , D. Gabrielli

Two widely used model-free lower bounds on the steady-state entropy production rate of a continuous-time Markov jump process are the thermodynamic uncertainty relation (TUR) bound $\sigma_\text{TUR}$, derived from the mean and variance of a…

Statistical Mechanics · Physics 2026-01-08 Jie Gu

Machine learning models have emerged as a very effective strategy to sidestep time-consuming electronic-structure calculations, enabling accurate simulations of greater size, time scale and complexity. Given the interpolative nature of…

Physical systems that power motion and create structure in a fixed amount of time dissipate energy and produce entropy. Whether living or synthetic, systems performing these dynamic functions must balance dissipation and speed. Here, we…

Statistical Mechanics · Physics 2020-12-18 Schuyler B. Nicholson , Luis Pedro Garcia-Pintos , Adolfo del Campo , Jason R. Green

Thermodynamic uncertainty relations (TURs) are general lower bounds on the size of fluctutations of dynamical observables. They have important consequences, one being that the precision of estimation of a current is limited by the amount of…

Statistical Mechanics · Physics 2022-10-12 George Bakewell-Smith , Federico Girotti , Mădălin Guţă , Juan P. Garrahan

Enhancing the precision of a thermodynamic process inevitably necessitates a thermodynamic cost. This notion was recently formulated as the thermodynamic uncertainty relation, which states that the lower bound on the relative variance of…

Quantum Physics · Physics 2025-11-14 Yoshihiko Hasegawa

We provide a minimal strategy for the quantitative analysis of a large class of non-equilibrium systems in a {statistically} steady state using the short-time Thermodynamic Uncertainty Relation (TUR). From short-time trajectory data…

Universal relations that characterize the fluctuations of nonequilibrium systems are of fundamental importance. The thermodynamic and kinetic uncertainty relations impose upper bounds on the precision of currents solely by total entropy…

Statistical Mechanics · Physics 2022-08-30 Tomohiro Nishiyama

Nonequilibrium steady state of isothermal biochemical cycle kinetics has been extensively studied, but much less investigated under non-isothermal conditions. However, once the heat exchange between subsystems is rather slow, the isothermal…

Chemical Physics · Physics 2016-10-11 Xiao Jin , Hao Ge

The past twenty years have seen a resurgence of interest in nonequilibrium thermodynamics, thanks to advances in the theory of stochastic processes and in their thermodynamic interpretation. Fluctuation theorems provide fundamental…

Statistical Mechanics · Physics 2017-11-16 Robert Marsland , Jeremy England

Thermodynamic uncertainty relations (TURs) relate precision to the dissipation rate, yet the inequalities can be far from saturation. Indeed, in catenane molecular motor simulations, we record precision far below the TUR limit. We further…

Statistical Mechanics · Physics 2026-01-14 Alex Albaugh , Rueih-Sheng Fu , Geyao Gu , Todd R. Gingrich

Nonequilibrium current fluctuations represent one of the central topics in nonequilibrium physics. The thermodynamic uncertainty relation (TUR) is widely acclaimed for rigorously establishing a lower bound on current fluctuations, expressed…

Statistical Mechanics · Physics 2025-12-09 Van Tuan Vo , Andreas Dechant , Keiji Saito

We derive a Thermodynamic Uncertainty Relation bounding the mean squared displacement of a Gaussian process with memory, driven out of equilibrium by unbalanced thermal baths and/or by external forces. Our bound is tighter with respect to…

Statistical Mechanics · Physics 2023-05-23 Andrea Plati , Andrea Puglisi , Alessandro Sarracino

The thermodynamic uncertainty relation posits that higher thermodynamic costs are essential for a system to function with greater precision. Recent discussions have expanded thermodynamic uncertainty relations beyond classical…

Quantum Physics · Physics 2023-12-13 Yoshihiko Hasegawa

Thermodynamic uncertainty relations (TURs) bound the precision of currents by entropy production, but quantum transport of noncommuting (non-Abelian) charges challenges standard formulations because different charge components cannot be…

Quantum Physics · Physics 2026-01-01 Domingos S. P. Salazar

Uncertainty quantification (UQ) is the process of systematically determining and characterizing the degree of confidence in computational model predictions. In the context of systems biology, especially with dynamic models, UQ is crucial…

Machine Learning · Statistics 2024-10-29 Alberto Portela , Julio R. Banga , Marcos Matabuena

The thermodynamic uncertainty relation is a prominent result in stochastic thermodynamics that provides a bound on the fluctuations of any thermodynamic flux, also known as current, in terms of the average rate of entropy production. Such…

Statistical Mechanics · Physics 2021-12-22 Taylor Wampler , Andre C Barato

The thermodynamic uncertainty relation (TUR) quantifies a relationship between current fluctuations and dissipation in out-of-equilibrium overdamped Langevin dynamics, making it a natural counterpart of the fluctuation-dissipation theorem…

Statistical Mechanics · Physics 2022-10-04 Rueih-Sheng Fu , Todd R. Gingrich

In the real world, one almost never knows the parameters of a thermodynamic process to infinite precision. Reflecting this, here we investigate how to extend stochastic thermodynamics to systems with uncertain parameters, including…

Statistical Mechanics · Physics 2021-03-17 Jan Korbel , David H. Wolpert

For Markov processes over discrete configurations, an asymptotic bound on the uncertainty of stochastic fluxes is derived in terms of the harmonic mean of decay rates with respect to the stationary distribution. This bound is necessarily…

Statistical Mechanics · Physics 2024-07-16 Katarzyna Macieszczak
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