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We develop numerical methods for reaction-diffusion systems based on the equations of fluctuating hydrodynamics (FHD). While the FHD formulation is formally described by stochastic partial differential equations (SPDEs), it becomes similar…

Fluid Dynamics · Physics 2018-01-17 Changho Kim , Andy Nonaka , John B. Bell , Alejandro L. Garcia , Aleksandar Donev

This paper proposes a control theoretic framework to model and analyze the self-organized pattern formation of molecular concentrations in biomolecular communication networks, emerging applications in synthetic biology. In biomolecular…

Molecular Networks · Quantitative Biology 2019-01-08 Yutaka Hori , Hiroki Miyazako , Soichiro Kumagai , Shinji Hara

Reaction-diffusion systems where transition rates exhibit quenched disorder are common in physical and chemical systems. We study pair reactions on a periodic two-dimensional lattice, including continuous deposition and spontaneous…

Disordered Systems and Neural Networks · Physics 2010-11-10 A. Wolff , I. Lohmar , J. Krug , Y. Frank , O. Biham

We consider two volume-surface reaction-diffusion systems arising from cell biology. The first system describes the localisation of the protein Lgl in the asymmetric division of Drosophila SOP stem cells, while the second system models the…

Analysis of PDEs · Mathematics 2016-12-22 Klemens Fellner , Bao Quoc Tang

In this paper we study pattern formation arising in a system of a single reaction-diffusion equation coupled with subsystem of ordinary differential equations, describing spatially-distributed growth of clonal populations of precancerous…

Tissues and Organs · Quantitative Biology 2019-05-14 Yuriy Golovaty , Anna Marciniak-Czochra , Mariya Ptashnyk

The reversible reactions like A+B <-> C in the many-component diffusive system affect the diffusive properties of the constituents. The effective conjugation of irreversible processes of different dimensionality takes place due to the…

Other Condensed Matter · Physics 2007-05-23 Serge Shpyrko , Vladimir M. Sysoev

Many mathematical models for biological phenomena, such as the spread of diseases, are based on reaction-diffusion equations for densities of interacting cell populations. We present a consistent derivation of reaction-diffusion equations…

Analysis of PDEs · Mathematics 2026-02-23 Marzia Bisi , Davide Cusseddu , Ana Jacinta Soares , Romina Travaglini

In this article we propose a unified framework in order to study reaction-diffusion systems containing self- and cross-diffusion using a free energy approach. This framework naturally leads to the formulation of an energy law, and to a…

Computational Physics · Physics 2021-10-12 Benjamin Aymard

The reaction-diffusion waves of proteins are known to be involved in fundamental cellular functions, such as cell migration, cell division, and vesicular transportation. In some of these phenomena, pattern formation on the membranes is…

Soft Condensed Matter · Physics 2021-07-16 Naoki Tamemoto , Hiroshi Noguchi

Structural prediction of protein-protein interactions is important to understand the molecular basis of cellular interactions, but it still faces major challenges when significant conformational changes are present. We propose a generative…

Computational Engineering, Finance, and Science · Computer Science 2025-09-26 Rujie Yin , Yang Shen

Reaction diffusion systems describe the behaviour of dynamic, interacting, particulate systems. Quantum stochastic processes generalise Brownian motion and Poisson processes, having operator valued It\^{o} calculus machinery. Here it is…

Mathematical Physics · Physics 2023-05-31 Chris D Greenman

Spontaneous pattern formation in homogeneous systems is ubiquitous in nature. Although Turing demonstrated that spatial patterns can emerge in reaction-diffusion (RD) systems when the homogeneous state becomes linearly unstable, it remains…

Biological Physics · Physics 2024-08-20 Shuonan Wu , Bing Yu , Yuhai Tu , Lei Zhang

This study investigates an SEIS PDE model with a free boundary, which captures the dynamics of epidemic transmission, including diseases like COVID-19. This parabolic PDE system is analyzed in a rotationally symmetric domain, and the…

Analysis of PDEs · Mathematics 2025-11-11 Aesol Jeon , Ki-Ahm Lee

We present a mathematical study for the development of multiple sclerosis based on a reaction-diffusion system. The model describes interactions among different populations of human cells, motion of immune cells stimulated by cytokines,…

Tissues and Organs · Quantitative Biology 2026-01-07 Romina Travaglini

We address the question: Why may reaction-diffusion equations with hysteretic nonlinearities become ill-posed and how to amend this? To do so, we discretize the spatial variable and obtain a lattice dynamical system with a hysteretic…

Analysis of PDEs · Mathematics 2017-11-28 Pavel Gurevich , Sergey Tikhomirov

We develop a mesoscopic modeling framework for diffusion in a crowded environment, particularly targeting applications in the modeling of living cells. Through homogenization techniques we effectively coarse-grain a detailed microscopic…

Subcellular Processes · Quantitative Biology 2018-09-19 Stefan Engblom , Per Lötstedt , Lina Meinecke

Stochastic reaction-diffusion processes may be presented in terms of integrable quantum chains and can be used to describe various biological and chemical systems. Exploiting the integrability of the models one finds in some cases good…

Condensed Matter · Physics 2007-05-23 Gunter M. Schütz

We discovered a class of self-similar solutions in nonlinear models describing the formation of morphogen gradients, the concentration fields of molecules acting as spatial regulators of cell differention in developing tissues. These models…

Quantitative Methods · Quantitative Biology 2015-05-28 Cyrill B. Muratov , Peter V. Gordon , Stanislav Y. Shvartsman

Reaction-diffusion PDEs and particle-based stochastic reaction-diffusion (PBSRD) models are commonly-used approaches for modeling the spatial dynamics of chemical and biological systems. Standard reaction-diffusion PDE models ignore the…

Analysis of PDEs · Mathematics 2021-06-02 Samuel A Isaacson , Jingwei Ma , Konstantinos Spiliopoulos

We introduce a simple nonequilibrium model for a driven diffusive system with nonconservative reaction kinetics which exhibits ergodicity breaking and hysteresis in one dimension. These phenomena can be understood through a description of…

Statistical Mechanics · Physics 2009-11-10 A. Rakos , M. Paessens , G. M. Schuetz