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The COVID-19 pandemic, caused by SARS-CoV-2, highlighted the critical need for accurate prediction of disease severity to optimize healthcare resource allocation and patient management. The spike protein, which facilitates viral entry into…

Machine Learning · Computer Science 2025-06-02 Caio Cheohen , Vinnícius M. S. Gomes , Manuela L. da Silva

Coronavirus disease 2019 (COVID-19) is an ongoing global pandemic in over 200 countries and territories, which has resulted in a great public health concern across the international community. Analysis of X-ray imaging data can play a…

Image and Video Processing · Electrical Eng. & Systems 2021-04-02 Lucy Nwosu , Xiangfang Li , Lijun Qian , Seungchan Kim , Xishuang Dong

The accurate prediction of B-cell epitopes is critical for guiding vaccine development against infectious diseases, including SARS and COVID-19. This study explores the use of a deep neural network (DNN) model to predict B-cell epitopes for…

Machine Learning · Computer Science 2024-12-03 Xinyu Shi , Yixin Tao , Shih-Chi Lin

The intra- and inter-species genetic diversity of bacteria and the absence of 'reference', or the most representative, sequences of individual species present a significant challenge for sequence-based identification. The aims of this study…

Genomics · Quantitative Biology 2023-12-01 Manal Helal , Fanrong Kong , Sharon C. A. Chen , Michael Bain , Richard Christen , Vitali Sintchenko

RaTG13 is the closest related coronavirus genome phylogenetically to SARS-CoV-2, consequently understanding its provenance is of key importance to understanding the origin of the COVID-19 pandemic. The RaTG13 NGS dataset is attributed to a…

Genomics · Quantitative Biology 2021-11-23 Steven E Massey

We propose a mathematical model with five compartments for the SARS-CoV-2 transmission: susceptible $S$, undetected infected asymptomatic $A$, undetected infected symptomatic $I$, confirmed positive and isolated $L$, and recovered $ R$, for…

Optimization and Control · Mathematics 2020-09-29 Gabriela Marinoschi

Coronavirus (COVID-19) emerged towards the end of 2019. World Health Organization (WHO) was identified it as a global epidemic. Consensus occurred in the opinion that using Computerized Tomography (CT) techniques for early diagnosis of…

Image and Video Processing · Electrical Eng. & Systems 2020-04-09 Umut Ozkaya , Saban Ozturk , Mucahid Barstugan

Background: During 2021 several new variants of the SARS-CoV-2 virus appeared with both increased levels of transmissibility and virulence with respect to the original wild variant. The Delta (B.1.617.2) variation, first seen in India,…

Physics and Society · Physics 2021-08-17 William A. Barletta

We analyze the time series data of number of districts or cities in India that are affected by COVID-19 from March 01, 2020 to April 17, 2020. We study the data in the framework of time series network data. The networks are defined by using…

Social and Information Networks · Computer Science 2020-04-28 Pradumn Kumar Pandey , Bibhas Adhikari

This paper introduces a lossless data compression competition that benchmarks solutions (computer programs) by the compressed size of the 44,981 concatenated SARS-CoV-2 sequences, with a total uncompressed size of 1,339,868,341 bytes. The…

Databases · Computer Science 2020-12-23 Innar Liiv

Corona VIrus Disease abbreviated as COVID-19 is a novel virus which is initially identified in Wuhan of China in December of 2019 and now this deadly disease has spread all over the world. According to World Health Organization (WHO), a…

Machine Learning · Computer Science 2023-08-10 Mamata Das , P. J. A. Alphonse , Selvakumar K

Novel Coronavirus disease (COVID-19) is an extremely contagious and quickly spreading Coronavirus infestation. Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS), which outbreak in 2002 and 2011, and the…

Image and Video Processing · Electrical Eng. & Systems 2021-06-02 Anas Tahir , Yazan Qiblawey , Amith Khandakar , Tawsifur Rahman , Uzair Khurshid , Farayi Musharavati , M. T. Islam , Serkan Kiranyaz , Muhammad E. H. Chowdhury

COVID-19, since emerged in Wuhan, China, has been a major concern due to its high infection rate, leaving more than one million infected people around the world. Huge number of studies tried to reveal the structure of the SARS-CoV-2…

Biological Physics · Physics 2020-04-07 Muhamed Amin , Mariam K. Sorour , Amal Kasry

Predicting protein secondary structure is a fundamental problem in protein structure prediction. Here we present a new supervised generative stochastic network (GSN) based method to predict local secondary structure with deep hierarchical…

Quantitative Methods · Quantitative Biology 2014-03-07 Jian Zhou , Olga G. Troyanskaya

Background. During 2021, the COVID-19 pandemic was characterized by the emergence of lineages with increased fitness. For most of these variants, quantitative information is scarce on epidemiological quantities such as the incubation period…

The SARS-CoV-2 pandemic has led to a significant emergence of highly mutated forms of viruses with a great ability to adapt to the human host. Some mutations resulted in changes in the amino acid sequences of viral proteins, including the…

During a virus's evolution,various regions of the genome are subjected to distinct levels of functional constraints.Combined with factors like codon bias and DNA repair efficiency,these constraints contribute to unique mutation patterns…

Quantitative Methods · Quantitative Biology 2024-12-25 Vishwajeet Marathe , Deewan Bajracharya , Changhui Yan

The emergence of SARS-CoV-2 variants of concern endangers the long-term control of COVID-19, especially in countries with limited genomic surveillance. In this work, we explored genomic drivers of contagion in Chile. We sequenced 3443…

One regards spaces of trees as stratified spaces, to study distributions of phylogenetic trees. Stratified spaces with may have cycles, however spaces of trees with a fixed number of leafs are contractible. Spaces of trees with three leafs,…

Methodology · Statistics 2021-06-16 Chen Shen , Vic Patrangenaru , Roland Moore

Background: Rapid testing for an infection is paramount during a pandemic to prevent continued viral spread and excess morbidity and mortality. This study aimed to determine whether alternative testing strategies based on sample pooling can…

Populations and Evolution · Quantitative Biology 2021-01-27 Timo de Wolff , Dirk Pflüger , Michael Rehme , Janin Heuer , Martin-Immanuel Bittner
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