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We propose a topological framework for memory and inference grounded in the structure of spike-timing dynamics, persistent homology, and the Context-Content Uncertainty Principle (CCUP). Starting from the observation that polychronous…

Neurons and Cognition · Quantitative Biology 2025-08-19 Xin Li

Different brain areas, such as the cortex and, more specifically, the prefrontal cortex, show great recurrence in their connections, even in early sensory areas. {Several approaches and methods based on trained networks have been proposed…

Neurons and Cognition · Quantitative Biology 2022-04-25 Cecilia Jarne

Replay in neural networks involves training on sequential data with memorized samples, which counteracts forgetting of previous behavior caused by non-stationarity. We present a method where these auxiliary samples are generated on the fly,…

Machine Learning · Computer Science 2020-12-15 Xu Ji , Joao Henriques , Tinne Tuytelaars , Andrea Vedaldi

In this work we study, analytically and employing Monte Carlo simulations, the influence of the competition between several activity-dependent synaptic processes, such as short-term synaptic facilitation and depression, on the maximum…

Neurons and Cognition · Quantitative Biology 2010-07-23 Jorge F. Mejias , Joaquin J. Torres

Recurrent neural networks (RNNs) trained on neuroscience-inspired tasks offer powerful models of brain computation. However, typical training paradigms rely on open-loop, supervised settings, whereas real-world learning unfolds in…

Machine Learning · Computer Science 2025-11-07 Yoav Ger , Omri Barak

A core challenge in the interpretation of deep neural networks is identifying commonalities between the underlying algorithms implemented by distinct networks trained for the same task. Motivated by this problem, we introduce DYNAMO, an…

Machine Learning · Computer Science 2023-03-01 Jordan Cotler , Kai Sheng Tai , Felipe Hernández , Blake Elias , David Sussillo

Recurrent neural networks (RNNs) can implement complex computations by leveraging a range of dynamics, such as oscillations, attractors, and transient trajectories. A growing body of work has highlighted the emergence of phase codes, a type…

Neurons and Cognition · Quantitative Biology 2025-12-02 Keith T. Murray

Metastable brain dynamics are characterized by abrupt, jump-like modulations so that the neural activity in single trials appears to unfold as a sequence of discrete, quasi-stationary states. Evidence that cortical neural activity unfolds…

Neurons and Cognition · Quantitative Biology 2019-06-20 Giancarlo La Camera , Alfredo Fontanini , Luca Mazzucato

Associative memories in the brain receive and store patterns of activity registered by the sensory neurons, and are able to retrieve them when necessary. Due to their importance in human intelligence, computational models of associative…

Machine Learning · Computer Science 2021-09-17 Tommaso Salvatori , Yuhang Song , Yujian Hong , Simon Frieder , Lei Sha , Zhenghua Xu , Rafal Bogacz , Thomas Lukasiewicz

Large-scale recurrent networks have drawn increasing attention recently because of their capabilities in modeling a large variety of real-world phenomena and physical mechanisms. This paper studies how to identify all authentic connections…

Machine Learning · Statistics 2015-06-23 Yiyuan She , Yuejia He , Dapeng Wu

Decoding stimuli or behaviour from recorded neural activity is a common approach to interrogate brain function in research, and an essential part of brain-computer and brain-machine interfaces. Reliable decoding even from small neural…

Neurons and Cognition · Quantitative Biology 2023-01-06 Justin Jude , Matthew G. Perich , Lee E. Miller , Matthias H. Hennig

Recurrent neural networks (RNNs) provide a theoretical framework for understanding computation in biological neural circuits, yet classical results, such as Hopfield's model of associative memory, rely on symmetric connectivity that…

Disordered Systems and Neural Networks · Physics 2026-02-17 Ramón Nartallo-Kaluarachchi , Renaud Lambiotte , Alain Goriely

The ability to learn continuously in artificial neural networks (ANNs) is often limited by catastrophic forgetting, a phenomenon in which new knowledge becomes dominant. By taking mechanisms of memory encoding in neuroscience (aka. engrams)…

Machine Learning · Computer Science 2025-03-28 Isabelle Aguilar , Luis Fernando Herbozo Contreras , Omid Kavehei

Real-world networks in technology, engineering and biology often exhibit dynamics that cannot be adequately reproduced using network models given by smooth dynamical systems and a fixed network topology. Asynchronous networks give a…

Dynamical Systems · Mathematics 2017-02-07 Christian Bick , Michael Field

Learning to produce spatiotemporal sequences is a common task that the brain has to solve. The same neural substrate may be used by the brain to produce different sequential behaviours. The way the brain learns and encodes such tasks…

Neurons and Cognition · Quantitative Biology 2020-07-01 Amadeus Maes , Mauricio Barahona , Claudia Clopath

Decomposing knowledge into interchangeable pieces promises a generalization advantage when there are changes in distribution. A learning agent interacting with its environment is likely to be faced with situations requiring novel…

Machine Learning · Computer Science 2021-05-20 Kanika Madan , Nan Rosemary Ke , Anirudh Goyal , Bernhard Schölkopf , Yoshua Bengio

Multiscale stochastic dynamical systems have been widely adopted to a variety of scientific and engineering problems due to their capability of depicting complex phenomena in many real world applications. This work is devoted to…

Machine Learning · Statistics 2024-01-02 Lingyu Feng , Ting Gao , Min Dai , Jinqiao Duan

The paper explores the capability of continuous-time recurrent neural networks to store and recall precisely timed scores of spike trains. We show (by numerical experiments) that this is indeed possible: within some range of parameters, any…

Neural and Evolutionary Computing · Computer Science 2025-07-29 Hugo Aguettaz , Hans-Andrea Loeliger

The design of fluid channel structures of reactors or separators of chemical processes is key to enhancing the mass transfer processes inside the devices. However, the systematic design of channel topological structures is difficult for…

Fluid Dynamics · Physics 2025-03-07 Chenhui Kou , Yuhui Yin , Min Zhu , Shengkun Jia , Yiqing Luo , Xigang Yuana , Lu Lu

A main concern in cognitive neuroscience is to decode the overt neural spike train observations and infer latent representations under neural circuits. However, traditional methods entail strong prior on network structure and hardly meet…

Neurons and Cognition · Quantitative Biology 2019-11-22 Zhijie Chen , Junchi Yan , Longyuan Li , Xiaokang Yang
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