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Non-rigid registration is a key component in soft-tissue navigation. We focus on laparoscopic liver surgery, where we register the organ model obtained from a preoperative CT scan to the intraoperative partial organ surface, reconstructed…

Image and Video Processing · Electrical Eng. & Systems 2020-06-01 Micha Pfeiffer , Carina Riediger , Stefan Leger , Jens-Peter Kühn , Danilo Seppelt , Ralf-Thorsten Hoffmann , Jürgen Weitz , Stefanie Speidel

This study employs micro-computed tomography (micro-CT) to unravel the geometrical intricacies of the rat urinary bladder wall during various states of ex-vivo filling, contrasting markedly with the commonly held idealizations of uniform…

Medical Physics · Physics 2024-06-03 Fatemeh Azari , Anne M. Robertson , Lori A. Birder

The renal vasculature, acting as a resource distribution network, plays an important role in both the physiology and pathophysiology of the kidney. However, no imaging techniques allow an assessment of the structure and function of the…

Computational Engineering, Finance, and Science · Computer Science 2023-05-11 Peidi Xu , Niels-Henrik Holstein-Rathlou , Stinne Byrholdt Søgaard , Carsten Gundlach , Charlotte Mehlin Sørensen , Kenny Erleben , Olga Sosnovtseva , Sune Darkner

Diffusion-weighted magnetic resonance imaging (DW-MRI) is a powerful, non-invasive tool for detecting and characterizing abdominal lesions to facilitate early diagnosis, but respiratory motion during a scan reduces image quality and…

Image and Video Processing · Electrical Eng. & Systems 2024-11-19 Michelle Su , Cemre Ariyurek , Serge Vasylechko , Onur Afacan , Sila Kurugol

We propose multiMap, a single scan that can generate several quantitative maps simultaneously. The sequence acquires multiple images in a time-efficient manner, which can be modeled for T_2, T2*, main- and transmit-field inhomogeneity,…

Image and Video Processing · Electrical Eng. & Systems 2020-08-04 Nicholas Dwork , Adam B. Kerr , Ethan M. I. Johnson , Corey A. Baron , Shreyas S. Vasanawala , Peder E. Z. Larson , Adam M. Bush , John Pauly

Proton FLASH therapy leverages ultra-high dose-rate radiation to enhance the sparing of organs at risk without compromising tumor control probability. To prepare for the delivery of high doses to targets, we aim to develop a deep…

Intensity modulated radiotherapy (IMRT) is one of the most common modalities for treating cancer patients. One of the biggest challenges is precise treatment delivery that accounts for varying motion patterns originating from…

Computer Vision and Pattern Recognition · Computer Science 2023-03-15 Matej Gazda , Peter Drotar , Liset Vazquez Romaguera , Samuel Kadoury

Purpose: To develop a fat-water separation approach that corrects bipolar readout gradient induced effects, without additional scans, that is compatible with any fat-water separation method. Theory and Methods: The proposed approach…

Medical Physics · Physics 2025-05-20 Jorge Campos Pazmino , Renée-Claude Bider , Véronique Fortier , Ives R. Levesque

The aim of this paper is to establish a nonlinear variational approach to the reconstruction of moving density images from indirect dynamic measurements. Our approach is to model the dynamics as a hyperelastic deformation of an initial…

Numerical Analysis · Mathematics 2015-12-01 Martin Burger , Jan Modersitzki , Sebastian Suhr

Magnetic resonance elastography is a motion-sensitive image modality that allows to measure in vivo tissue displacement fields in response to mechanical excitations. This paper investigates a data assimilation approach for reconstructing…

Purpose: A novel subspace-based reconstruction method for frequency-modulated balanced steady-state free precession (fmSSFP) MRI is presented. In this work, suitable data acquisition schemes, subspace sizes, and efficiencies for banding…

We present an indirect signal processing-based measurement method for biological quantities in humans that cannot be directly measured. We develop the method by focusing on estimating hepatic enzyme and drug transporter activity through…

Quantitative Methods · Quantitative Biology 2021-01-01 Yoko Franchetti , Thomas D. Nolin , Franz Franchetti

Quantitative imaging in MRI usually involves acquisition and reconstruction of a series of images at multi-echo time points, which possibly requires more scan time and specific reconstruction technique compared to conventional qualitative…

Signal Processing · Electrical Eng. & Systems 2021-03-11 Jinwei Zhang , Hang Zhang , Chao Li , Pascal Spincemaille , Mert Sabuncu , Thanh D. Nguyen , Yi Wang

Objectives: The role of advanced diffusion-weighted imaging (DWI) in chronic liver disease (CLD) has not been fully studied. Chronic liver disease (CLD) is a progressive deterioration of liver functions, caused by one or more etiology. This…

Tissues and Organs · Quantitative Biology 2025-09-10 Jiqing Huang , Benjamin Leporq , Valérie Hervieu , Sophie Gaillard , Jerome Dumortier , Olivier Beuf , Hélène Ratiney

Staging of liver fibrosis is important in the diagnosis and treatment planning of patients suffering from liver diseases. Current deep learning-based methods using abdominal magnetic resonance imaging (MRI) usually take a sub-region of the…

Computer Vision and Pattern Recognition · Computer Science 2023-06-22 Zheyao Gao , Yuanye Liu , Fuping Wu , NanNan Shi , Yuxin Shi , Xiahai Zhuang

Accurate three-dimensional (3D) reconstruction of cardiac chamber motion from time-resolved medical imaging modalities is of growing interest in both the clinical and biomechanical fields. Despite recent advancement, the cardiac motion…

Medical Physics · Physics 2025-04-18 Francesco Capuano , Yue-Hin Loke , Ibrahim Yildiran , Laura Olivieri , Elias Balaras

Manually tracing regions of interest (ROIs) within the liver is the de facto standard method for measuring liver attenuation on computed tomography (CT) in diagnosing nonalcoholic fatty liver disease (NAFLD). However, manual tracing is…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Yuankai Huo , James G. Terry , Jiachen Wang , Sangeeta Nair , Thomas A. Lasko , Barry I. Freedman , J. Jeffery Carr , Bennett A. Landman

Image registration is an ill-posed inverse problem which often requires regularisation on the solution space. In contrast to most of the current approaches which impose explicit regularisation terms such as smoothness, in this paper we…

Image and Video Processing · Electrical Eng. & Systems 2020-07-09 Chen Qin , Shuo Wang , Chen Chen , Huaqi Qiu , Wenjia Bai , Daniel Rueckert

Motion has been a challenge for magnetic resonance (MR) imaging ever since the MR has been invented. Especially in volumetric imaging of thoracic and abdominal organs, motion-awareness is essential for reducing motion artifacts in the final…

Image and Video Processing · Electrical Eng. & Systems 2019-08-27 Christoph Jud , Damien Nguyen , Alina Giger , Robin Sandkühler , Miriam Krieger , Tony Lomax , Rares Salomir , Oliver Bieri , Philippe C. Cattin

Diagnostic ultrasound is a versatile and practical tool in the abdomen, and is particularly vital toward the detection and mitigation of early-stage non-alcoholic fatty liver disease (NAFLD). However, its performance in those with obesity…

Signal Processing · Electrical Eng. & Systems 2024-05-14 Scott Schoen , Viksit Kumar , Yuyang Gu , Sunethra Dayavansha , Rimon Tadross , Mike Washburn , Kai Thomenius , Anthony E. Samir
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