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Molecular dynamics (MD) simulation is one of the past decade's most important tools for enabling biology scientists and researchers to explore human health and diseases. However, due to the computation complexity of the MD algorithm, it…

Computational Physics · Physics 2016-11-15 Jason Cong , Zhenman Fang , Hassan Kianinejad , Peng Wei

FPGA-based data processing in datacenters is increasing in popularity due to the demands of modern workloads and the ensuing necessity for specialization in hardware. Driven by this trend, vendors are rapidly adapting reconfigurable devices…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-04-06 Kaan Kara , Christoph Hagleitner , Dionysios Diamantopoulos , Dimitris Syrivelis , Gustavo Alonso

Space missions are becoming increasingly ambitious, necessitating high-performance onboard spacecraft computing systems. In response, field-programmable gate arrays (FPGAs) have garnered significant interest due to their flexibility,…

Hardware Architecture · Computer Science 2025-04-25 Pedro Antunes , Artur Podobas

Data-intensive scientific workflows increasingly rely on high-performance computing (HPC) systems, complementing traditional Grid and Cloud platforms. However, workflow scheduling on HPC infrastructures remains challenging due to the…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-11-26 Aurelio Vivas , Harold Castro

This paper presents a stream processor generator, called SPGen, for FPGA-based system-on-chip platforms. In our research project, we use an FPGA as a common platform for applications ranging from HPC to embedded/robotics computing.…

Other Computer Science · Computer Science 2014-08-25 Kentaro Sano , Hayato Suzuki , Ryo Ito , Tomohiro Ueno , Satoru Yamamoto

We present a novel approach to accelerate astrophysical hydrodynamical simulations. In astrophysical many-body simulations, GRAPE (GRAvity piPE) system has been widely used by many researchers. However, in the GRAPE systems, its function is…

Astrophysics · Physics 2009-11-11 N. Nakasato , T. Hamada , T. Fukushige

Multiphase compressible flows are often characterized by a broad range of space and time scales. Thus entailing large grids and small time steps, simulations of these flows on CPU-based clusters can thus take several wall-clock days.…

Convolutional Neural Networks (CNNs) are fundamental to deep learning, driving applications across various domains. However, their growing complexity has significantly increased computational demands, necessitating efficient hardware…

Machine Learning · Computer Science 2025-05-21 Junye Jiang , Yaan Zhou , Yuanhao Gong , Haoxuan Yuan , Shuanglong Liu

Hardware acceleration has emerged as a key research topic for supporting computationally intensive signal processing and artificial intelligence applications in 6G research and development studies. This paper presents an RF Network on Chip…

Signal Processing · Electrical Eng. & Systems 2026-05-11 A. Oguz Kislal , Osman Mert Yilmaz , Bengu Bilgic Keskin , Ibrahim Hokelek , Ali Gorcin

Heterogeneous systems consisting of general-purpose processors and different types of hardware accelerators are becoming more and more common in HPC systems. Especially FPGAs provide a promising opportunity to improve both performance and…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-08-28 Oliver Knodel , Rainer G. Spallek

The objective of our research is to demonstrate the practical usage and orders of magnitude speedup of real-world applications by using alternative technologies to support high performance computing. Currently, the main barrier to the…

Astrophysics · Physics 2007-11-22 Robert J. Brunner , Volodymyr V. Kindratenko , Adam D. Myers

Deep learning (DL) is becoming the cornerstone of numerous applications both in datacenters and at the edge. Specialized hardware is often necessary to meet the performance requirements of state-of-the-art DL models, but the rapid pace of…

Hardware Architecture · Computer Science 2025-12-16 Andrew Boutros , Aman Arora , Vaughn Betz

Intensive computation is entering data centers with multiple workloads of deep learning. To balance the compute efficiency, performance, and total cost of ownership (TCO), the use of a field-programmable gate array (FPGA) with…

Computer Vision and Pattern Recognition · Computer Science 2019-09-19 Xiaoyu Yu , Yuwei Wang , Jie Miao , Ephrem Wu , Heng Zhang , Yu Meng , Bo Zhang , Biao Min , Dewei Chen , Jianlin Gao

The modern trend in High-Performance Computing (HPC) involves the use of accelerators such as Graphics Processing Units (GPUs) alongside Central Processing Units (CPUs) to speed up numerical operations in various applications. Leading…

Mathematical Software · Computer Science 2025-07-25 Giulio Malenza , Giovanni Stabile , Filippo Spiga , Robert Birke , Marco Aldinucci

Among hardware accelerators for deep-learning inference, data flow implementations offer low latency and high throughput capabilities. In these architectures, each neuron is mapped to a dedicated hardware unit, making them well-suited for…

Machine Learning · Computer Science 2026-03-10 Tobias Habermann , Michael Mecik , Zhenyu Wang , César David Vera , Martin Kumm , Mario Garrido

FPGAs have found increasing adoption in data center applications since a new generation of high-level tools have become available which noticeably reduce development time for FPGA accelerators and still provide high quality of results.…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-06-15 Marius Meyer , Tobias Kenter , Christian Plessl

In this paper, the acceleration of algorithms using a design of a field programmable gate array (FPGA) as a prototype of a static dataflow architecture is discussed. The static dataflow architecture using operators interconnected by…

Hardware Architecture · Computer Science 2015-03-13 Jorge Luiz e Silva , Joelmir Jose Lopes , Bruno de Abreu Silva , Antonio Carlos Fernandes da Silva

Heterogeneous computing is one of the most important computational solutions to meet rapidly increasing demands on system performance. It typically allows the main flow of applications to be executed on a CPU while the most computationally…

Software Engineering · Computer Science 2020-12-11 Hugo Andrade , Ola Benderius , Christian Berger , Ivica Crnkovic , Jan Bosch

Field Programmable Gate Arrays (FPGAs) have the potential to accelerate specific HPC codes. However even with the advent of High Level Synthesis (HLS), which enables FPGA programmers to write code in C or C++, programming such devices still…

Programming Languages · Computer Science 2021-04-13 Nick Brown

Scientific simulation leveraging high-performance computing (HPC) systems is crucial for modeling complex systems and phenomena in fields such as astrophysics, climate science, and fluid dynamics, generating massive datasets that often…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-07-03 Wenqi Jia , Ying Huang , Jian Xu , Zhewen Hu , Sian Jin , Jiannan Tian , Yuede Ji , Miao Yin