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Cytoskeletons are self-organized networks based on polymerized proteins: actin, tubulin, and driven by motor proteins, such as myosin, kinesin and dynein. Their positive Darwinian evolution enables them to approach optimized functionality…

Other Quantitative Biology · Quantitative Biology 2020-11-04 J. C. Phillips

Taking inspiration from biological evolution, we explore the idea of "Can deep neural networks evolve naturally over successive generations into highly efficient deep neural networks?" by introducing the notion of synthesizing new highly…

Computer Vision and Pattern Recognition · Computer Science 2017-02-08 Mohammad Javad Shafiee , Akshaya Mishra , Alexander Wong

Cytoskeletons are self-organized networks based on polymerized proteins: actin, tubulin, and driven by motor proteins, such as myosin, kinesin and dynein. Their positive Darwinian evolution enables them to approach optimized functionality…

Other Quantitative Biology · Quantitative Biology 2020-08-21 J. C. Phillips

The complex and unique neural network topology of the human brain formed through natural evolution enables it to perform multiple cognitive functions simultaneously. Automated evolutionary mechanisms of biological network structure inspire…

Neural and Evolutionary Computing · Computer Science 2023-09-12 Wenxuan Pan , Feifei Zhao , Zhuoya Zhao , Yi Zeng

We review the development of thermodynamic protein hydropathic scaling theory, starting from backgrounds in mathematics and statistical mechanics, and leading to biomedical applications. Darwinian evolution has organized each protein family…

Molecular Networks · Quantitative Biology 2021-05-27 J. C. Phillips

We report on both analytical and numerical results concerning stochastic Hopfield--like neural automata exhibiting the following (biologically inspired) features: (1) Neurons and synapses evolve in time as in contact with respective baths…

Statistical Mechanics · Physics 2007-05-23 J. J. Torres , J. Marro , P. L. Garrido , J. M. Cortes , F. Ramos , M. A. Munoz

Neural codes appear efficient. Naturally, neuroscientists contend that an efficient process is responsible for generating efficient codes. They argue that natural selection is the efficient process that generates those codes. Although…

Neurons and Cognition · Quantitative Biology 2022-03-21 Han Kim

Recent efforts have shown machine learning to be useful for the prediction of nonlinear fluid dynamics. Predictive accuracy is often a central motivation for employing neural networks, but the pattern recognition central to the network…

Fluid Dynamics · Physics 2022-08-23 Shizheng Wen , Michael W. Lee , Kai M. Kruger Bastos , Earl H. Dowell

Conventional kinesin is a dimeric motor protein that transports membranous organelles toward the plus-end of microtubules (MTs). Individual kinesin dimers show steadfast directionality and hundreds of consecutive steps, yetthe detailed…

Biological Physics · Physics 2015-05-13 Zhisong Wang , Min Feng , Wenwei Zheng , Dagong Fan

Despite significant fluctuation under thermal noise, biological machines in cells perform their tasks with exquisite precision. Using molecular simulation of a coarse-grained model and theoretical arguments we envisaged how kinesin, a…

Biological Physics · Physics 2015-06-03 Changbong Hyeon , José N. Onuchic

We demonstrate, both analytically and numerically, that learning dynamics of neural networks is generically attracted towards a self-organized critical state. The effect can be modeled with quartic interactions between non-trainable…

Statistical Mechanics · Physics 2021-07-09 Mikhail I. Katsnelson , Vitaly Vanchurin , Tom Westerhout

Neural networks show a progressive increase in complexity during the time course of evolution. From diffuse nerve nets in Cnidaria to modular, hierarchical systems in macaque and humans, there is a gradual shift from simple processes…

Neurons and Cognition · Quantitative Biology 2011-12-23 Marcus Kaiser , Sreedevi Varier

The impressive lifelong learning in animal brains is primarily enabled by plastic changes in synaptic connectivity. Importantly, these changes are not passive, but are actively controlled by neuromodulation, which is itself under the…

Neural and Evolutionary Computing · Computer Science 2021-07-06 Thomas Miconi , Aditya Rawal , Jeff Clune , Kenneth O. Stanley

There has been significant recent interest towards achieving highly efficient deep neural network architectures. A promising paradigm for achieving this is the concept of evolutionary deep intelligence, which attempts to mimic biological…

Machine Learning · Computer Science 2016-11-23 Mohammad Javad Shafiee , Alexander Wong

A substantial amount of time and energy has been invested to develop machine vision using connectionist (neural network) principles. Most of that work has been inspired by theories advanced by neuroscientists and behaviorists for how…

Neurons and Cognition · Quantitative Biology 2020-09-01 Ernest Greene

Hydrodynamic theories effectively describe many-body systems out of equilibrium in terms of a few macroscopic parameters. However, such hydrodynamic parameters are difficult to derive from microscopics. Seldom is this challenge more…

Deep learning architectures are fundamentally inspired by neuroscience, particularly the structure of the brain's sensory pathways, and have achieved remarkable success in learning informative data representations. Although these…

Machine Learning · Computer Science 2026-03-26 Tongfei Chen , Jingying Yang , Linlin Yang , Jinhu Lü , David Doermann , Chunyu Xie , Long He , Tian Wang , Juan Zhang , Guodong Guo , Baochang Zhang

The evolution of cognition is frequently discussed as the evolution of cognitive abilities or the evolution of some neuronal structures in the brain. However, since such traits or abilities are often highly complex, understanding their…

Neurons and Cognition · Quantitative Biology 2025-06-27 Arnon Lotem , Joseph Y. Halpern

Biological nervous systems consist of networks of diverse, sophisticated information processors in the form of neurons of different classes. In most artificial neural networks (ANNs), neural computation is abstracted to an activation…

Neural and Evolutionary Computing · Computer Science 2023-06-12 Joachim Winther Pedersen , Sebastian Risi

We propose a working hypothesis supported by numerical simulations that brain networks evolve based on the principle of the maximization of their internal information flow capacity. We find that synchronous behavior and capacity of…

Neurons and Cognition · Quantitative Biology 2015-08-17 Chris G. Antonopoulos , Shambhavi Srivastava , Sandro E. de S. Pinto , Murilo S. Baptista
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