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The increasing volume of ecologically and biologically relevant data has revealed a wide collection of emergent patterns in living systems. Analyzing different datasets, ranging from metabolic gene-regulatory to species interaction…

Physics and Society · Physics 2019-12-13 Daniel M. Busiello , Samir Suweis , Jorge Hidalgo , Amos Maritan

There are many scales at which to quantify stability in spatial and ecological networks. Local-scale analyses focus on specific nodes of the spatial network, while regional-scale analyses consider the whole network. Similarly, species- and…

Populations and Evolution · Quantitative Biology 2022-10-19 Javier Jarillo , Francisco J. Cao-García , Frederik De Laender

The importance of studying properties of networks is manifest in diverse fields ranging from biology, engineering, physics, chemistry, neuroscience, and medicine. The functionality of networks with regard to performance, throughput,…

Molecular Networks · Quantitative Biology 2015-03-27 Allen Tannenbaum , Chris Sander , Liangjia Zhu , Romeil Sandhu , Ivan Kolesov , Eduard Reznik , Yasin Senbabaoglu , Tryphon Georgiou

Despite the impressive performance of Artificial Intelligence (AI) systems, their robustness remains elusive and constitutes a key issue that impedes large-scale adoption. Robustness has been studied in many domains of AI, yet with…

Artificial Intelligence · Computer Science 2022-10-20 Andrea Tocchetti , Lorenzo Corti , Agathe Balayn , Mireia Yurrita , Philip Lippmann , Marco Brambilla , Jie Yang

The interaction between natural selection and random mutation is frequently debated in recent years. Does similar dilemma also exist in the evolution of real networks such as biological networks? In this paper, we try to discuss this issue…

Statistical Mechanics · Physics 2009-01-07 Zhen Shao , Hai-jun Zhou

A convolutional neural network strongly robust to adversarial perturbations at reasonable computational and performance cost has not yet been demonstrated. The primate visual ventral stream seems to be robust to small perturbations in…

Machine Learning · Computer Science 2020-07-01 Manish V. Reddy , Andrzej Banburski , Nishka Pant , Tomaso Poggio

We construct and investigate Boolean networks that follow a given reliable trajectory in state space, which is insensitive to fluctuations in the updating schedule, and which is also robust against noise. Robustness is quantified as the…

Biological Physics · Physics 2010-12-02 Christoph Schmal , Tiago P. Peixoto , Barbara Drossel

Determining mechanistic models of gene regulation, especially underlying phenotypic variation, is a central goal of both mathematical biology and modern evolutionary biology. However, several challenges, involving both common…

Molecular Networks · Quantitative Biology 2025-11-04 Cody E. FitzGerald , Shelley Reich , Victor Agaba , Arjun Mathur , Michael S. Werner , Niall M. Mangan

Robust and efficient design of networks on a realistic geographical space is one of the important issues for the realization of dependable communication systems. In this paper, based on a percolation theory and a geometric graph property,…

Data Analysis, Statistics and Probability · Physics 2011-11-04 Yukio Hayashi

[Background] Several studies have mentioned network modularity -- that a network can easily be decomposed into subgraphs that are densely connected within and weakly connected between each other -- as a factor affecting metabolic…

Molecular Networks · Quantitative Biology 2012-10-10 Petter Holme

The past decade has witnessed the development and success of coarse-grained network models of proteins for predicting many equilibrium properties related to collective modes of motion. Curiously, the results are usually robust towards the…

Molecular Networks · Quantitative Biology 2008-09-23 Canan Atilgan , Ibrahim Inanc , Ali Rana Atilgan

A central biological question is how natural organisms are so evolvable (capable of quickly adapting to new environments). A key driver of evolvability is the widespread modularity of biological networks--their organization as functional,…

Populations and Evolution · Quantitative Biology 2015-03-13 Jeff Clune , Jean-Baptiste Mouret , Hod Lipson

Evolution depends on the possibility of successfully exploring fitness landscapes via mutation and recombination. With these search procedures, exploration is difficult in "rugged" fitness landscapes, where small mutations can drastically…

Adaptation and Self-Organizing Systems · Physics 2016-09-08 Carlos Gershenson , Stuart A. Kauffman , Ilya Shmulevich

Complex networks have been shown to be robust against random structural perturbations, but vulnerable against targeted attacks. Robustness analysis usually simulates the removal of individual or sets of nodes, followed by the assessment of…

Molecular Networks · Quantitative Biology 2012-11-13 Oriol Güell , Francesc Sagués , Georg Basler , Zoran Nikoloski , M. Ángeles Serrano

Determining design principles that boost robustness of interdependent networks is a fundamental question of engineering, economics, and biology. It is known that maximizing the degree correlation between replicas of the same node leads to…

Physics and Society · Physics 2019-08-21 Ivan Kryven , Ginestra Bianconi

A classic measure of ecological stability describes the tendency of a community to return to equilibrium after small perturbation. While many advances show how the network structure of these communities severely constrains such tendencies,…

Populations and Evolution · Quantitative Biology 2015-06-09 Gang Yan , Neo D. Martinez , Yang-Yu Liu

When a biological system robustly corrects component-level errors, the direct pressure on component performance declines. Components may become less reliable, maintain more genetic variability, or drift neutrally in design, creating the…

Populations and Evolution · Quantitative Biology 2023-12-27 Steven A. Frank

The network approach became a widely used tool to understand the behaviour of complex systems in the last decade. We start from a short description of structural rigidity theory. A detailed account on the combinatorial rigidity analysis of…

Biological Physics · Physics 2012-12-04 Merse E. Gaspar , Peter Csermely

We study notions of robustness of Markov kernels and probability distribution of a system that is described by $n$ input random variables and one output random variable. Markov kernels can be expanded in a series of potentials that allow to…

Commutative Algebra · Mathematics 2011-10-07 Johannes Rauh , Nihat Ay

In spite of a few attempts in understanding the dynamical robustness of complex networks, this extremely important subject of research is still in its dawn as compared to the other dynamical processes on networks. We hereby consider the…

Adaptation and Self-Organizing Systems · Physics 2022-03-24 Soumen Majhi