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Gene expression can be used to subtype breast cancer with improved prediction of risk of recurrence and treatment responsiveness over that obtained using routine immunohistochemistry (IHC). However, in the clinic, molecular profiling is…

Computer Vision and Pattern Recognition · Computer Science 2023-05-09 Raktim Kumar Mondol , Ewan K. A. Millar , Peter H Graham , Lois Browne , Arcot Sowmya , Erik Meijering

Pinching-antenna (PA) has recently attracted considerable research attention in wireless systems, realized by attaching small dielectric particles along a waveguide. Building upon which, the segmented waveguide-enabled pinching-antenna…

Signal Processing · Electrical Eng. & Systems 2026-04-02 Yue Geng , Tee Hiang Cheng , Kah Chan Teh , Zhiguo Ding

In this paper, we explore a novel image matting task aimed at achieving efficient inference under various computational cost constraints, specifically FLOP limitations, using a single matting network. Existing matting methods which have not…

Computer Vision and Pattern Recognition · Computer Science 2025-03-06 Qinglin Liu , Zonglin Li , Xiaoqian Lv , Xin Sun , Ru Li , Shengping Zhang

Principles of feedback control have been shown to naturally arise in biological systems and successfully applied to build synthetic circuits. In this work we consider Biochemical Reaction Networks (CRNs) as a paradigm for modelling…

Systems and Control · Computer Science 2019-03-26 Max Whitby , Luca Cardelli , Marta Kwiatkowska , Luca Laurenti , Mirco Tribastone , Max Tschaikowski

CRISPR-based diagnostics have gained increasing attention as biosensing tools able to address limitations in contemporary molecular diagnostic tests. To maximise the performance of CRISPR-based assays, much effort has focused on optimizing…

Quantitative Methods · Quantitative Biology 2025-01-09 Nathan Khosla , Jake M. Lesinski , Marcus Haywood-Alexander , Andrew J. deMello , Daniel A. Richards

The minimum action method (MAM) is to calculate the most probable transition path in randomly perturbed stochastic dynamics, based on the idea of action minimization in the path space. The accuracy of the numerical path between different…

Computational Physics · Physics 2017-05-26 Y Sun , X Zhou

Compute in-memory (CIM) is a promising technique that minimizes data transport, the primary performance bottleneck and energy cost of most data intensive applications. This has found wide-spread adoption in accelerating neural networks for…

Hardware Architecture · Computer Science 2020-08-18 Brian Crafton , Samuel Spetalnick , Gauthaman Murali , Tushar Krishna , Sung-Kyu Lim , Arijit Raychowdhury

Face recognition technology has been widely used in daily interactive applications such as checking-in and mobile payment due to its convenience and high accuracy. However, its vulnerability to presentation attacks (PAs) limits its reliable…

Computer Vision and Pattern Recognition · Computer Science 2022-12-08 Zitong Yu , Chenxu Zhao , Zhen Lei

Cryo-electron microscopy (cryo-EM) remains pivotal in structural biology, yet the task of protein particle picking, integral for 3D protein structure construction, is laden with manual inefficiencies. While recent AI tools such as Topaz and…

Computer Vision and Pattern Recognition · Computer Science 2023-11-29 Fei He , Zhiyuan Yang , Mingyue Gao , Biplab Poudel , Newgin Sam Ebin Sam Dhas , Rajan Gyawali , Ashwin Dhakal , Jianlin Cheng , Dong Xu

Face anti-spoofing (FAS) plays a vital role in securing face recognition systems. Existing methods heavily rely on the expert-designed networks, which may lead to a sub-optimal solution for FAS task. Here we propose the first FAS method…

Computer Vision and Pattern Recognition · Computer Science 2020-11-05 Zitong Yu , Jun Wan , Yunxiao Qin , Xiaobai Li , Stan Z. Li , Guoying Zhao

The advancement of novel combinatorial CRISPR screening technologies enables the identification of synergistic gene combinations on a large scale. This is crucial for developing novel and effective combination therapies, but the…

Genomics · Quantitative Biology 2024-12-12 Jason Qin , Hans-Hermann Wessels , Carlos Fernandez-Granda , Yuhan Hao

Language Models (LMs) are increasingly used in applications where generated outputs must satisfy strict semantic or syntactic constraints. Existing approaches to constrained generation fall along a spectrum: greedy constrained decoding…

Artificial Intelligence · Computer Science 2025-10-03 Paweł Parys , Sairam Vaidya , Taylor Berg-Kirkpatrick , Loris D'Antoni

Activity and property prediction models are the central workhorses in drug discovery and materials sciences, but currently they have to be trained or fine-tuned for new tasks. Without training or fine-tuning, scientific language models…

Biomolecules · Quantitative Biology 2023-06-19 Philipp Seidl , Andreu Vall , Sepp Hochreiter , Günter Klambauer

We investigate the protein expression pattern of the lamB gene in Escherichia coli LE392. The gene product LamB is an important membrane protein for maltose transport into cells but it is also exploited by bacteriophage lambda for…

Cell Behavior · Quantitative Biology 2008-08-08 Emily Chapman-McQuiston , Chuck Yeung , X. L. Wu

This paper proposes Bayes-optimal convolutional approximate message-passing (CAMP) for signal recovery in compressed sensing. CAMP uses the same low-complexity matched filter (MF) for interference suppression as approximate message-passing…

Information Theory · Computer Science 2021-04-05 Keigo Takeuchi

Segmenting medical images accurately and reliably is important for disease diagnosis and treatment. It is a challenging task because of the wide variety of objects' sizes, shapes, and scanning modalities. Recently, many convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2023-02-22 Ange Lou , Shuyue Guan , Murray Loew

The model for cAMP-dependent synaptic plasticity relates the characterization of a noradrenaline-stimulated adenylyl cyclase with DNA unzipping. Specific proteins condition cAMP insertion in specific sites of the DNA structure to direct…

Biomolecules · Quantitative Biology 2016-06-28 Alfred Bennun

Deep neural networks (DNNs) often have to be compressed, via pruning and/or quantization, before they can be deployed in practical settings. In this work we propose a new compression-aware minimizer dubbed CrAM that modifies the…

Machine Learning · Computer Science 2023-05-05 Alexandra Peste , Adrian Vladu , Eldar Kurtic , Christoph H. Lampert , Dan Alistarh

A key aim of systems biology is the reconstruction of molecular networks, however we do not yet have networks that integrate information from all datasets available for a particular clinical condition. This is in part due to the limited…

Recently, the pinching antenna system (PASS) has attracted considerable attention due to their advantages in flexible deployment and reduction of signal propagation loss. In this work, a multiple waveguide PASS assisted integrated sensing…

Signal Processing · Electrical Eng. & Systems 2026-01-01 Haochen Li , Ruikang Zhong , Jiayi Lei , Yuanwei Liu